Lihua Chu

ORCID: 0000-0001-9579-121X
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Anesthesia and Pain Management
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Acute Ischemic Stroke Management
  • Spine and Intervertebral Disc Pathology
  • Sepsis Diagnosis and Treatment
  • Nosocomial Infections in ICU
  • Catalytic Cross-Coupling Reactions
  • Helicobacter pylori-related gastroenterology studies
  • Gastric Cancer Management and Outcomes
  • Antibiotic Use and Resistance
  • Climate Change and Health Impacts
  • Anesthesia and Neurotoxicity Research
  • Pneumonia and Respiratory Infections
  • Enhanced Recovery After Surgery
  • Clinical Reasoning and Diagnostic Skills
  • Thermal Regulation in Medicine
  • Trauma and Emergency Care Studies
  • Trauma Management and Diagnosis
  • Antibiotic Resistance in Bacteria
  • Hemodynamic Monitoring and Therapy
  • Gastroesophageal reflux and treatments
  • Nausea and vomiting management
  • Cardiovascular Health and Disease Prevention

Zhejiang University
2017-2022

First Affiliated Hospital Zhejiang University
2017-2020

Children's Hospital of Zhejiang University
2018

Merck & Co., Inc., Rahway, NJ, USA (United States)
1997-2016

The definition of sepsis was updated to sepsis-3 in February 2016. However, the performance previous and new remains unclear China. This a retrospective multicenter study six intensive care unit (ICUs) from five university-affiliated hospitals compare between sepsis-1 From May 1, 2016 June 2016, 496 patients were enrolled consecutively. Data extracted electronic clinical records. We evaluated by measuring area under receiver operating characteristic curves (AUROC) predict 28-day mortality...

10.1097/shk.0000000000000868 article EN Shock 2017-04-27

Abstract Background: The World Health Organization (WHO) has endorsed school bystander cardiopulmonary resuscitation (CPR) training programs. But related researches in China are limited. Therefore, we conducted this study to assess CPR children and the impact of neighborhood socio-economic status (SES) on. Methods: A total 1,093 students from seven schools Zhejiang province participated study. Theoretical practical were instructor-led classes. Students completed a 10-statement questionnaire...

10.1097/md.0000000000012673 article EN cc-by-nc Medicine 2018-10-01

Background: The aim of this study was to analyze the global trends sepsis research and investigate China's contribution by comparing quantity quality sepsis-related publications. Methods: Sepsis-related publications were main retrieved from Web Science online database using keywords "sepsis" or "septic shock." Bibliometric indicators, including number publications, total citation frequency, frequency per paper, h-index, type, orientation, organization, author, journal, funding support...

10.1097/md.0000000000007275 article EN cc-by-nc Medicine 2017-06-01

Despite being less invasive, patients who underwent video-assisted thoracic surgery (VATS) suffered considerable postoperative pain. Paravertebral block (PVB) was proven to provide effective analgesia in with VATS; however, there is no difference pain relief between preoperative PVB and PVB. This study aimed investigate the analgesic efficacy of combination on same patient undergoing VATS. In this prospective, double-blinded, randomized controlled trial, 44 VATS were enrolled, they received...

10.1155/2019/9158653 article EN cc-by Pain Research and Management 2019-11-18

Cerebral microembolic signal (MES) is an independent predictor of stroke risk and prognosis. The objective this study to assess the effects apixaban, as a representative novel oral anticoagulant class, on rabbit model cerebral MES. A clinical transcranial Doppler ultrasound instrument was used MESs in middle artery 30% FeCl<sub>3</sub>-induced carotid arterial thrombosis male New Zealand White rabbits. Ascending doses apixaban were evaluated monotherapy combination with aspirin both...

10.1124/jpet.116.234575 article EN Journal of Pharmacology and Experimental Therapeutics 2016-07-06

DEFA1/DEFA3, genes encoding human neutrophil peptides (HNP) 1-3, display wide-ranging copy number variations (CNVs) and is functionally associated with innate immunity infections. To identify potential associations between DEFA1/DEFA3 CNV hospital-acquired infections (HAIs), we enrolled 106 patients HAIs 109 controls in the intensive care unit (ICU) examined their CNVs. ranged from 2 to 16 per diploid genome all 215 critically ill patients, a median of 7 copies. In HAIs, varied 12 6, which...

10.1155/2018/2152650 article EN cc-by Mediators of Inflammation 2018-01-01

Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions.A retrospective, cohort, single center 226 patients who...

10.1186/s12871-021-01312-x article EN cc-by BMC Anesthesiology 2021-03-30

We aimed to develop a predictive difficult caudal epidural blockade (pDCEB) model when ultrasound was not available and verified the role of in (CEB).From October 2018 March 2019, this study consisted three phases. First, we prospectively enrolled 202 patients scheduled undergo anesthesia assessed risk factors by binary logistic regression scoring system. Second, 87 validate it. The receiver operating characteristic (ROC) curve used evaluate performance prediction model. Youden-index...

10.1155/2022/2037904 article EN Evidence-based Complementary and Alternative Medicine 2022-11-04

Objective To investigate the effect of ultrasound-guided stellate ganglion block (SGB) on perioperative inflammatory responses and postoperative recovery gastrointestinal function in patients undergoing surgery. Methods Fifty-five American Society Anesthesiologists physical class Ⅰ-Ⅲ both sexes, aged 18-64 yr, weighing 50-75 kg, elective surgery, were divided into SGB group (n=18) control (C group, n=37) using a random number table method.Ultrasound-guided was conducted with 0.5%...

10.3760/cma.j.issn.0254-1416.2018.08.003 article EN Zhonghua mazuixue zazhi 2018-08-20

Abstract Background: Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions. Methods: A retrospective, cohort, single...

10.21203/rs.3.rs-41225/v1 preprint EN cc-by Research Square (Research Square) 2020-07-14

Abstract Background: Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions. Methods: A retrospective, cohort, single...

10.21203/rs.3.rs-41225/v3 preprint EN cc-by Research Square (Research Square) 2020-12-31

Abstract Background : We aimed to develop a predictive difficult caudal epidural blockade (pDCEB) model when ultrasound was not available and verify the role of in blockade(CEB). Methods This study consisted three phases. First, we prospectively enrolled 202 patients assessed risk factors scoring system. Second, 87 validate it. Third, 68 with high CEB (pDCEB score ≥ 3) randomized them into landmark groups ultrasound. Result The rate 14.98% overall 289 patients. found correlation unclear...

10.21203/rs.3.rs-1016146/v1 preprint EN cc-by Research Square (Research Square) 2021-11-15

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199736226 article EN ChemInform 1997-09-02

Two of the most reproducible animal models used to study cerebrovascular related changes involve surgical occlusion cerebral vessels or introduction an embolic material into system. The present paper reports ultrastructural evaluation parenchymal and arterial response following embolization as compared with those induced by vascular clipping. Six adult baboons (papio anubis) were anesthetized after preparations for physiological monitoring completed embolus was injected through left carotid...

10.1017/s0424820100080559 article EN Proceedings annual meeting Electron Microscopy Society of America 1977-01-01
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