A5077140049- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Chromosomal and Genetic Variations
- Identification and Quantification in Food
- Turtle Biology and Conservation
- Ichthyology and Marine Biology
- Amphibian and Reptile Biology
- Evolution and Paleontology Studies
- Genetic and phenotypic traits in livestock
- Molecular Biology Techniques and Applications
- Bat Biology and Ecology Studies
- Physiological and biochemical adaptations
- Parasites and Host Interactions
- Environmental DNA in Biodiversity Studies
- Wildlife Ecology and Conservation
- Paleontology and Evolutionary Biology
- Marine animal studies overview
- Animal Behavior and Reproduction
- Machine Learning in Bioinformatics
- Parasite Biology and Host Interactions
- interferon and immune responses
- Helminth infection and control
- Plant Disease Resistance and Genetics
- Plant Virus Research Studies
- Immune Cell Function and Interaction
College of Charleston
2011-2023
NCCOS Hollings Marine Laboratory
2014-2023
Medical University of South Carolina
2013-2023
Harvard University
2004-2010
University of Washington
1992-2007
Google (United States)
2005
Sokoine University of Agriculture
2004
Fred Hutch Cancer Center
2004
RELX Group (Netherlands)
2004
The Institute of Statistical Mathematics
2000-2001
The evolution of the amniotic egg was one great evolutionary innovations in history life, freeing vertebrates from an obligatory connection to water and thus permitting conquest terrestrial environments. Among amniotes, genome sequences are available for mammals birds, but not non-avian reptiles. Here we report sequence North American green anole lizard, Anolis carolinensis. We find that A. carolinensis microchromosomes highly syntenic with chicken microchromosomes, yet do exhibit high GC...
We describe the genome of western painted turtle, Chrysemys picta bellii, one most widespread, abundant, and well-studied turtles. place into a comparative evolutionary context, focus on genomic features associated with tooth loss, immune function, longevity, sex differentiation determination, species' physiological capacities to withstand extreme anoxia tissue freezing.Our phylogenetic analyses confirm that turtles are sister group living archosaurs, demonstrate an extraordinarily slow rate...
Abstract Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni . With World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize genome glabrata, lophotrochozoan protostome, and provide timely important information biology. We describe aspects phero-perception, stress responses, immune function regulation gene expression that support...
SINE (short interspersed element) insertion analysis elucidates contentious aspects in the phylogeny of toothed whales and dolphins (Odontoceti), especially river dolphins. Here, we characterize 25 informative SINEs inserted into unique genomic loci during evolution odontocetes to construct a cladogram, determine total 2.8 kb per taxon flanking sequences these estimate divergence times among lineages. We demonstrate that: ( i ) Odontocetes are monophyletic; ii Ganges River dolphins, beaked...
Resurgence of illicit trade in African elephant ivory is placing the at renewed risk. Regulation this could be vastly improved by ability to verify geographic origin tusks. We address need developing a combined genetic and statistical method determine poached ivory. Our approach exploits smoothing estimate geographic-specific allele frequencies over entire elephants' range for 16 microsatellite loci, using 315 tissue 84 scat samples from forest ( Loxodonta africana cyclotis ) savannah...
We report results of a megabase-scale phylogenomic analysis the Reptilia, sister group mammals. Large-scale end-sequence scanning genomic clones turtle, alligator, and lizard reveals diverse, mammal-like landscapes retroelements simple sequence repeats (SSRs) not found in chicken. Several global traits, including distinctive phylogenetic lineages CR1-like long interspersed elements (LINEs) paucity A-T rich SSRs, characterize turtles archosaur genomes, whereas higher frequencies tandem lower...
The teleost order Lophiiformes, commonly known as the anglerfishes, contains a diverse array of marine fishes, ranging from benthic shallow-water dwellers to highly modified deep-sea midwater species. They comprise 321 living species placed in 68 genera, 18 families and 5 suborders, but approximately half diversity is occupied by ceratioids distributed among 11 families. evolutionary origins such remarkable habitat diversity, however, remain elusive because lack fresh material for majority...
Goats (Capra hircus) are one of the oldest domesticated species, and they kept all over world as an essential resource for meat, milk, fiber. Although recent archeological molecular biological studies suggested that originated in West Asia, their domestication processes such timing population expansion dynamics selection pressures little known. With aim addressing these issues, nearly complete mitochondrial protein-encoding genes were determined from East, Southeast, South Asian populations....
Advances in genome sciences are demonstrating the dynamic nature of noncoding DNA regions, which comprised largely repetitive elements with no apparent function. Retroposons one class mobile genetic that amplify and move about via a copy-and-paste mechanism employs an RNA intermediate. Short long interspersed (SINEs LINEs, respectively) types retroposons particular interest because their active role shaping architecture genomes diagnostic value as evolutionary markers for studies phylogeny...
The two living groups of flying vertebrates, birds and bats, both have constricted genome sizes compared with their close relatives. But nothing is known about the genomic characteristics pterosaurs, which took to air over 70 Myr before were first group vertebrates evolve powered flight. Here, we estimate size for four species pterosaurs seven basal archosauromorphs using a Bayesian comparative approach. Our results suggest that small genomes commonly associated flight in bats also evolved...
ANDREW M. SHEDLOCK,1,2 MICHELC. MILINKOVITCH,3 AND NORIHIRO OKADA1,4 Tokyo Institute of Technology, Molecular Evolution Laboratory, Graduate School Bioscience and Biotechnology, Yokohama, Japan The Statistical Mathematics, Systematics Group, Tokyo, Free University Brussels, cp300, Unit Evolutionary Genetics, Biology Medicine, 6041 Gosselies, Belgium
It is unlikely that taxonomically diverse phylogenetic studies will be completed rapidly in the near future for nonmodel organisms on a whole-genome basis. However, one approach to advancing field of "phylogenomics" estimate structure poorly known genomes by mining libraries clones from suites taxa, rather than single species. The present analysis adopts this taking advantage megabase-scale end-sequence scanning reptilian genomic characterize diversity CR1-like LINEs, dominant family...
Abstract Damselflies and dragonflies (Order: Odonata) play important roles in both aquatic terrestrial food webs can serve as sentinels of ecosystem health predictors population trends other taxa. The habitat requirements limited dispersal lotic damselflies make them especially sensitive to loss fragmentation. As such, landscape genomic studies these taxa help focus conservation efforts on watersheds with high levels genetic diversity, local adaptation, even cryptic endemism. Here, part the...
Short interspersed nuclear elements (SINEs) have been used to generate unambiguous phylogenetic topologies relating eukaryotic taxa. The irreversible nature of SINE retroposition is supported by a large body comparative genome data and fundamental assumption inherent in the value this qualitative method inference. Here, we assess key unidirectional insertion comparing insertion–derived topology tree based on seven independent loci five taxa order Cetartiodactyla (Cetacea + Artiodactyla)....