A5100379789- Multicomponent Synthesis of Heterocycles
- Catalytic C–H Functionalization Methods
- Synthesis and biological activity
- Cancer Immunotherapy and Biomarkers
- Synthesis and Characterization of Pyrroles
- Synthesis and Biological Evaluation
- Microwave-Assisted Synthesis and Applications
- Adsorption and biosorption for pollutant removal
- Synthesis and Reactivity of Heterocycles
- Chemical Synthesis and Reactions
- Synthesis and Catalytic Reactions
- Chemical Synthesis and Analysis
- Asymmetric Synthesis and Catalysis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Cyclopropane Reaction Mechanisms
- Membrane Separation Technologies
- Surfactants and Colloidal Systems
- Synthetic Organic Chemistry Methods
- Advanced oxidation water treatment
- Quinazolinone synthesis and applications
- Synthesis and Characterization of Heterocyclic Compounds
- Aerogels and thermal insulation
- Oxidative Organic Chemistry Reactions
- Synthesis and Reactions of Organic Compounds
- Nanomaterials for catalytic reactions
Anhui Polytechnic University
2016-2025
South China Agricultural University
2021-2025
University of Science and Technology Beijing
2022-2025
Shanghai Academy of Spaceflight Technology
2024-2025
Shandong University
2012-2024
Ministry of Agriculture and Rural Affairs
2024
Nanjing Agricultural University
2021-2024
Xi'an Polytechnic University
2024
University of Shanghai for Science and Technology
2024
Chongqing Medical University
2024
With the increasing of aging population and consumption high-fat diets (HFD), incidence Alzheimer's disease (AD) has skyrocketed. Natural antioxidants show promising potential in prevention AD, as oxidative stress neuroinflammation are two hallmarks AD pathogenesis. Here, we showed that quinic acid (QA), a polyphenol derived from millet, significantly decreased HFD-induced brain levels Aβ p-Tau. Examination gut microbiota suggested improvement composition HFD mice after QA treatment....
Abstract The proanthocyanidins in three foods (pinto beans, plums and cinnamon) were studied with electrospray ionization (ESI) mass spectrometry (MS) the negative mode following separation by normal‐phase high‐performance liquid chromatography. MS/MS analysis demonstrated that major ions derived from heterocyclic ring fission retro‐Diels–Alder reaction of flavan‐3‐ol provided information about hydroxylation pattern type interflavan bond. connection sequence oligomers was identified through...
Resources and environment carrying capacity is the key to achieving Sustainable Development Goals (SDGs). This study takes SDGs as research perspective, taking Southwest Guangxi Karst-Beibu Gulf a typical area, counties unit, creates three-dimensional balance model of resource environmental capacity, carried out comprehensive evaluation analysis in this area. It reveals warning grade different regions transitional space mountains, rivers seas, provides scientific basis for construction...
An efficient and practical tandem reaction of 4-arylidene isoxazol-5-ones with enamino esters catalyzed by an inexpensive copper salt has been established in a ball mill. This innovative approach yields diverse array structurally novel pyrrole-2-carboxylic acids, showing excellent tolerance toward different functional groups. By integrating spiroannulation ring-opening aromatization processes, this protocol introduces facile cost-effective strategy for synthesizing highly functionalized...
A rapid and efficient method for the preparation of various poly-substituted quinolines has been developed through Friedländer condensation 2-aminoarylketone or 2-aminoarylaldehyde with carbonyl compounds in presence p-toluene sulphonic acid, which was achieved by both microwave irradiation conventional heating under solvent-free conditions.
Scavenger receptors are a superfamily of membrane-bound that recognize both self and nonself targets. receptor class A (SR-A) has five known members (SCARA1 to -5 or SR-A1 -A5), which type II transmembrane proteins form homotrimers on the cell surface. SR-A various ligands involved in multiple biological pathways. Among them, SCARA5 can function as ferritin receptor; however, interaction between not been fully characterized. Here, we determine crystal structures C-terminal scavenger...
Objectives Immune checkpoint inhibitors (ICIs) alone or combined with other antitumor agents are largely used in lung cancer patients, which show both positive effects and side particular subjects. Our study aims to identify biomarkers that can predict response immunotherapy risk of effects, may help us play a role minimize the adverse clinical practice. Methods We retrospectively collected data from patients advanced non-small cell (NSCLC) treated ICIs at our center. Patients who received...
A novel and flexible domino reaction of aurones with pyridin-2-yl active methylene compounds promoted by I2/BF3 has been developed to afford spirodihydroindolizines indolizines in a controllable manner. When the was performed 1,2-dichloroethane at 80 °C, variety were obtained, whereas it almost exclusively provided series when mixed solvent N,N-dimethylformamide relatively higher temperature 100 °C. Being metal-free, excellent product selectivity, high atom economy, good functional group...
To improve the conversion rate of carbon dioxide (CO2) to methane (CH4) in a microbial electrochemical system (MES), zeolitic imidazolate framework ZIF-67(Co) with electron storage properties was first grown situ on MIL-100(Fe) excellent CO2 adsorption by hydrothermal method. The obtained binary core–shell MIL@ZIF material then adsorbed felt cathode grow biofilms composed electroactive microorganisms for characterization and testing an MES. This exhibited CH4 production 0.42 mmol LR–1 d–1,...
A new cyclization pattern between arylidene isoxazolones and enamino esters has been demonstrated, efficiently affording various structurally novel cyclopentenyl spiroisoxazolones with high chemoselectivity in a ball mill. Interestingly, the diastereoselectivity...
N-Iodosuccinimide-promoted cascade reactions of arylidene isoxazolones with amidines in p-xylene were accomplished, affording 5-acylimidazoles good to excellent yields. Interestingly, when the performed by employing acetonitrile as solvent, 4-acylimidazoles efficiently obtained. Mechanistic studies indicate that formation imidazolyl and acyl moieties may undergo a spiroannulation-ring opening aromatization-hydrolysis reaction sequence. Based on this solvent-regulated tandem strategy,...
A novel NIS-promoted domino reaction of alkylidene oxindoles with 2-(pyridin-2-yl)acetate derivatives has been established, enabling the efficient and straightforward synthesis a vast variety highly functionalized indolizines via sequential spiroannulation ring-opening aromatization processes. The protocol features mild conditions, broad substrate scope, high efficiency, scalability, applicability for preparation CF3-containing indolizines. Furthermore, functional groups in indolizine...
Abstract N ‐carboxymethyl chitosans ( ‐CMC) were synthesized from chitosan in water with chloroacetic acid instead of comparatively expensive glyoxylic acid. The optimal reaction conditions 90°C and 4 h a ratio to 5 : 1(w/w). degree substitution product exceeded 1.32. characterized by XRD, FTIR, 1 H‐NMR, the solubility isoelectric point ‐CMC different degrees determined. FTIR H‐NMR data has confirmed that occurred on amino groups. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011