A5101825311- Neurobiology and Insect Physiology Research
- Insect Resistance and Genetics
- Insect-Plant Interactions and Control
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Insect Utilization and Effects
- DNA and Nucleic Acid Chemistry
- Plant Virus Research Studies
- Antimicrobial Peptides and Activities
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced biosensing and bioanalysis techniques
- Insect Pest Control Strategies
- Bacteriophages and microbial interactions
- Environmental Toxicology and Ecotoxicology
- Identification and Quantification in Food
- CRISPR and Genetic Engineering
- Silk-based biomaterials and applications
- RNA and protein synthesis mechanisms
- Healthcare and Venom Research
- Tuberculosis Research and Epidemiology
- Silkworms and Sericulture Research
- RNA Interference and Gene Delivery
- Physiological and biochemical adaptations
University of Missouri
2016-2025
Plant (United States)
2011-2024
Nanjing Agricultural University
2022-2024
Columbia College - Missouri
2008-2024
Planta
2024
Shanghai Public Health Clinical Center
2021-2022
Fujian Agriculture and Forestry University
2016-2020
Shandong University
2008-2020
South China Normal University
2017
Hunan Agricultural University
2013-2014
Abstract G-quadruplex (G4) structure is a nucleic acid secondary formed by guanine-rich sequences, playing essential roles in various biological processes such as gene regulation and environmental stress adaptation. Although prokaryotes growing at high temperatures have higher GC contents, the pattern of G4 associated with content variation thermal adaptation remains elusive. This study analyzed 681 bacterial genomes to explore role structures Our findings revealed strong positive...
Abstract G-quadruplex (G4) structures have been predicted in the genomes of many organisms and proven to play regulatory roles diverse cellular activities. However, there is little information on evolutionary history distribution characteristics G4s. Here, whole-genome potential G4s were studied 37 evolutionarily representative species. During evolution, number, length, density generally increased. Immunofluorescence seven species confirmed G4s’ presence pattern. tended cluster chromosomes...
Juvenile hormone (JH) regulates many developmental and physiological events in insects, but its molecular mechanism remains conjectural. Here we report that genetic ablation of the corpus allatum cells Drosophilaring gland (the JH source) resulted deficiency, pupal lethality precocious enhanced programmed cell death (PCD) larval fat body. In body JH-deficient animals, Dronc Drice,two caspase genes are crucial for PCD induced by molting 20-hydroxyecdysone (20E), were significantly...
Background Bursicon is a heterodimer neuropeptide composed of two cystine knot proteins, bursicon α (burs α) and β β), that elicits cuticle tanning (melanization sclerotization) through the Drosophila leucine-rich repeats-containing G protein-coupled receptor 2 (DLGR2). Recent studies show both subunits also form homodimers. However, biological functions homodimers have remained unknown until now. Methodology/Principal Findings In this report, we in melanogaster induced expression genes...
Guanine-rich and cytosine-rich DNA can form four-stranded secondary structures called G-quadruplex (G4) i-motif, respectively. These widely exist in genomes play important roles transcription, replication, translation protection of telomeres. In this study, G4 i-motif were identified the promoter transcription factor gene BmPOUM2, which regulates expression wing disc cuticle protein (BmWCP4) during metamorphosis. Disruption structure by base mutation, anti-sense oligonucleotides (ASOs) or...
The diamondback moth, Plutella xylostella is a cosmopolitan pest that has evolved resistance to all classes of insecticide, and costs the world economy an estimated US $4-5 billion annually. We analyse patterns variation among 532 P. genomes, representing worldwide sample 114 populations. find evidence suggests South America geographical area origin this species, challenging earlier hypotheses Old-World origin. Our analysis indicates experienced three major expansions across world, mainly...
Abstract Background Krüppel homolog 1 (Kr-h1) is a critical transcription factor for juvenile hormone (JH) signaling, known to play key role in regulating metamorphosis and adult reproduction insects. Kr-h1 can also be induced by molting 20-hydroxyecdysone (20E), however, the underlying mechanism of 20E-induced expression remains unclear. In present study, we investigated molecular induction 20E reproductive system model lepidopteran insect, Bombyx mori . Results Developmental...
