A5062848955- Parvovirus B19 Infection Studies
- HIV Research and Treatment
- Cytomegalovirus and herpesvirus research
- HIV/AIDS Research and Interventions
- Herpesvirus Infections and Treatments
- HIV/AIDS drug development and treatment
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Hepatitis C virus research
- Viral-associated cancers and disorders
- Pediatric health and respiratory diseases
- Respiratory viral infections research
- Animal Disease Management and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Parasitic Infections and Diagnostics
- Cervical Cancer and HPV Research
- Biosensors and Analytical Detection
- HIV, Drug Use, Sexual Risk
- Fungal Infections and Studies
- Malaria Research and Control
- Nail Diseases and Treatments
- SARS-CoV-2 detection and testing
- Youth, Drugs, and Violence
- Antifungal resistance and susceptibility
- Adolescent Sexual and Reproductive Health
Universidade Federal do Rio Grande
2015-2025
Escola Superior de Enfermagem de Lisboa
2023
Presidio Ospedaliero
2021
Universidade Federal do Rio Grande do Sul
2013-2019
Brazilian Micro and Small Enterprises Support Service
2018
MRC Laboratory of Molecular Biology
2013
Universidade Federal de Pelotas
2010
QIMR Berghofer Medical Research Institute
2010
Objectives: To describe the molecular and epidemiological profile of HIV-1 in patients followed at University Hospital Rio Grande, Brazil. Design methods: A cross-sectional study was conducted from September to December 2002. Plasma viral RNA 85 extracted protease reverse transcriptase genes were polymerase chain reaction-amplified sequenced. Sequences subtyped examined antiretroviral resistance mutations. Laboratory data past history treatment also collected. Results: Most viruses either...
Approximately 36.7 million people were living with the human immunodeficiency virus (HIV) at end of 2016 according to UNAIDS, representing a global prevalence rate 0.8%. In Brazil, an HIV 0.24% has been estimated, which represents approximately 830,000 individuals virus. As touristic and commercial hub in Latin America, Brazil harbors elevated genetic variability, further contributed by selective pressure exerted host immune system antiretroviral treatment. Through progress next-generation...
Herpes simplex virus (HSV) infection is one of the most prevalent infectious diseases worldwide, with HSV-2 being primarily associated genital infections. believed to account for majority cases neonatal herpes, which may cause diverse complications in infected newborns. The present study sought estimate prevalence placental tissue samples and incidence umbilical cord blood newborn infants. Placental from 201 women (maternal-side fetal-side = 402 specimens) 184 samples, all collected at...
To compare the prevalence and factors associated with vertical transmission of human immunodeficiency virus 1 (HIV-1) among pregnant women treated in periods 1998-2004 2005-2011 a reference service for care HIV-infected patients southern Brazil.This was descriptive analytical study that used databases laboratories from CD4 STDs/AIDS Viral Load National Laboratory Network Brazilian Ministry Health. HIV-1-infected were selected after an active search clinical information obstetric neonatal...
Problem Herpes simplex virus 1 ( HSV ‐1) commonly causes orolabial infection, but can also infect the genital mucosa. In contrast, ‐2 is usually genital. Genital herpes transmit vertically to fetus during pregnancy. We sought estimate prevalence of ‐1/2 on maternal and fetal sides placenta. Method study Placental tissues were collected from pregnant women seen at Rio Grande University Hospital. ‐1 detected by nested PCR . Results The was, respectively, 28% 12.6% (maternal side) 29.9% 8.3%...
SUMMARY The herpes simplex virus type 2 (HVS-2) is the most prevalent infection worldwide. It a cofactor in acquisition of human immunodeficiency (HIV) and persistence papillomavirus (HPV). This study evaluated prevalence HSV-2, using polymerase chain reaction (PCR), associated factors patients treated at Federal University Rio Grande (FURG) Basic Health Units (BHU) Grande, Brazil. observed HSV-2 was 15.6%. Among 302 women studied, 158 had received assistance BHU 144 were FURG. these groups...
