A5002615485- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Glioma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Radiation Therapy and Dosimetry
- Management of metastatic bone disease
- Esophageal Cancer Research and Treatment
- Vascular Malformations Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Cardiac Arrhythmias and Treatments
- Digital Radiography and Breast Imaging
- Intracranial Aneurysms: Treatment and Complications
- Spinal Fractures and Fixation Techniques
- Growth Hormone and Insulin-like Growth Factors
- Advances in Oncology and Radiotherapy
- Radiation Effects and Dosimetry
- Neurological disorders and treatments
- Medical Imaging and Analysis
- Chemistry and Chemical Engineering
- Drilling and Well Engineering
University of Bern
2010-2024
University Hospital of Bern
2011-2024
Medical University of Vienna
2022
Software (Spain)
2022
Istanbul Yeni Yüzyıl University
2018
Royal London Hospital
2016
University College London
2016
Institute for Biomedical Engineering
2007
Purpose: The aim of this work is to evaluate the geometric accuracy a prerelease version new six degrees freedom (6DoF) couch. Additionally, quality assurance method for 6DoF couches proposed. Methods: main principle performance tests was request known shift couch and compare requested with actually applied by independently measuring using different methods (graph paper, laser, inclinometer, imaging system). each axes tested separately as well in combination other axes. Functional cases...
STereotactic Arrhythmia Radioablation (STAR) showed promising results in patients with refractory ventricular tachycardia. However, clinical data are scarce and heterogeneous. The STOPSTORM.eu consortium was established to investigate harmonize STAR Europe. primary goal of this benchmark study current treatment planning practice within the STOPSTORM project as a baseline for future harmonization.
The aim of this work is to investigate what extent it possible use the secondary collimator jaws reduce transmitted radiation through multileaf (MLC) during an intensity modulated therapy (IMRT). A method developed and introduced where follow open window MLC dynamically (dJAW method). With aid three academic cases (Closed MLC, Sliding‐gap, Chair) two clinical (prostate head neck) feasibility dJAW influence on applied dose distributions are investigated. For purpose treatment planning system...
Purpose: The aim of this work was a Monte Carlo (MC) based investigation the impact different radiation transport methods in collimators linear accelerator on photon beam characteristics, dose distributions, and efficiency. Thereby it is investigated if possible to use simplifications for some clinical situations order save calculation time. Methods: Within Swiss Plan, GUI‐based framework MC treatment planning, are available through [secondary jaws multileaf collimator (MLC)]: EGSnrc...
Dose, fractionation, normalization and the dose profile inside target volume vary substantially in pulmonary stereotactic body radiotherapy (SBRT) between different institutions SBRT technologies. Published planning studies have shown large variations of mean (PTV) gross tumor (GTV) or internal (ITV) when prescription is performed to PTV covering isodose. This study investigated whether ITV improves consistency distributions.This was a multi-institutional by German Society Radiation Oncology...
Monte Carlo (MC) based dose calculations can compute distributions with an accuracy surpassing that of conventional algorithms used in radiotherapy, especially regions tissue inhomogeneities and surface discontinuities. The Swiss Plan (SMCP) is a GUI-based framework for photon MC treatment planning (MCTP) interfaced to the Eclipse system (TPS). As any calculation algorithm, also MCTP needs be commissioned validated before using algorithm clinical cases. Aim this study investigation 6 MV beam...
Abstract Background and purpose To assess the feasibility of postoperative stereotactic body radiation therapy (SBRT) for patients with hybrid implants consisting carbon fiber reinforced polyetheretherketone titanium (CFP-T) using CyberKnife. Materials methods All essential steps within a (RT) workflow were evaluated. First, contouring process target volumes organs at risk (OAR) was done CFP-T implants. Second, after RT-planning, accuracy calculated dose distributions tested in slab phantom...
This work aims to develop, implement and validate a Monte Carlo (MC)-based independent dose calculation (IDC) framework perform patient-specific quality assurance (QA) for multi-leaf collimator (MLC)-based CyberKnife® (Accuray Inc., Sunnyvale, CA) treatment plans. The IDC uses an XML-format plan as exported from the planning system (TPS) DICOM format patient CT data, MC beam model using phase spaces, CyberKnife MLC modifier transport EGS++ class library, sampling coordinate transformation...
Vendor-independent Monte Carlo (MC) dose calculation (IDC) for patient-specific quality assurance of multi-leaf collimator (MLC) based CyberKnife treatments is used to benchmark and validate the commercial MC engine MLC built into treatment planning system (Precision MC).The included profiles in water 15 mm depth curves rectangular shaped fields ranging from 7.6 × 7.7 115.0 100.1 mm, which were compared between IDC, Precision measurements terms difference distance agreement. Dose...
Abstract Compared to a conventional linear accelerator, the Cyberknife ( CK ) is unique system with respect radiation protection shielding and variety number of non‐coplanar beams are two key components regarding this aspect. In work, framework assess direction distribution modulation factor MF clinically applied treatment CyberKnife M6 developed. Database filtering options allow studying influence different parameters such as collimator types, sites or bunker sizes. A monitor units MU...
Neo-adjuvant chemoradiotherapy (CRT) and perioperative chemotherapy are different strategies for treating non-metastatic esophageal cancer (EC). The advantages of neo-adjuvant therapies primarily seen in patients who achieve a pathologic complete response (pCR) therefore show higher survival rates better prognosis. In general, less than one-third with EC experience pCR after therapies; however, adenocarcinoma (AC) demonstrate lower compared to those squamous cell carcinoma (SCC),...
Radiation therapy (RT) plays a key role in the management of esophageal cancer (EC). However, toxicities caused by proximity organs at risk (OAR) and daily target coverage interfractional anatomic changes are concern. Daily online adaptive RT (oART) addresses these concerns has potential to increase OAR sparing improve coverage. We present first clinical experience dosimetric investigations cone beam CT-based oART EC using ETHOS platform.