A5029994638- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Viral-associated cancers and disorders
- RNA modifications and cancer
- MicroRNA in disease regulation
- Lymphoma Diagnosis and Treatment
- FinTech, Crowdfunding, Digital Finance
- RNA Research and Splicing
- Cancer-related molecular mechanisms research
- Metabolomics and Mass Spectrometry Studies
- Sharing Economy and Platforms
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Identification and Quantification in Food
- Chronic Kidney Disease and Diabetes
- Job Satisfaction and Organizational Behavior
- Genomics and Chromatin Dynamics
- Transportation and Mobility Innovations
- Liver Disease Diagnosis and Treatment
- Computational Drug Discovery Methods
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cholinesterase and Neurodegenerative Diseases
First Affiliated Hospital of GuangXi Medical University
2024
Guangxi Medical University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Xiyuan Hospital
2024
Hangzhou Red Cross Hospital
2024
Guangzhou University of Chinese Medicine
2024
Northwest University
2016-2023
University of Alabama
2020-2023
Wuhan University
2022
Hubei Cancer Hospital
2022
Generative AI tools such as ChatGPT have recently gained significant attention in higher education. This study aims to understand how universities establish policies regarding the use of and explore factors that influence their decisions. Our examines implemented at around world, including existence, content (i.e., whether they embrace or ban coverage) issuance dates. Specifically, we analyzed top 500 according 2022 Quacquarelli Symonds (QS) World University Rankings. findings indicate there...
DNA methylation 5-methylcytosine (5mC) predicts a compacting chromatin inaccessible to transcription. The discovery of 5-hydroxymethylcytosine (5hmC), which is derived from 5mC, adds new dimension the mechanism and role in epigenetics. Genomic evidence indicates that 5hmC located alternate regions 5mC. However, nature 5hmC, as compared with classical 5mC remains unclear. Observing mouse brain through embryonic development adult, first, we found not merely an intermediate metabolite...
Increasing evidence has indicated that the high risk of cardiovascular disease in chronic kidney (CKD) patients cannot be sufficiently explained by classic factors.Based on least absolute shrinkage and selection operator method, we identified significantly altered renal tissue metabolites during progressive CKD a 5/6 nephrectomized rat model patients.Six aryl-containing (ACMs) were increased from Week 1 to 20. They associated with activation aryl hydrocarbon receptor (AhR) its target genes...
Sinonasal non-Hodgkin's lymphomas (SNHL) of B- or T-cell immunophenotype have been associated with the Epstein-Barr virus (EBV) in Asian patients. We investigated eight sinonasal and 10 Waldeyer's ring NHL from Western patients for evidence EBV genomes using a sensitive situ hybridization technique. DNA was detected each three two five cases B-cell immunophenotype. Two were positive genomes. In case, evenly distributed among neoplastic cells, whereas no nonneoplastic lymphocytes epithelium...
Increasing evidence suggests a link between the gut microbiome and various diseases including hypertension chronic kidney disease (CKD). However, studies examining efficacy of controlling blood pressure inhibiting renin-angiotensin system (RAS) in preventing CKD progression are limited.In present study, we used 5/6 nephrectomised (NX) unilateral ureteral obstructed (UUO) rat models cultured renal tubular epithelial cells fibroblasts to test whether alisol B 23-acetate (ABA) can attenuate...
Abstract Compounds 1 a and b were prepared by appending two tetrathiafulvalene (TTF) units to an aromatic amide segment that is driven six or intramolecular NH⋅⋅⋅O hydrogen bonds adopt folded conformation. UV/Vis absorption experiments revealed if the TTF oxidized .+ radical cations, compounds could form stable single molecular noncovalent macrocycle in less polar dichloromethane dichloroethane bimolecular binary mixture of with more solvent owing remarkably enhanced dimerization units. The...
Genome-wide association studies have identified the susceptibility single nucleotide polymorphisms (SNPs) of glioma at chromosome 20q13.33, and replication study conducted among Chinese Han population also confirmed locus rs6010620 is located in this region. To identify other genetic variants we genotyped 13 common tagging SNPs imputed 86 additional a region ∼100 kb 20q13.33 1027 controls 987 cases. Among 99 SNPs, five independent loci (20-62315594 RTEL1 , 20-62335293 adenosine diphosphate...
The aim of the present study was to explore changes in urinary metabolic spectrum rats with knee osteoarthritis, using gas chromatography-time flight/mass spectrometry (GC-TOF/MS) determine metabonomic disease pathogenesis. Sprague-Dawley were randomly divided into control and model groups (n=8/group), 20 µl 4% papain 0.03 M L-cysteine injected right on days 1, 3 7 establish osteoarthritis model. Following 14 days, urine collected over 12 h cartilage ultrastructural damage assessed by...
Glioma is the most common malignant primary brain tumors with poor prognosis. Genome wide association studies (GWAS) of glioma in populations Western European ancestry were completed US and UK. However, our previous results strongly suggest genetic heterogeneity could be important risk. To systematically investigate risk-associated variants Chinese population, we performed a multistage GWAS Han total 3,097 cases 4,362 controls. In addition to confirming two associations reported other...
Aims Isoniazid (INH) has been used as a first‐line drug to treat tuberculosis (TB) for more than 50 years. However, large interindividual variability was found in its pharmacokinetics, and effects of nonadherence INH treatment corresponding remedy regime remain unclear. This study aimed develop population pharmacokinetic (PPK) model Chinese patients with TB provide model‐informed precision dosing explore appropriate remedial regimens nonadherent patients. Methods In total, 1012 observations...
This study aimed to develop postsurgical progression/hyperprogression recurrence (type III-IV recurrence) prediction models for hepatocellular carcinoma (HCC) patients with macroscopic vascular invasion (MaVI) and guide treatment strategies in the accurate healthcare era. 393 HCC MaVI from two central hospitals made up entire population. In developmental (290 patients) validation (103 cohorts, all were randomized into one or other. Two type developed, based on findings of univariate...