Coronavirus disease (COVID-19) is a pandemic caused by new coronavirus, called SARS-CoV-2. This was first identified in December 2019 and rapidly developed into challenge to the public health systems around world. In absence of vaccine specific therapies, control promotion patient are strongly dependent on rapid accurate diagnosis. review describes main laboratory approaches making diagnosis COVID-19 identifying those previously infected with
Different human immunodeficiency virus type 1 (HIV-1) subtypes may have distinct biological, immunological and pathogenic properties. Efficiency of mother-to-child transmission (MTCT) be among those properties, but few controversial results been described so far. In this study, 102 children born from HIV-1-infected mothers between 1998 2004 in the city Rio Grande, Brazil were analyzed for potential risk factors associated with MTCT. That geographic region is characterized by a high...
Paracoccidioides brasiliensis is the etiological agent of major systemic mycosis in Brazil, called paracoccidioidomycosis. Although Rio Grande do Sul considered an endemic area disease, there are few studies on ecology P. state. Therefore, this study aimed to evaluate infection horses from mesoregion Southwest Riograndense, using these animals as sentinels. Serological techniques, such double immunodiffusion agar gel (AGID) and indirect ELISA, were performed detect anti-gp43 antibody five...
Human pegivirus type 1 (HPgV-1) infection has been associated with a beneficial effect on the prognosis of human immunodeficiency virus (HIV-1)-coinfected individuals. However, mechanisms involved in this protection are not yet fully elucidated. To date, circulating HPgV-1 genotypes HIV-1-infected individuals have identified extreme south Brazil. The present study aimed to determine genotypic circulation and influence status persistence time evolution HIV-1 infection. A retrospective cohort...
Abstract Objective Estimate the prevalence of human herpesvirus type 1 HSV-1 DNA in placental samples, its incidence umbilical cord blood newborns and associated risk factors. Methods Placental biopsies were analyzed, totaling 480 from asymptomatic parturients their at a University Hospital. Nested polymerase chain reaction (PCR) gene sequencing used to identify virus; odds ratio (OR) relative (RR) performed compare factors with this condition. Results The samples was 37.5%, 27.5%....
Previous studies have demonstrated that coinfection with HPgV is a protective factor for human immunodeficiency virus (HIV)-infected patients, leading to slower disease progression, and longer survival after established disease. The present study sought estimate the prevalence of infection associated risk factors in patients harboring C or non-C HIV-1 subtypes followed-up at HU-FURG, southern Brazil. Samples from 347 HIV-1-infected subjects were subjected plasma RNA extraction, cDNA...
Recent studies have suggested that human pegivirus 1 (HPgV-1) may some pathogenic potential. In the southernmost region of Brazil, on HPgV-1 are scarce, and circulating genotypes not yet been identified. The current study aimed to evaluate prevalence among blood donors from Brazil identify involved with associated factors. A cross-sectional was conducted 281 donors, who had their plasma subjected RNA extraction, complementary DNA synthesis, detection by nested polymerase chain reaction,...
Human toxocariasis consists of chronic tissue parasitosis that is difficult to treat and control. This study aimed evaluate the action probiotic Lactobacillus acidophilus ATCC 4356 on larvae Toxocara canis effect IFN-γ cytokine parasite-host in vivo (1.109 CFU) vitro (1.106, 1.107, 1.108, 1.109 interactions. Four groups six BALB/c mice were formed: G1 - L. supplementation T. infection; G2 G3 supplementation; G4 PBS administration. Mice intragastrically suplemented with probiotics for 15 days...
Increasing evidence suggests that human papillomavirus (HPV) intratype variants (specific lineages and sublineages) are associated with pathogenesis progression from HPV infection to persistence the development of cervical cancer.This study aimed verify prevalence distribution types HPV16 in southern Brazil women normal cytology or intraepithelial lesions.HPV typing was determined by L1 gene sequencing. To identify variants, LCR E6 regions were sequenced, characteristic single nucleotide...
OBJETIVO: Determinar a frequência do Papilomavírus Humano (HPV) na placenta, no colostro e sangue cordão umbilical de parturientes seus neonatos atendidos Ambulatório Ginecologia Obstetrícia Hospital Universitário Rio Grande (RS), Brasil. MÉTODOS: Foram coletadas biópsias 150 placentas lado materno, fetal, 138 amostras 118 colostro. As placenta foram da porção central periférica. O DNA foi extraído segundo protocolo fabricante conforme referência encontrada literatura. HPV detectado pela...