Abstract Background Nuclear transport factor 2 and small GTPase Ran participate in the nucleo-cytoplasm of macromolecules, but their function 20-hydroxyecdysone (20E) signal transduction pathway are not well known. Results A 703 bp encoding Ntf2 a 1233 full-length cDNAs were cloned from Helicoverpa armigera , named Ha-Ntf2 Ha-Ran respectively. Northern blot immunoblotting revealed that had an obviously higher expression levels head-thorax integument metamorphically committed larvae. In...
Abstract In insects, neuropeptides play important roles in the regulation of multiple physiological processes by binding to their corresponding receptors, which are primarily G protein-coupled receptors (GPCRs). The genes encoding and associated GPCRs rice stem borer Chilo suppressalis were identified a transcriptomic analysis used identify potential targets for disruption protection crops. Forty-three candidate found encode neuropeptide precursors all known insect except...
Double-stranded DNAs are usually present in the form of linear B-form double-helix with base pairs adenine (A) and thymine (T) or cytosine (C) guanine (G), but G-rich DNA can four-stranded G-quadruplex (G4) structures, which plays important roles transcription, replication, translation protection telomeres. In this study, a RNA recognition motif (RRM)-containing protein, BmLARK, was identified demonstrated to bind G4 structures promoters transcription factor BmPOUM2 other three unidentified...
Abstract Parasitoid wasps represent a large proportion of hymenopteran species. They have complex evolutionary histories and are important biocontrol agents. To advance parasitoid research, combination Illumina short‐read, PacBio long‐read Hi‐C scaffolding technologies was used to develop high‐quality chromosome‐level genome assembly for Pteromalus puparum , which is an pupal endoparasitoid caterpillar pests. The has aided in studies venom detoxification genes. assembled size 338 Mb with...
Ostrinia furnacalis is one of the most important pests on maize. O. larvae are frequently exposed to temperature challenges such as high in summer and cold winter natural environment. High low stress, like any abiotic impairs physiology development insects. Up now, there limited information about gene regulation signaling pathways related stress response furnacalis. High-throughput sequencing transcriptome provides a new approach for detecting immune genes under stresses In present study,...
DNA methylation is an important epigenetic modification. However, the regulations and functions of insect intragenic remain unknown. Here, we demonstrate that a regulatory mechanism involving controls ovarian embryonic developmental processes in Bombyx mori. In B. mori, found near transcription start site (TSS) genes. By promoter activity analysis, observed 5′ UTR enhances gene expression. Moreover, methyl-DNA-binding domain protein 2/3 (MBD2/3) binds to methyl-CpG fragment recruits...
The ectoparasitic wasp Habrobracon hebetor (Hymenoptera, Braconidae) can parasitize various species of lepidopteran pests. To maximize its potential for biological control, it is necessary to investigate gene function through genome engineering.
Climate change is likely to have marked ecological effects on terrestrial ecosystems, including the activities of insect pests. Most attention has focused increasing geographical ranges pests; however, if extrinsic factors enhance their thermotolerance, populations may express increased voltinism and longer daily annual activity periods. These changes in pest potential for severe consequences, crop losses decreased food security at global level. The brown planthopper (BPH) Nilaparvata lugens...
Diet composition is a critical determinant of lifespan, and nutrient imbalance detrimental to health. However, how nutrients interact with genetic factors modulate lifespan remains elusive. We investigated diet influences mitochondrial ATP synthase subunit d (ATPsyn-d) in modulating Drosophila. ATPsyn-d knockdown extended females fed low carbohydrate-to-protein (C:P) diets but not the high C:P ratio diet. This extension was associated increased resistance oxidative stress; transcriptional...
Cytochrome P450 monooxygenases have been proven to be associated with high resistance in Bemisia tabaci B biotype (Middle East-Asia Minor 1 genetic group) and Q (Mediterranean the neonicotinoid class of insecticides. In this study, RNA interference (RNAi) effects on CYP6CM1 gene expression, mortality pesticide-detoxifying ability between B. biotypes were compared an attempt provide a basis for potential RNAi application management pest.Double-stranded RNAs (dsRNAs) genes corresponding...