A5088778974- Optical Imaging and Spectroscopy Techniques
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Advanced Fluorescence Microscopy Techniques
- Optical Polarization and Ellipsometry
- Hemodynamic Monitoring and Therapy
- Infrared Thermography in Medicine
- Spectroscopy Techniques in Biomedical and Chemical Research
- Non-Invasive Vital Sign Monitoring
- Functional Brain Connectivity Studies
- Glaucoma and retinal disorders
- Mechanical Circulatory Support Devices
- Photonic and Optical Devices
- Cell Image Analysis Techniques
- Heart Rate Variability and Autonomic Control
- EEG and Brain-Computer Interfaces
- Digital Holography and Microscopy
- Platelet Disorders and Treatments
- Advanced MEMS and NEMS Technologies
- Blood properties and coagulation
- GaN-based semiconductor devices and materials
- Retinal and Macular Surgery
- Semiconductor Lasers and Optical Devices
- Advanced Surface Polishing Techniques
- Photonic Crystals and Applications
National Yang Ming Chiao Tung University
2016-2025
Wan Fang Hospital
2024
National Taiwan University Hospital
2024
Taipei Medical University
2024
National Yang Ming University Hospital
2010-2019
First Hospital of Jilin University
2019
Jilin University
2019
National Taiwan University
2000-2011
National Taipei University
2010
Industrial Technology Research Institute
2005-2008
Owing to the superior properties of silicon carbide (SiC), such as higher breakdown voltage, thermal conductivity, operating frequency, temperature, and saturation drift velocity, SiC has attracted much attention from researchers industry for decades. With advances in material science processing technology, many power applications new smart energy vehicles, converters, inverters, supplies are being realized using devices. In particular, MOSFETs generally chosen be used a device due their...
The drug susceptibility of leukemia cells in whole blood is evaluated by using extreme-throughput imaging flow cytometry with deep learning.
An ensemble empirical mode decomposition (EEMD)-based approach was developed to extract steady-state visual evoked potentials (SSVEPs) for wireless handling of a small robot car. Three stimuli, flickering at 13, 14, and 15 Hz, were displayed on liquid crystal display monitor induce user's SSVEPs. The induced SSVEPs used control three movement functions (forward, left, right) the Users gazed one chosen stimulus time, SSVEP recognized activate desired function. In this paper, all subjects...
The aims of this study were to examine the effect implant neck design and cortical bone thickness using 3D finite element analysis analyse stability clinical evidence based on micromotion principal stress. Four commercial dental implants for a type IV maxillary segments created. Various parameters considered, including osseointegration condition, loading direction thickness. Micromotion stresses used evaluate failure overloading, respectively. It was found that maximum stress peri-implant...
Optical time-stretch microscopy has recently attracted intensive attention for its capability of acquiring images at an ultrahigh frame rate. Unfortunately, achievable rate is limited by the requirement having no overlap between consecutive frames, which leads to a tradeoff (pulse repetition rate) and amount temporal dispersion used optical image serialization. In this paper, we demonstrate compressive sensing on platform overcome (time stretch) achieve 50 times higher than conventional...
Complete removal of brain tumor is the most interest to a surgeon because resection area directly relates recurrence rate. Although there are many biomedical imaging modalities applied locate positions tumors, they lack spatial resolution precisely delineate boundary between and normal tissues also inconvenient be used intraoperatively. This study aims examine feasibility label-free, polarization-sensitive optical coherence tomography (PS-OCT) for distinguishing tumors from tissues. Ex vivo...
In neurosurgery, accurately identifying brain tumor tissue is vital for reducing recurrence. Current imaging techniques have limitations, prompting the exploration of alternative methods. This study validated a binary hierarchical classification tissues: normal tissue, primary central nervous system lymphoma (PCNSL), high-grade glioma (HGG), and low-grade (LGG) using transfer learning. Tumor specimens were measured with optical coherence tomography (OCT), MobileNetV2 pre-trained model was...
