A5103032355- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Essential Oils and Antimicrobial Activity
- Synthesis and biological activity
- Listeria monocytogenes in Food Safety
- Natural Antidiabetic Agents Studies
- Microbial Inactivation Methods
- Crystallography and molecular interactions
- Ethnobotanical and Medicinal Plants Studies
- Nanocomposite Films for Food Packaging
- Crystal structures of chemical compounds
- Phytochemicals and Antioxidant Activities
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Helicobacter pylori-related gastroenterology studies
- Wnt/β-catenin signaling in development and cancer
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Biological Activities
- Metal-Organic Frameworks: Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Magnetism in coordination complexes
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects of Medicinal Plants
- Inflammatory Bowel Disease
- Organometallic Compounds Synthesis and Characterization
Khyber Medical University
2025
University of Sargodha
2021-2025
University of Haripur
2020-2024
University of Swabi
2016-2024
Hazara University
2022-2024
Khyber Teaching Hospital
2016-2024
Birla Institute of Technology and Science - Hyderabad Campus
2024
University of Malakand
2011-2023
Jamia Hamdard
2015-2023
Gomal University
2023
Abstract Electrolyzed water (EW) has gained immense popularity over the last few decades as a novel broad‐spectrum sanitizer. EW can be produced using tap with table salt singular chemical additive. The application of is sustainable and green concept several advantages traditional cleaning systems including cost effectiveness, ease application, effective disinfection, on‐the‐spot production, safety for human beings environment. These features make it an appropriate sanitizing system use in...
Carvacrol is present abundantly in the essential oils of many medicinal plants and well known for its numerous biological activities. Since partial solubility water physicochemical instability limits industrial uses, study was performed to prepare a carvacrol nanoemulsion (CANE) using an ultrasonication technique further evaluation anticancer potential against human lung adenocarcinoma A549 cells. The formulation optimized by varying polysorbate 80 ratios characterized dynamic light...
Bacterial resistance to antibiotics poses a serious threat cure diseases associated with microbial infection. Among the resistant bacteria, extended-spectrum β-lactamase (ESBL)-producing bacteria are most concerned one as they encode enzyme that confers β-lactam antibiotics. The present study was carried out determine antimicrobial potential and principle mechanism of action carvacrol against ESBL Escherichia coli isolated from ascitic fluid patient having urinary tract infection (UTI)....
Triterpenes possess anti-inflammatory and anti-nociceptive effects. In this study activities of Asparacosin A were evaluated` using in-vitro cyclooxygenases 1 2 (COX-1/2) inhibition assays. Moreover assessed in-vivo by carrageenan-induced paw edema test, xylene-induced ear tests, acetic acid-induced writhing formalin tests. Additionally molecular docking was conducted to elucidate the binding mechanism compound correlate findings with in-silico data. Oral administration at doses 10, 20...
Rationale: The present study reports the multifunctional anticancer activity against B16F10 melanoma cancer cells and bioimaging ability of fluorescent nitrogen-phosphorous-doped carbon dots (NPCDs). Methods: NPCDs were synthesized using a single-step, thermal treatment characterized by TEM, XPS, fluorescence UV-Vis spectroscopy, FTIR analysis. efficacy was confirmed cell viability assay, morphological evaluation, live-dead mitochondrial potential ROS production, RT-PCR, western-blot...
Abstract A series of fifteen hybrid analogs ( 1 – 15 ) based on benzimidazole bearing triazole skeleton were synthesized and evaluated for in vitro AChE BuChE inhibition profile. All the newly afforded scaffolds showed moderate to good activity having IC 50 values ranging from 0.40 ± 0.05 19.60 μM against 1.50 0.10 23.30 0.50 comparison Donepezil (IC = 0.016 0.12 AChE), 4.5 0.11 BuChE) as reference drug. It was concluded structure–activity relationship (SAR) studies that groups strong...
The 7-quinolinyl-bearing triazole analogs were synthesized (1d-19d) and further assessed in vitro for their inhibitory profile against α-amylase andα-glucosidase. entire showed a diverse range of activities having IC50 values between 0.80 ± 0.05 µM to 40.20 0.70 (α-amylase) 1.20 0.10 43.30 (α-glucosidase) under the positive control acarbose (IC50 = 10.30 0.20 µM) 9.80 as standard drug. Among scaffolds, seven scaffolds 12d, 10d, 8d, 9d, 11d, 5d, 14d excellent α-glucosidase potentials with...
Saponins isolated from plant sources have a number of traditional and industrial applications. pharmacological effects like anti-inflammatory, molluscicidal, antimicrobial, antispasmodic, antidiabetic, anticancer, anticonvulsant, anthelmintic, antitussive cytotoxic activities. The current work describes the anthelmintic activities crude saponins Achillea Wilhelmsii Teucrium Stocksianum as these plants are rich with saponins. Brine shrimp activity was determined by Meyer et al. (1982) at test...
Purpose. Rosmarinus officinalis, traditionally known as rosemary, has been widely used in traditional medicines and long the herb of remembrance. However, few studies have investigated effects non-volatile components rosemary on central nervous system function. Methods. Fractionation R. officinalis led to isolation salvigenin, rosmanol cirsimaritin, which were mouse models acute toxicity, antinociception (tail immersion hot plate tests), depression suspension forced swim tests) anxiety...
To identify the chemical constituents of leaf essential oil Forsythia koreana (F. koreana) and evaluate its effects on bacterial strains.The F. was extracted by using hydrodistillation process volatile components investigated with help gas chromatography coupled mass spectrometry. The antibacterial study carried out agar disc diffusion method, MIC, MBC viable count. mode action determined potassium ion flux, cellular material release scanning electron microscopy. antioxidant activity 2,...
The utilization of a sustainable and lightweight graphene aerogel (GA), synthesized from crude biomass, as cell growth promoter an adsorbent for the efficient removal histamine (HIS), food toxicant, real matrix has been explored. Due to self-supported three-dimensional nanoporous honeycomb-like structure framework high surface area, GA achieved 80.69 ± 0.89% HIS red wine (spiked with HIS) after just 60 min under both acidic (3.0) neutral (7.4) pH conditions. Furthermore, simple cleaning 50%...
Two heterocyclic compounds named 2,6-diaminopyrimidin-4-ylnaphthalene-2-sulfonate (A) and 2,6-diaminopyrimidin-4-yl4-methylbenzene sulfonate (B) were synthesized. The structures of molecules established by the X-ray crystallographic technique, which showed several noncovalent interactions as N···H···N, N···H···O, C–H···O bonding parallel offset stacking interaction. Hydrogen-bonding further explored Hirshfeld surface (HS) analysis. Nonlinear optical (NLO) natural bond orbital (NBO)...