Xingye Zhang

ORCID: 0000-0002-0016-4676
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About
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Research Areas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Traumatic Brain Injury Research
  • Circular RNAs in diseases
  • Cerebrospinal fluid and hydrocephalus
  • S100 Proteins and Annexins
  • Acute Ischemic Stroke Management
  • Cancer-related molecular mechanisms research
  • Anesthesia and Neurotoxicity Research
  • Neurological Disorders and Treatments
  • Surgical site infection prevention
  • Medicinal Plants and Bioactive Compounds
  • Nanoparticles: synthesis and applications
  • RNA Research and Splicing
  • Intracranial Aneurysms: Treatment and Complications
  • Heme Oxygenase-1 and Carbon Monoxide
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Trauma and Emergency Care Studies
  • Head and Neck Surgical Oncology
  • Neuroblastoma Research and Treatments
  • Neurological Disease Mechanisms and Treatments
  • Surgical Sutures and Adhesives
  • Wound Healing and Treatments
  • Meningioma and schwannoma management

Air Force Medical University
2013-2024

Tang Du Hospital
2023-2024

Moderate traumatic brain injury (mTBI) is a heterogeneous entity that poorly defined in the literature. Patients with mTBI have high rate of neurological deterioration (ND), which usually accompanied by poor prognosis and no definitive methods to predict. The purpose this study develop validate prediction model estimates ND risk patients using data collected on admission. Data for 479 retrospectively our department were analyzed logistic regression models. Bivariable identified variables p <...

10.1089/neu.2021.0360 article EN Journal of Neurotrauma 2022-01-12

Spontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke, which leads to high rate mortality and poor neurological outcomes worldwide. Thrombolytic evacuation with urokinase-type plasminogen activator (uPA) or tissue-type (tPA) has been showed be hopeful treatment for ICH. However, the best our knowledge, no clinical trials were reported compare efficacy safety these two fibrinolytics administrated following minimally invasive stereotactic puncture (MISP) in patients...

10.3389/fneur.2017.00371 article EN cc-by Frontiers in Neurology 2017-08-02

// Yuqian Li 1, * , Gang Zhu Wen Zeng Jiancai Wang 1 Zhihong Bao Bo Tian Dan Lu Xingye Zhang Guodong Gao and Lihong Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, 710038, China These authors contributed equally to this work Correspondence to: Li, email: 617336343@qq.com Gao, 332568488@qq.com Keywords: AB073614, glioma, long noncoding RNA, SOX7, Wnt/β-catenin Received: April 03, 2017 Accepted: June 28, Published: July 17, ABSTRACT Long RNA...

10.18632/oncotarget.19305 article EN Oncotarget 2017-07-17

Single-wall carbon nanohorns (SWNHs) have been demonstrated to accumulate in cytotoxic levels within organs of various animal models and cell types, which emerge as a wide range promising biomedical imaging. Septic encephalopathy (SE) is an early sign sepsis associated with increased rate morbidity mortality. Microglia activation plays important role neuroinflammation, contributes neuronal damage. Inhibition microglia may therapeutic benefits, can alleviate the progression neurodegeneration....

10.1186/1556-276x-8-100 article EN cc-by Discover Nano 2013-02-22

Glioma is one of the most common and aggressive malignant intracranial tumors worldwide. Recently, non‑coding RNAs have been found to play critical roles in development glioma. However, exact mechanisms not fully elucidated. In present study, reverse transcription‑quantitative PCR was used determine expression level long RNA MIR22HG microRNA (miR)‑9, while western blot analysis detect protein CPEB3. The potential binding sites were predicted using StarBase v2.0 online tool hypothesis...

10.3892/ol.2020.12418 article EN Oncology Letters 2020-12-31

Wnt/β-catenin signaling is engaged in various biological processes, including the development of central nervous system. The dysfunction mitochondrial has been shown to participate progress Subarachnoid hemorrhage(SAH). Traumatic subarachnoid hemorrhage(tSAH) a serious complications acute craniocerebral trauma. Opioids can activate canonical signaling. c-Myc, down-stream protein signaling, contribute fusion mitochondria. Here, we investigated protective roles Propoxyphene(Pro) against...

10.3389/fphar.2019.01616 article EN cc-by Frontiers in Pharmacology 2020-01-30

Objective To analyze the therapeutic effect of different methods on subdural effusion after decompressive craniectomy (DC) in patients with severe traumatic brain injury (sTBI). Methods Fifty-six (38 males and 18 females) who developed following DC from January 2013 to 2015 were reviewed retrospectively. Age was (36.1±13.5)years (range, 12-76 years). Brain traffic accident 42 patients, high fall 7, trauma 4 hit by heavy objects 3. There 8 accelerated injury, 45 decelerated 3 crush...

10.3760/cma.j.issn.1001-8050.2016.07.007 article EN Zhonghua chuangshang zazhi 2016-07-15

Abstract Objective: patients with moderate traumatic brain injury (TBI) are under the threat of intracranial hypertension(IHT), which is an important cause death and unfavorable outcome TBI patients. However, it unclear will develop IHT when to receive ICP-lowering treatment or even invasive ICP monitoring after admission. The purpose present study was validate a prediction model that estimates risk in lower GCS (9-11) by admission data. Methods : baseline data collected on 296 score 9-11...

10.21203/rs.3.rs-2909472/v1 preprint EN cc-by Research Square (Research Square) 2023-05-17
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