- Adipose Tissue and Metabolism
- Molecular Sensors and Ion Detection
- Sex and Gender in Healthcare
- Colorectal Cancer Treatments and Studies
- Millimeter-Wave Propagation and Modeling
- Biosensors and Analytical Detection
- GDF15 and Related Biomarkers
- Electrochemical Analysis and Applications
- Advanced Chemical Sensor Technologies
- Glioma Diagnosis and Treatment
- Vitamin D Research Studies
- Electrochemical sensors and biosensors
- Dendrimers and Hyperbranched Polymers
- Protein Interaction Studies and Fluorescence Analysis
- Photonic and Optical Devices
- Radio Frequency Integrated Circuit Design
- Electron Spin Resonance Studies
- Gender Roles and Identity Studies
- Cancer-related gene regulation
- Bone Metabolism and Diseases
- Peroxisome Proliferator-Activated Receptors
- Pesticide Exposure and Toxicity
- Electrocatalysts for Energy Conversion
- Genetics and Neurodevelopmental Disorders
- Analytical Chemistry and Sensors
University of California, Los Angeles
2021-2025
Shenzhen University
2023-2024
Yangzhou University
2023
Jiangnan University
2020
Wuxi Fourth People's Hospital
2020
UCLA Jonsson Comprehensive Cancer Center
2019
Sex differences in physiology and disease mammals result from the effects of three classes factors that are inherently unequal males females: reversible (activational) gonadal hormones, permanent (organizational) cell-autonomous sex chromosomes, as well genes driven by these factors. Often, act together to cause specific phenotypes, but relative contribution each interactions among them remain unclear. Here, we used four core genotypes (FCG) mouse model with or without hormone replacement...
The first fluorescent sensor based on the indicator displacement assay (IDA) for on-site determination of etomidate.
Starting at middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) fat undergo extensive adipogenesis during age. Thus, despite the low turnover rate of adipocytes young adults, is unlocked Transplantations quantitatively showed APCs middle-aged exhibited high adipogenic capacity cell-autonomously. Single-cell RNA sequencing identified a distinct APC population, committed...
Intermolecular proton transfer from a flavonol-based probe to the arginine (Arg222) in drug site 1 of human serum albumin triggers an unusual red-shifted ratiometric fluorescence response, which can be applied point-to-care diagnosis hypoalbuminemia.
Abstract Sex differences in physiology and disease mammals result from the effects of three classes factors that are inherently unequal males females: reversible (activational) gonadal hormones, permanent (organizational) cell-autonomous sex chromosomes, as well genes driven by these factors. Often, act together to cause specific phenotypes, but relative contribution each interactions among them remain unclear. Here, we used Four Core Genotypes (FCG) mouse model with or without hormone...
Vitamin D is a lipid soluble vitamin that mostly used to treat bone metabolism-related diseases. In this study, the effect of Cd toxicity in vitro on osteogenic differentiation derived from BMSCs and alleviating lα, 25-(OH)2D3 were investigated. Cell index real time was monitored using Real-time cell analyzer (RTCA) system. The activity alkaline phosphatase (ALP), calcified nodules distribution Runx2 protein detected ALP staining, alizarin red immunofluorescence, respectively. Furthermore,...
Adipose tissue regulates energy homeostasis and metabolic function, but its adaptability is impaired in obesity. In this study, we investigate the impact of acute PPARγ agonist treatment obese mice find significant transcriptional remodeling cells stromal vascular fraction (SVF). Using single-cell RNA sequencing, profile SVF inguinal epididymal adipose following rosiglitazone an induction ribosomal factors both progenitor preadipocyte populations, while expression reduced with Notably, a...
This study aimed to identify potential genes and transcription factors involved in postradiation cognitive dysfunction using bioinformatics analysis.Bioinformatics tools were used differentially expressed mRNAs between dysfunctional control tissue. The GSE115735 dataset containing mRNA expression profiles was downloaded from the Gene Expression Omnibus database. data corresponded three hippocampus brain lateral ventricles mice controls. two groups identified, protein-protein interaction...