We characterized and imaged dental calculus using swept-source optical coherence tomography (SS-OCT). The refractive indices of enamel, dentin, cementum, were measured as 1.625 ± 0.024, 1.534 0.029, 1.570 0.021, 2.097 0.094, respectively. Dental leads strong scattering properties, thus, the region can be identified from enamel with SS-OCT imaging. An extracted human tooth is covered gingiva tissue an in vitro sample for tomographic
The prefrontal cortex (PFC) is thought to play an important role in "higher" brain functions such as personality and emotion that may associated with several gender-related mental disorders. In this study, the gender effects of functional connectivity, cortical lateralization significantly differences PFC were investigated by using resting-state optical tomography (fOT) measurement. A total forty subjects including twenty healthy male female adults recruited for study. results, hemoglobin...
On-site instant determination of benign or malignant tumors for deciding the types resection is crucial during pulmonary surgery. We designed a portable spectral-domain optical coherence tomography (SD-OCT) system to do real-time scanning intraoperatively distinction fresh tumor specimens in lung. A total 12 ex vivo lung from six patients were enrolled. Three diagnosed with invasive adenocarcinoma (IA), while others benign. After OCT-imaged reconstruction, we compared qualitative morphology...
Although Monte Carlo simulations of light propagation in full segmented three-dimensional MRI based anatomical models the human head have been reported many articles. To our knowledge, there is no patient-oriented simulation for individualized calibration with NIRS measurement. Thus, we offer an approach brain modeling on image segmentation process vivo T1 to investigate measurement simulation.In this study, modeled 3D as five layers structure. The behavior photon migration was studied...
Survival prediction is highly valued in end-of-life care clinical practice, and patient performance status evaluation stands as a predominant component survival prognostication. While current tools are limited to their subjective nature, the advent of wearable technology enables continual recordings patients' activity has potential measure objectively. We hypothesize that wristband actigraphy monitoring devices can predict in-hospital death end-stage cancer patients during time hospital...
Abstract Migraine is a common and complex neurovascular disorder. Clinically, the diagnosis of migraine mainly relies on scales, but degree pain too subjective to be reliable indicator. It even more difficult diagnose medication-overuse headache, which can only evaluated by whether symptom improved after medication adjustment. Therefore, an objective classification system assist doctors in making accurate needed. In this research, 13 healthy subjects (HC), 9 chronic (CM), 12 headache (MOH)...
Verbal fluency tests (VFTs) are widely used frontal lobe neuropsychological tests. They have been frequently in various functional brain mapping studies. There two versions of VFTs based on the type cue: letter task (LFT) and category (CFT). However, fundamental aspects connectivity across frontotemporal regions during not elucidated. In this study, we hypothesized that differences cortical over left right may be observed by means multichannel near-infrared spectroscopy (fNIRS) performance...
This article presents a chip-scale package (CSP) with conformal and uniform structures for white light-emitting diodes used in lighting backlight unit (BLU) applications. The CSP produce higher light extraction efficiency lower assembly-dependent packaging compared conventional surface-mounted devices (SMDs). Simulation results show that SMDs, the luminous of is 8.81% applications 9.43% BLU likely due to loss bowl SMDs. Moreover, CSPs phosphor structure exhibit low assembly dependence...
A polarization-sensitive optical coherence tomography (PSOCT) system using a femtosecond-laser as the broadband light source is implemented with axial resolution of 5 µm in free space. Through design path-length difference between two polarization inputs and modulation one inputs, PSOCT images various input output combinations can be distinguished simultaneously collected. The then used for vitro scanning myocardium tissues normal infarcted rat hearts. destruction birefringence nature fiber...
A driving scheme using a pair of differential voltages (Vx, Vy) over bias voltage is proposed to linearize the dc characteristic (angle versus voltage) two-axis MEMS scanner. The micromirror has gimbal-less structure and driven by vertical comb-drive actuators in conjunction with leverage mechanism. At an optimal 53 V, linear optical scan range ±3.2° achieved experimentally both x y directions ranging from −10 V + 10 V.