Adil Muhammad
A5047363768- Neonatal and Maternal Infections
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Advanced Drug Delivery Systems
- Agroforestry and silvopastoral systems
- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Enterobacteriaceae and Cronobacter Research
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Global Maternal and Child Health
- Probiotics and Fermented Foods
- Pharmacological Effects of Natural Compounds
- Advancements in Transdermal Drug Delivery
- Antibiotics Pharmacokinetics and Efficacy
- Urinary Tract Infections Management
Quaid-i-Azam University
2021-2024
University of Edinburgh
2024
Pakistan Institute of Medical Sciences
2023
Cardiff University
2023
Federal University of Agriculture
2022
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of that often spread between species via mobile genetic elements, ultimately limiting treatments low- and middle-income countries (LMICs), are poorly characterized. The Burden Antibiotic Resistance Neonates from Developing Societies (BARNARDS) network was initiated to characterize the cause burden antimicrobial for seven LMICs Africa South Asia. A total 36,285 neonates were enrolled BARNARDS study November 2015 December...
BackgroundNeonatal sepsis is a primary cause of neonatal mortality and an urgent global health concern, especially within low-income middle-income countries (LMICs), where 99% occurs. The aims this study were to determine the incidence associations with all-cause in facility-born neonates LMICs.MethodsThe Burden Antibiotic Resistance Neonates from Developing Societies (BARNARDS) recruited mothers their into prospective observational cohort across 12 clinical sites Bangladesh, Ethiopia,...
Abstract Hospital surfaces can harbour bacterial pathogens, which may disseminate and cause nosocomial infections, contributing towards mortality in low- middle-income countries (LMICs). During the BARNARDS study, hospital from neonatal wards were sampled to assess degree of environmental surface patient care equipment colonisation by Gram-negative bacteria (GNB) carrying antibiotic resistance genes (ARGs). Here, we perform PCR screening for extended-spectrum β-lactamases ( bla CTX-M-15 )...
Abstract Early development of the microbiome has been shown to affect general health and physical infant and, although some studies have undertaken in high-income countries, there are few from low- middle-income countries. As part BARNARDS study, we examined rectal microbiota 2,931 neonates (term used up 60 d) with clinical signs sepsis 15,217 mothers screening for bla CTX-M-15 , NDM KPC OXA-48 -like genes, which were detected 56.1%, 18.5%, 0% 4.1% neonates’ swabs 47.1%, 4.6%, 1.6% mothers’...
In low- and middle-income countries (LMIC) Staphylococcus aureus is regarded as one of the leading bacterial causes neonatal sepsis, however there limited knowledge on species diversity antimicrobial resistance caused by Gram-positive bacteria (GPB).We characterised GPB isolates from blood cultures LMICs in Africa (Ethiopia, Nigeria, Rwanda, South Africa) South-Asia (Bangladesh Pakistan) between 2015-2017. We determined minimum inhibitory concentrations performed whole genome sequencing...
Abstract Inanimate surfaces in hospital settings can harbour bacterial pathogens, which disseminate and cause nosocomial infections, resulting unacceptable mortality low- middle-income countries (LMICs). As part of the BARNARDS study, this swabs study determined were colonised by Gram-negative bacteria (GNB) carrying antibiotic resistance genes (ARGs). PCR screening for presence extended-spectrum β-lactamases ( bla CTX-M-15 ) carbapenemases NDM , OXA-48 -like KPC showed higher prevalence...