A5025795757- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Crystal structures of chemical compounds
- Magnetism in coordination complexes
- Crystallography and molecular interactions
- Protein Interaction Studies and Fluorescence Analysis
- Metal-Organic Frameworks: Synthesis and Applications
- Reproductive System and Pregnancy
- Metal-Catalyzed Oxygenation Mechanisms
- Endometriosis Research and Treatment
- Lanthanide and Transition Metal Complexes
- Organometallic Compounds Synthesis and Characterization
- Pharmacological Effects of Natural Compounds
- Various Chemistry Research Topics
- Pregnancy and Medication Impact
- Synthesis and biological activity
- Chemical Thermodynamics and Molecular Structure
- Ferrocene Chemistry and Applications
- Organic and Molecular Conductors Research
- Cancer therapeutics and mechanisms
- Inflammatory mediators and NSAID effects
- Synthesis and Characterization of Heterocyclic Compounds
- Porphyrin and Phthalocyanine Chemistry
- Nonlinear Optical Materials Research
University of Pavol Jozef Šafárik
2016-2025
Technical University of Košice
2015-2016
Three mononuclear complexes [Co<sup>II</sup>(biq)X<sub>2</sub>] (biq = 2,2′-biquinoline; X Cl, Br, I) possess a sizable magnetic anisotropy, and they display superparamagnetic behaviour in an applied external field that culminates between<italic>B</italic><sub>DC</sub>= 0.2–0.3 T.
Inadequate angiogenesis of endometriotic implants stimulated by the inflammatory microenvironment in uterine region leads to development gynecological diseases, which significantly reduce fertility and vitality young women. Angiogenic processes are controlled factors whose activities regulated at gene level reactive oxygen species (ROS), hypoxia-induced (HIFs), zinc-finger proteins (ZnFs) or posttranscriptionally via non-coding RNAs. The cooperation these is responsible for manifestation...
Chlorido complex [Co(bcp)Cl<sub>2</sub>] exhibits a field-induced SMM behaviour, while in the bromide and iodido analogues only weak antiferromagnetic interactions are present.
The mononuclear tetracoordinate [Co(dmphen)X 2 ] (dmphen = 2,9‐dimethyl‐1,10‐phenanthroline neocuproine; X Cl, Br, I) complexes were prepared by a solvothermal method. X‐ray diffraction experiments showed that they possess analogous molecular structures, even though the chlorido complex crystallizes in different crystal system and space group. structures of are stabilized π–π interactions. Alternating‐current (AC) susceptibility measurements show bromido iodido behave as field‐induced...
Abstract Three variants of novel cobalt(II) complex with deprotonated mefenamic acid ( mef ) and N,N ′-donor ligand neocuproine neo are described, namely; two differently colored shaped crystal polymorphs [Co( 2 )] 1a 1b a pyridine solvate )]· py ). The complexes have been characterized by infrared UV-VIS spectroscopy, elemental analysis single-crystal X-ray structure analysis. Although the , crystallize in different systems space groups differ shapes coordination polyhedra, structures all...
Abstract Endometriosis is a chronic inflammatory disease which increasingly affects young women under 35 years of age and leads to subfertility even infertility. Analysis the cytotoxic effect zinc(II) niflumato complex with neocuproine ([Zn( neo )( nif ) 2 ] or Zn-Nif) on immortalized human endometriotic cell line (12Z) control endometrial stromal (hTERT) was performed using xCELLigence technology for approximately 72 h following treatment Zn-Nif as well viability Trypan Blue Assay. 12Z...
Two isostructural complexes [Mn(neo)(fen) 2 ] (1) and [Mn(neo)(flu) (2) show different biological activity on endometrial cell lines. Flufenamato complex effectively triggers apoptosis mediated by caspase activation in endometriotic 12Z line.
Mixed-ligand complexes featuring a carboxylato ligand and bidentate chelate N,N′-donor ligands along with single halogenido are rarely subjected to studies despite their interesting physical, chemical biological properties. A direct synthesis involving non-steroidal anti-inflammatory drugs flufenamic acid niflumic sterically hindering (neocuproine 2,2′-biquinoline) has been used prepare mononuclear mixed-ligand zinc composition of [ZnCl(flu)(neo)] (1A 1B) [ZnCl(nif)(biq)] (2). Single-crystal...
Three novel complexes of deprotonated diflunisal (dif) with neocuproine (neo) were synthesized and characterized by elemental, spectral (UV-Vis, FTIR, fluorescence, mass spectrometry) single-crystal X-ray diffraction analysis. Although, the compounds...
A new zirconium(IV) complex, diaquabis(8-hydroxyquinoline-2-carboxylato-κ 3 N , O 2 8 )zirconium(IV) dimethylformamide disolvate, [Zr(C 10 H 5 NO ) (H O) ]·2C 7 or [Zr(QCa) ]·2DMF ( 1 (HQCaH is 8-hydroxyquinoline-2-carboxylic acid and DMF dimethylformamide), was prepared characterized by elemental analysis, IR spectroscopy single-crystal X-ray structure analysis. Complex a mononuclear complex in which the Zr IV atoms sit on twofold axis they are octacoordinated two six of tridentate anionic...
Endometriosis and endometrial cancer are closely related to oxidative stress. However, the direct relationship between copper zinc levels stress in extracellular intracellular space remains unclear. The presented study is focused on determination of serum Zn Cu levels, glutathione concentration enzyme activity three groups: patients diagnosed with (EC), endometriosis (EM), a healthy control group. Spectrophotometric trace elements revealed that were lower blood plasma as compared other...