A5028808876- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Trauma and Emergency Care Studies
- Disaster Response and Management
- Mechanical Circulatory Support Devices
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Simulation-Based Education in Healthcare
- Hospital Admissions and Outcomes
- Injury Epidemiology and Prevention
- Healthcare Policy and Management
- Trauma Management and Diagnosis
- Sepsis Diagnosis and Treatment
- Congenital Heart Disease Studies
- Intensive Care Unit Cognitive Disorders
- Tendon Structure and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Foot and Ankle Surgery
- Meningioma and schwannoma management
- Electrolyte and hormonal disorders
- Pain Management and Treatment
- Complement system in diseases
- Non-Invasive Vital Sign Monitoring
University of Pennsylvania
2021-2025
Children's Hospital of Philadelphia
2020-2025
Philadelphia University
2021-2024
Mater Misericordiae University Hospital
2022-2024
Cork University Hospital
2023
Children's Hospital of San Antonio
2021
Harvard University
2020
Boston Children's Hospital
2019-2020
Beth Israel Deaconess Medical Center
2020
Boston Children's Museum
2019
Microfracture is the most common cartilage-reparative procedure for treatment of osteochondral lesions talus (OLTs). Damage to subchondral bone (SCB) during microfracture may irreversibly change joint-loading support ankle, leading reparative fibrocartilage degradation over time.To investigate morphological in SCB after OLT by developing a novel magnetic resonance imaging (MRI) scoring system specifically evaluating SCB. Furthermore, this study assesses influence changes on clinical outcomes...
To characterize chest compression (CC) pause duration during the last 5 minutes of pediatric cardiopulmonary resuscitation (CPR) prior to extracorporeal-CPR (E-CPR) cannulation and association with survival outcomes.Cohort study from a quality collaborative including E-CPR cardiac arrest events ≥ 10 min CPR data. We characterized CC interruptions defibrillator-electrode recorded (prior cannulation) assessed between longest outcomes using multivariable logistic regression.Of 49 events, median...
This is a novel case of 16-month-old boy with history prematurity intrauterine growth restriction, severe failure to thrive, microcephaly, pachygyria, agenesis the corpus callosum, and postnatal embolic stroke, who presented new-onset diabetes mellitus diabetic ketoacidosis in setting acute respiratory syndrome coronavirus 2 infection, course complicated by atypical hemolytic (aHUS). patient demonstrated remarkable insulin resistance period before aHUS diagnosis, which resolved first dose...
Importance Cardiopulmonary resuscitation (CPR) duration is associated with cardiac arrest survival. Objectives To describe characteristics CPR among hospitalized children without return of circulation (ROC) (patient-level analysis) and determine whether hospital median in patients ROC survival (hospital-level analysis). Design, Setting, Participants This retrospective cohort study undergoing pediatric in-hospital between January 1, 2000, December 31, 2021, used data from the Get With...
IMPORTANCE: A recent study showed an association between high hospital-level noninvasive positive pressure ventilation (NIPPV) use and in-hospital cardiac arrest (IHCA) in children with bronchiolitis. OBJECTIVES: We aimed to determine if patient-level exposure NIPPV bronchiolitis was associated IHCA. DESIGN, SETTING AND PARTICIPANTS: Retrospective cohort at a single-center quaternary PICU North America including International Classification of Diseases primary or secondary diagnoses the...
Abstract Systems to detect and respond deteriorating hospitalized children are common despite little evidence supporting best practices. Our objective was describe systems detect/respond at Pediatric Resuscitation Quality Collaborative (pediRES‐Q) institutions. We performed a cross‐sectional survey of pediRES‐Q leaders. Questionnaire design utilized expert validation cognitive interviews. Thirty centers (88%) responded. Most (93%) used ≥1 system deterioration: most commonly, early warning...
To develop a consensus framework that can guide the process of classifying and reviewing pediatric in-hospital cardiac arrest in PICU.A three-round electronic Delphi study with an additional in-person session resuscitation experts. The modified consisted survey questions sent to expert panel goals (1) achieving on definitions avoidable, potentially unavoidable PICU (2) ranking list factors contribute avoidable arrest.Electronic surveys experts including critical care, emergency medicine,...
Abstract Objective We aimed to describe the risk factors and outcomes of recurrent in-hospital cardiac arrest (IHCA) in a large pediatric cohort. Methods A retrospective cohort study patients ≤18 years from American Heart Association's Get With The Guidelines®-Resuscitation Registry with single or IHCA who achieved return spontaneous circulation were not placed on extracorporeal membrane oxygenation their initial included. Patients categorized into two groups for analysis: (1) (2) ICHA....
Abstract Background Black patients have worse outcomes after in-hospital cardiac arrest (IHCA). Whether these racial disparities are associated with medical emergency team (MET) evaluation prior to IHCA remains unknown. Methods A retrospective cohort study of adults age ≥ 18 years from the American Heart Association Get With The Guidelines® Resuscitation registry who had an between 2000 and 2021 acute physiologic decline (modified early warning score [MEWS] 3) during 24 hours IHCA....
Half of pediatric in-hospital cardiopulmonary resuscitation (CPR) events have an initial rhythm non-pulseless bradycardia with poor perfusion. Our study objectives were to leverage granular data from the ICU-RESUScitation (ICU-RESUS) trial to: (1) determine association early epinephrine administration survival outcomes in children receiving CPR for perfusion; and (2) describe incidence time course development pulselessness.
Background: CPR quality is an important modifiable component of cardiac arrest care. Current chest compression (CC) guidelines were primarily generated from out-of-hospital data. However, they are applied to arrests in all contexts, including in-hospital. Aims: We aimed to: 1) quantitatively describe in-hospital (IHCA) CC metrics; 2) determine the association current AHA guideline-recommended metrics with IHCA outcomes; and 3) discover new targets using data quantify their outcomes....
Introduction: The physiologic response to epinephrine during pediatric CPR varies and poor is associated with worse outcomes. Though vasopressin not recommended by guidelines, laboratory data show a among non-responders. We aimed explore the IHCA. Hypothesis: Vasopressin an increase in diastolic blood pressure (DBP) compared patients ≥1 dose of epinephrine. Methods: Single-center retrospective cohort study ICU IHCAs prospectively collected arrest event (2017-2023). subjects received...
A 14-year-old boy with attention-deficit/hyperactivity disorder, depression, autism spectrum and astrocytoma (status-post resection in infancy, no residual deficits) presents to the emergency department (ED) 2 days of abnormal movements: facial twitching, jaw stiffness, torticollis, progressing whole-body tremors, agitation, diaphoresis, altered mental status. Medications include fluoxetine 60 mg daily lisdexamfetamine daily, started 1 year ago. He recently gained independence taking...
This study aimed to describe baseline and event characteristics outcomes for adult patients who experience in-hospital cardiac arrest (IHCA) in a quaternary children's hospital compare IHCA younger (18-24 years) versus older (≥25 adults. We hypothesized that the rate of survival discharge would be lower group.We performed retrospective single-center cohort inpatient areas center. Adult (≥18 years age) with an index pulseless requiring at least 1 minute cardiopulmonary resuscitation or...