- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Breast Lesions and Carcinomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Effects of Radiation Exposure
- Management of metastatic bone disease
- Glioma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Prostate Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Cancer Genomics and Diagnostics
- Prostate Cancer Treatment and Research
- Radiation Dose and Imaging
- Radiopharmaceutical Chemistry and Applications
- Gastric Cancer Management and Outcomes
- Advanced X-ray and CT Imaging
- Radiation Therapy and Dosimetry
- Breast Implant and Reconstruction
- Advances in Oncology and Radiotherapy
- Lung Cancer Research Studies
MSH Medical School Hamburg – University of Applied Sciences and Medical University
2022-2025
Helios Hospital Schwerin
2022-2025
Klinikum rechts der Isar
2015-2024
Technical University of Munich
2013-2024
Friedrich Schiller University Jena
2017-2023
University of KwaZulu-Natal
2023
Jena University Hospital
2019-2022
Klinik und Poliklinik für Strahlentherapie und Radioonkologie
2009-2021
Center for Clinical Studies
2021
Deutschen Konsortium für Translationale Krebsforschung
2018-2020
The intent of this pooled analysis as part the German society for radiation oncology (DEGRO) stereotactic body radiotherapy (SBRT) initiative was to analyze patterns care SBRT liver oligometastases and derive factors influencing treated metastases control overall survival in a large patient cohort. From 17 Swiss centers, data on all patients with since its introduction 1997 has been collected entered into centralized database. In addition tumor characteristics, immobilization, image guidance...
The aim of this analysis was to model the effect local control (LC) on overall survival (OS) in patients treated with stereotactic body radiotherapy (SBRT) for liver or lung metastases from colorectal cancer.The is based pooled data two retrospective SBRT databases pulmonary and hepatic 27 centers Germany Switzerland. Only cancer were considered avoid histology as a confounding factor. An illness-death employed relationship between LC OS.Three hundred eighty-eight 500 metastatic lesions...
The impact of local tumor ablative therapy in oligometastasized prostate cancer (PC) is still under debate. To gain data for this approach, we evaluated PC patients receiving stereotactic body radiotherapy (SBRT) to bone metastases.In retrospective study, 15 with a total 20 metastases were regarding biochemical progression-free survival (PSA-PFS), time initiation ADT, and control rate (LCR). Three received concomitant androgen deprivation (ADT).The median follow-up after RT was 22.5 months...
Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where can be actively released. Therefore, membrane soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers for monitoring the outcome of radiation therapy. Biopsies blood collected patients with squamous carcinoma head neck (SCCHN) at different time points (before, during therapy in follow-up period). expression was determined single suspensions...
PurposeTo investigate the influence of interfractional changes on delivered dose intensity modulated proton (IMPT) and photon plans (IMXT).Methods materialsFive postoperative head neck cancer patients, previously treated with tomotherapy at our institute, were analyzed. The planning study is based megavoltage (MV) control images. For each patient one IMPT plan IMXT generated first MV-CT recalculated weekly MV-CTs in actual treatment position. Dose criteria for evaluation coverage conformity...
Renal cell carcinoma (RCC) is traditionally considered to be radioresistant. Radiotherapy response rates are believed improve with hypofractionated, high dose stereotactic body radiotherapy (SBRT). However, limited data exist regarding the role of SBRT in treatment pulmonary metastases.The working group "Stereotactic Radiotherapy" German Society Radiation Oncology analyzed its multi-institutional database more than 700 patients who received for metastases. Treatment was performed at 10...
The aim of this review was to evaluate the existing evidence for radiotherapy brain metastases in breast cancer patients and provide recommendations use leptomeningeal carcinomatosis.
This study was performed to evaluate skin toxicity during modern three-dimensional conformal radiotherapy (3D-CRT) and the importance of dose distribution patient related factors.This comprises 255 patients with breast cancer treated tangential after conserving surgery between 03/2012 05/2017. The median prescribed 50.4 Gy (range 50-50.4) 92.2% received a sequential boost 10-16 Gy. Adverse toxicities (according CTCAE v. 4.03 occurrence moist desquamations) were assessed at end treatment. in...