A5030511639- Helicobacter pylori-related gastroenterology studies
- Pain Mechanisms and Treatments
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Botulinum Toxin and Related Neurological Disorders
- Anesthesia and Pain Management
- Neuropeptides and Animal Physiology
- Nerve injury and regeneration
- Veterinary medicine and infectious diseases
- Vector-borne infectious diseases
- Eosinophilic Esophagitis
- Eicosanoids and Hypertension Pharmacology
- Microbial Metabolites in Food Biotechnology
- Gastroesophageal reflux and treatments
- Galectins and Cancer Biology
- Nitric Oxide and Endothelin Effects
- Pharmacological Effects of Natural Compounds
- Mosquito-borne diseases and control
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Otolaryngology and Infectious Diseases
- Antibiotic Use and Resistance
- Receptor Mechanisms and Signaling
- Gastrointestinal disorders and treatments
- Neonatal and Maternal Infections
- Musculoskeletal pain and rehabilitation
Kaohsiung Medical University
2012-2024
Kaohsiung Medical University Chung-Ho Memorial Hospital
2010-2024
NIHR Leeds Musculoskeletal Biomedical Research Unit
2024
University of Leeds
2024
Chengdu Women's and Children's Central Hospital
2018
Christie's
2016
Zhongshan Hospital of Xiamen University
2016
Creative Commons
2016
Science Council
2016
I-Shou University
2010-2016
ObjectivesThis prospective study was designed to determine the efficacy of a levofloxacin-based rescue therapy for Helicobacter pylori infection after failure standard triple therapies. We also surveyed predictors this therapy.
Abstract Objectives: Polymicrobial bloodstream infection (BSI) is a critical condition and has been increasingly reported; however, the authors were unable to find an emergency department (ED) patient‐based study in literature. Methods: A retrospective matched case–control with ratio of 1:3 among patients polymicrobial BSIs ED was conducted. The case group aged > 16 years BSIs. Patients for age sex monomicrobial sampled as control group. Demographic information, underlying conditions,...
Background: Cilostazol is an antiplatelet agent with vasodilating, endothelial function restoration, and anti-inflammatory effects. This study aims to investigate the efficacy of oral cilostazol for preventing development diabetic peripheral neuropathy (DPN). Materials Methods: Ninety adult male Sprague-Dawley rats were divided into five groups: 1) naïve (control); 2) (DM); 3) DM receiving 10 mg/kg (cilo-10); 4) 30 (cilo-30); 5) 100 (cilo-100). Hindpaw responses thermal mechanical stimuli...
The current study was to investigate the interaction between Helicobacter pylori and human dendritic cells (DCs). Whether impaired DC function can influence outcome of H. infections. Human monocyte-derived DCs (MDDCs) from five gastric cancer patients nine healthy controls were stimulated with pylori. Maturation markers MDDC examined by flow cytometry. IL-10 TNF-α released MDDCs IL-17 produced T measured ELISA. Regulatory signaling pathways ELISA, western blotting, chromatin...
ABSTRACT The severity of skin and soft tissue infections caused by group A Streptococcus (GAS) is variable, there are only a limited number studies evaluating the characteristics these in literature. From May 2005 to November 2007, 73 patients with were included this study. Among patients, 34 (46.6%) had invasive diseases. Diabetes mellitus, alcoholism, hypertension most common underlying disorders. overall mortality rate was 6.8%, elderly predisposed ( P < 0.001). Neutrophil percentages...
Sixty-three rifampicin-resistant (Rif r ) isolates of Mycobacterium tuberculosis from Kaohsiung, Taiwan, were analysed for mutations in the core region (69 bp, codons 511–533) rpoB gene. Some 84.1 % (53/63) resistant showed this region, especially 531 (41.5 %), 526 (18.9 516 (15.1 %) and 533 (7.5 %). Five novel alleles a total 16 different types identified Rif isolates. Ten (15.9 exhibited no . Also, they did not show another 365 bp fragment (codons 99–220) The agar proportion method was...
Background. The suppression of Helicobacter pylori (H. pylori) decreases H. pylori-related diseases. probiotics have an inhibitory effect on pylori. Aim. We investigated the effects long-term use yogurt based Mongolian gerbils' model. Materials and Methods. Yogurt (containing a supplement Lactobacillus acidophilus, Bifidobacterium lactis, etc.) was used. Forty-six gerbils were divided into five groups. All groups inoculated with for 5 to 8 weeks. given as follows: Group (Gr.) A: from 1st 4th...
Currently, Helicobacter pylori (H. pylori) infection is confirmed to correlate with chronic gastritis, peptic ulcer disease, Mucosa Associated Lymphoid Tissue (MALT)-lymphoma, precancerous changes in the stomach (atrophy, intestinal metaplasia), and gastric cancer. At same time, H. eludes immunological response evoked by host. This has local production systemic diffusion of proinflammatory cytokines, which may influence remote organic systems result extragastric manifestations [1] (Table...
Because Helicobacter pylori (H pylori) would cause carcinogenesis of the stomach, we need sufficient information for deciding on an appropriate strategy eradication. Many factors affect efficacy eradication including antimicrobial resistance (especially clarithromycin resistance) and CYP2C19 polymorphism. This study was to survey efficiency gastric juice detecting H infection, resistance, polymorphism.The specimens were collected from all patients while receiving gastroscopy. DNA extracted...
Intrathecal lidocaine reverses tactile allodynia after nerve injury, but whether neuropathic pain is attenuated by intrathecal pretreatment uncertain.Sixty six adult male Sprague-Dawley rats were divided into three treatment groups: (1) sham (Group S), which underwent removal of the L6 transverse process; (2) ligated L), left L5 spinal ligation (SNL); and (3) pretreated P), SNL was with 2% (50 μl). Neuropathic assessed based on behavioral responses to thermal mechanical stimuli. Expression...
Q fever is serologically cross-reactive with other intracellular microorganisms. However, studies of the serological status Mycoplasma pneumoniae and Chlamydophila during are rare. We conducted a retrospective study M. C. by enzyme-linked immunosorbent assay (ELISA), method widely used in clinical practice, 102 cases acute fever, 39 scrub typhus, 14 murine typhus. The seropositive (57.8%, 7.7%, 0%, p<0.001) seroconversion rates (50.6%, 8.8%, IgM, but not IgG IgG/IgM, were significantly...
Background The clinical characteristics of Q fever are poorly identified in the tropics. Fever with pneumonia or hepatitis dominant presentations acute fever, which exhibits geographic variability. In southern Taiwan, is located a tropical region, role community-acquired (CAP) has never been investigated. Methodology/Principal Findings During study period, May 2012 to April 2013, 166 cases adult CAP and 15 were prospectively Cultures specimens, urine antigen tests for Streptococcus...
Glycine receptors (GlyRs) are involved in the development of spinal pain sensitization. The GlyRα3 subunit has recently emerged as a key factor inflammatory pathways cord dorsal horn (DH). Our study is to identify extent location and cell types expressing different GlyR subunits root ganglion (DRGs). To tease out possible actions GlyRs on transmission, we investigate effects produced by acute behavioral testing using prostaglandin E2 (PGE2) intrathecal injection models. Furthermore, changes...
Background and Objective: Our previous study demonstrated that consistent treatment of oral cilostazol was effective in reducing levels painful peripheral neuropathy streptozotocin-induced type I diabetic rats. As is characterized by hyperglycemia-induced nerve damage the periphery, this aims to examine neuropathology as well effects treatments on integrity small fibers Materials Methods: A total ninety adult male Sprague-Dawley rats were divided into following groups: (1) naïve (control)...