A5080092018- Thermal Regulation in Medicine
- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Sepsis Diagnosis and Treatment
- Sleep and Wakefulness Research
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Hemodynamic Monitoring and Therapy
- Spine and Intervertebral Disc Pathology
- Anesthesia and Sedative Agents
- Nosocomial Infections in ICU
- Airway Management and Intubation Techniques
- Neonatal Respiratory Health Research
- Pneumonia and Respiratory Infections
- Clinical Reasoning and Diagnostic Skills
- Gambling Behavior and Treatments
- Enhanced Recovery After Surgery
- Corneal surgery and disorders
- Sleep and related disorders
- Abdominal Surgery and Complications
- Congenital Diaphragmatic Hernia Studies
- Ophthalmology and Eye Disorders
Children's Hospital of Zhejiang University
2018-2025
Weatherford College
2023
Zhejiang University
2014-2018
First Affiliated Hospital Zhejiang University
2017
High-concentration oxygen inhalation is the primary intervention to prevent perioperative hypoxemia. However, there are concerns that this may induce an imbalance in oxidation‒reduction processes, particularly pediatric patients with compromised antioxidant defenses. This study aimed evaluate impact of varying intraoperative concentrations on oxidative stress children by analyzing plasma biomarkers, oxygenation indices, and duration surgery inhalation. Forty-five scheduled for laparoscopic...
Objective The incidence of intraoperative hypothermia remains high in pediatric patients during anesthesia and surgery even though core body temperature monitoring warming systems have been greatly improved recent years. We analyzed the risk factors outcomes neonates infants undergoing general surgery. Methods data on hypothermia, other clinical characteristics, from electronic records 1,091 (501 590 between 28 days 1 year old), who received surgery, were harvested analyzed. Intraoperative...
The definition of sepsis was updated to sepsis-3 in February 2016. However, the performance previous and new remains unclear China. This a retrospective multicenter study six intensive care unit (ICUs) from five university-affiliated hospitals compare between sepsis-1 From May 1, 2016 June 2016, 496 patients were enrolled consecutively. Data extracted electronic clinical records. We evaluated by measuring area under receiver operating characteristic curves (AUROC) predict 28-day mortality...
This retrospective study was designed to identify the incidence, outcome and analyze risk factors of perioperative pulmonary complications in children with mediastinal mass so that achieve Enhanced Recovery After Surgery(ERAS). enrolled 247 pediatric patients undergoing resection from June 2016 2022. Medical record reviewed for basic characteristics, presenting symptoms, preoperative imaging results, intraoperative data, occurrence any complications. Perioperative complication defined as...
Abstract Background: The World Health Organization (WHO) has endorsed school bystander cardiopulmonary resuscitation (CPR) training programs. But related researches in China are limited. Therefore, we conducted this study to assess CPR children and the impact of neighborhood socio-economic status (SES) on. Methods: A total 1,093 students from seven schools Zhejiang province participated study. Theoretical practical were instructor-led classes. Students completed a 10-statement questionnaire...
The risk factors, outcomes, and typical patterns of intraoperative hypothermia were studied in neonates to better guide the application insulation measures operating room. This retrospective study enrolled 401 undergoing surgery under general anaesthesia with tracheal intubation, including abdominal surgery, thoracic brain others. collected basic characteristics, such as age, sex, weight, birth gestational week, primary diagnosis American Society Anaesthesiologists (ASA) grade. Perioperative...
Abstract Procedural sedation for diagnostic examination is a common practice in children. The study aims to analyze the sedative effect and safety of intranasal dexmedetomidine combined with oral midazolam outpatient pediatric procedural across different age groups assess incidence failure. From February 2021 September 2021, children who underwent were retrospectively enrolled. divided into 4 based on age: infant group (0 1 year old), toddler (1 3 years preschool (3 6 school-age (6 12 old)....
Background: The aim of this study was to analyze the global trends sepsis research and investigate China's contribution by comparing quantity quality sepsis-related publications. Methods: Sepsis-related publications were main retrieved from Web Science online database using keywords "sepsis" or "septic shock." Bibliometric indicators, including number publications, total citation frequency, frequency per paper, h-index, type, orientation, organization, author, journal, funding support...
DEFA1/DEFA3, genes encoding human neutrophil peptides (HNP) 1-3, display wide-ranging copy number variations (CNVs) and is functionally associated with innate immunity infections. To identify potential associations between DEFA1/DEFA3 CNV hospital-acquired infections (HAIs), we enrolled 106 patients HAIs 109 controls in the intensive care unit (ICU) examined their CNVs. ranged from 2 to 16 per diploid genome all 215 critically ill patients, a median of 7 copies. In HAIs, varied 12 6, which...
Intraoperative hypothermia (core temperature <36.0°C) is common during the perioperative period and can result in adverse consequences, especially children. We aimed to determine incidence of intraoperative its risk factors pediatric patients burn surgery.In present study we enrolled 197 with injury undergoing surgical debridement skin grafting. Factors, such as total surface area (TBSA), were collected analyzed identify potential for hypothermia.The among all was 17.8%. Compared...
This study aimed to determine the incidence and evaluate risk factors outcomes of intraoperative hypothermia (IH) during general anesthesia in infants. Retrospective analysis prospectively collected data. A total 754 infants younger than 1 year old who underwent surgery under were included. Intraoperative body temperature fluctuations, surgical anesthetic data, postoperative complications, infant recorded. Logistic regression algorithms used potential factors. Among infants, 47.88% developed...
Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions.A retrospective, cohort, single center 226 patients who...
Factors influencing the length of stay (LOS) undergoing robot-assisted thoracoscopic lung surgery in setting enhanced recovery after (ERAS) protocol for pediatric patients: a retrospective study
Abstract Background The exact median effective dose (ED50) of intranasal dexmedetomidine combined with oral midazolam sedation for magnetic resonance imaging (MRI) examination in children remains unknow and the aim this study was to determine ED50 their combination. Methods This is a prospective dose-finding study. A total 53 aged from 2 months 6 years scheduled MRI February 2023 April were randomly divided into group D (to dexmedetomidine) M midazolam). dosage adjusted according modified...
We aimed to develop a predictive difficult caudal epidural blockade (pDCEB) model when ultrasound was not available and verified the role of in (CEB).From October 2018 March 2019, this study consisted three phases. First, we prospectively enrolled 202 patients scheduled undergo anesthesia assessed risk factors by binary logistic regression scoring system. Second, 87 validate it. The receiver operating characteristic (ROC) curve used evaluate performance prediction model. Youden-index...
Objective To evaluate the feasibility of developing hospital acquired pneumonia(HAP)risk warning model in critically ill patients based on genomic copy number polymorphisms(CNPs)of genes encoding human neutrophil peptides 1-3(DEFA1/DEFA3). Methods Seventy-seven HAP patients(group HAP)and 109 non-HAP matched age and sex intensive care unit(ICU)(group NHAP)were enrolled study.The CNPs DEFA1/DEFA3 was determined by real-time quantitative polymerase chain reaction after extracting DNA...
Abstract Background: Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions. Methods: A retrospective, cohort, single...
Abstract Background: Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions. Methods: A retrospective, cohort, single...
Abstract Background: Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve cooperation and quality of endoscopy. However, sedation is still not very popular some resource-limited countries regions. The purpose this study was to compare propofol-based sedated versus un-sedated CLE the value diagnosing early cancer (EGC) precancerous lesions. Methods: A retrospective, cohort, single...