A5101565048- Breast Cancer Treatment Studies
- Metastasis and carcinoma case studies
- Cancer Cells and Metastasis
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Atrial Fibrillation Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Diagnosis and treatment of tuberculosis
- Cancer Diagnosis and Treatment
- Inflammatory Bowel Disease
- Hemodynamic Monitoring and Therapy
- Fault Detection and Control Systems
- Gastrointestinal Tumor Research and Treatment
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Genetic factors in colorectal cancer
- Medical Imaging Techniques and Applications
- Colorectal and Anal Carcinomas
- Estrogen and related hormone effects
- Cancer Immunotherapy and Biomarkers
- Medical Research and Treatments
- Thyroid Disorders and Treatments
Xiangyang Central Hospital
2024
Zhongnan Hospital of Wuhan University
2013-2022
Wuhan University
2013-2022
Hubei Cancer Hospital
2016-2022
Shantou University
2020
Yue Bei People's Hospital
2020
Dalian Medical University
2017
First Affiliated Hospital of Dalian Medical University
2017
Cancer Clinic
2017
Dongguan People’s Hospital
2012
mRNA expression profiles provide important insights on a diversity of biological processes involved in rectal carcinoma (RC). Our aim was to comprehensively map complex interactions between the patterns and clinical traits RC. We employed integrated analysis five microarray datasets The Cancer Genome Atlas adenocarcinoma database identify 2118 consensual differentially expressed genes (DEGs) RC adjacent normal tissue samples, then applied weighted gene co-expression network parse DEGs eight...
Previous studies have demonstrated that the tumor-stromal ratio (TSR) was an independent prognostic factor in several types of carcinomas. This study aimed at exploring significance TSR invasive breast cancer using immunohistochemistry (IHC)-stained tissue microarrays (TMAs) and integrating into traditional tumor-node-metastasis (TNM) staging system. The prepared 7 TMAs containing 240 patients with 480 BC specimens were stained cytokeratin (CK) by IHC staining method. tumor cells stromal...
Background: Various studies have verified the prognostic significance of tumor-stromal ratio (TSR) in several types carcinomas using manually assessed H&E stained histologic sections.This study aimed to establish a computerized method assess TSR invasive breast cancer (BC) immunohistochemistry (IHC)-stained tissue microarrays (TMAs), and integrate into novel nomogram for predicting survival.Methods: IHC-staining cytokeratin (CK) was performed 7 prepared TMAs containing 240 patients with 480...
Abstract Although adjuvant chemoradiotherapy has been an important part in the treatment of gastric cancer, whether or not radiation can benefit patients undergoing resection with D2 lymph node dissection remains controversial. This retrospective study aimed to evaluate role on D2‐resected cancer. A total 337 resected cancer treated at Zhongnan Hospital Wuhan University from 2004 2012 were retrospectively analyzed. Eligible divided into group ( CRT ; n = 124) and chemotherapy CT 213). The...
Abstract Background: The ACTS-GC study had shown postoperative adjuvant therapy with S-1 improved survival of patients locally advanced gastric cancer. Addition oxaliplatin to is considered be acceptable as one the treatment options for cancer after radical gastrectomy D2 lymph node excision. Methods: We have commenced a randomized phase III trial in December 2016 evaluate plus compared alone setting A total 564 will accrued from 13 Chinese institutions two years. primary endpoint 3-year...
Trastuzumab has been demonstrated to be an effective treatment in patients with human epidermal growth factor receptor-2 (HER-2) positive breast cancer (BC); however, inconsistent results regards the long-term survival benefits, safety and optimal administration timing of trastuzumab exist. The present meta-analysis investigated these inconsistencies HER-2 BC that received adjuvant or neoadjuvant trastuzumab. Computerized manual searches were used identify eligible randomized control trials...
Abstract Background The tumor‐stromal ratio (TSR) has been verified to be a prognostic factor in many solid tumors. In most studies, it was manually assessed on routinely stained H&E slides. This study aimed assess the TSR using image analysis algorithms developed by Qupath software, and integrate into nomogram for prediction of survival invasive breast cancer (BC) patients. Methods A modified assessment algorithm based recognition tumor stroma tissues software. 234 BC specimens...
Objective Exploration of the Predictive Diagnostic Value Mean Platelet Volume to Count Ratio (MPV/PLT,PVI) and Neutrophil-to-Lymphocyte (NLR) in tPSA Gray Zone Prostate Cancer Methods A retrospective study was conducted on 65 prostate cancer (Pca) patients 52 benign prostatic hyperplasia (BPH) who underwent transperineal biopsy at Xiangtan Central Hospital from December 2021 2023. Descriptive statistics logistic regression models were used investigate predictive diagnostic value PVI NLR gray...
Abstract Background Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it’s not always available. So we aim establish a diagnostic scale for SAT without radioisotope scanning. Methods The suspected patients hospitalized in Yuebei people’s Hospital from January 2012 December 2016 were selected and divided into study group control according whether they diagnosed as SAT. clinical indexes of two groups collected the was established by using binary logistic regression...
Objective To find out the relationship between periferal blood neutrophil to lympnocyte ratio and various clinicopathological factors in patients with gastric cancer.Methods A total of 201 cancer,who underwent curative resection our hospital,were included.A 65 lymphocyte (NLR) 2.9 or more were classified as high NLR individuals,while other was under this study.Various including depth invasion,pathological histological characteristics,lymph node metastasis tumor recurrence analyzed...