- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Cardiac tumors and thrombi
- Urologic and reproductive health conditions
- Histiocytic Disorders and Treatments
- Cervical Cancer and HPV Research
- Soft tissue tumors and treatment
- Neuroendocrine Tumor Research Advances
- Vascular Malformations and Hemangiomas
- Gastrointestinal Tumor Research and Treatment
- Bone Tumor Diagnosis and Treatments
- Medical Imaging and Pathology Studies
- Musculoskeletal synovial abnormalities and treatments
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Cancer Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Neurofibromatosis and Schwannoma Cases
- Breast Lesions and Carcinomas
- Oral and Maxillofacial Pathology
- Lymphoma Diagnosis and Treatment
- Ear and Head Tumors
- Case Reports on Hematomas
University of Michigan
2024-2025
Missouri University of Science and Technology
2024
Henry Ford Health System
2018-2023
Henry Ford Hospital
2018-2023
Yale University
2022
University of California, San Diego
2022
Mayo Clinic in Arizona
2017-2021
Baylor College of Medicine
2021
University of Mississippi Medical Center
2021
University of Miami
2021
Diffuse large B-cell lymphoma (DLBCL) includes at least two prognostically important subtypes (ie, germinal center B-cell-like [GCB] and activated [ABC] DLBCL), which initially were characterized by gene expression profiling subsequently confirmed immunostaining. However, with the addition of rituximab to standard chemotherapy, prognostic significance this subclassification DLBCL is unclear.We studied 243 patient cases de novo DLBCL, included 131 treated plus chemotherapy (rituximab group)...
Aberrant expression of neuroendocrine markers is extremely rare in endothelial neoplasms, with only a single report describing three cases. Although originally classified as conventional angiosarcoma, further assessment these tumors revealed strikingly composite morphology composed retiform and epithelioid elements reminiscent hemangioendothelioma, subtype hemangioendothelioma. To investigate findings, available materials from 11 morphologically distinctive showing marker were retrieved our...
Liposarcoma (LPS) is the most prevalent soft tissue sarcoma. The common biological subtypes are well-differentiated (WDLPS), a low-grade disease that can evolve to high-grade dedifferentiated LPS (DDLPS), with increased rates of recurrence and metastasis low response chemotherapy targeted therapies. Preclinical testing immunotherapeutics for has been held back by lack an immunocompetent mouse model. Here, we present spontaneous model, ACPP, deletion Trp53 Pten in adipocytes mimic signaling...
Perry K D, Reynolds C, Rosen D G, Edgerton M E, Albarracin C T, Gilcrease Z, Sahin A A, Abraham S & Wu Y(2011) Histopathology59, 619–630 Metastatic neuroendocrine tumour in the breast: a potential mimic of in-situ and invasive mammary carcinoma Aims: The aim this study was to review clinicopathological characteristics tumours (NETs) metastasizing breast, order identify features that could be useful distinguishing these metastatic lesions from primary breast neoplasms. Methods results:...
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has emerged as the diagnostic modality of choice for mass lesions in pancreas. The objective current study was to determine accuracy and pitfalls EUS-FNA diagnosis pancreatic cases that involved follow-up surgical resection.Cases performed from 2007 mid-2012 which subsequent resection were retrieved department's database. cytologic assessed using histological gold standard. sensitivity, specificity, positive predictive value,...
Pseudosarcomatous myofibroblastic proliferations of the genitourinary tract have a debatable relationship with inflammatory tumour (generally lacking ALK rearrangement); however, they share several overlapping features nodular fasciitis soft tissue. As rearrangement USP6 gene has been recently recognised as recurrent alteration in tissue fasciitis, and other alternative fusions tumour, aim this study was to investigate whether USP6, ROS1 or ETV6 rearrangements were present these lesions (12...
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) and spindle cell lipoma are tumors with distinct clinical, molecular, prognostic features. Although histological immunophenotypic features can overlap between ALT/WDL lipoma, the oncogenesis clinical behavior markedly different. In borderline cases, molecular analysis for MDM2 or CDK4 amplification aid in distinguishing from lipoma. dedifferentiated has been reported to harbor both loss of RB1 region, we not aware a...
To determine whether the pre-medical Grade Point Average (GPA), Medical College Admission Test (MCAT), Internal examinations (Block) and National Board of Examiners (NBME) scores are correlated with predict Council Canada Qualifying Examination Part I (MCCQE-1) scores.Data from 392 admitted students in graduating classes 2010-2013 at University Manitoba (UofM), Medicine was considered. Pearson's correlation to assess strength relationship, multiple linear regression estimate MCCQE-1 score...
Dyshormonogenetic goiter is a rare entity that presents in patients who typically have history of congenital hypothyroidism, and generally arises from genetic mutation compromising the production functional thyroxine or thyroglobulin. Clinically, physical manifestations can result if left untreated. Histologically, thyroid lesions usually show prominent bridging fibrosis, multiple nodules with different architectures, microfollicular arrangement, scant colloid, enlarged vesicular...
Abstract Background Nuclear protein in testis (NUT) carcinoma (NC) is an aggressive type of poorly differentiated with a variable degree squamous differentiation. NC defined by the presence BRD‐NUT fusion oncogenes, most common form being BRD4‐NUTM1 gene. Variant rearrangements involving BRD3 and NSD3 genes. genes occur approximately one‐third cases. Aims This first case regarding study cytological features lung BRD3‐NUTM1 fusion. Materials Methods A 36‐year‐old female chest heaviness...
8040 Background: Diffuse large B-cell lymphoma (DLBCL) includes at least two prognostically important subgroups, i.e. germinal center (GCB) and activated (ABC) DLBCL, which were initially characterized by gene expression profiling subsequently validated immunostaining. Bcl-2 has also been identified as a prognostic indicator in the ABC subgroup. However, with addition of rituximab (R) to standard chemotherapy, significance this subclassification DLBCL is unclear. Methods: We studied 119...
Immunohistochemical staining can be of great utility in differentiating various cutaneous spindle cell neoplasms, particularly when the histomorphologic appearance lesions is inconclusive. Nuclear for ETS-related gene (ERG), a highly sensitive endothelial marker, has seldom been studied context neoplasms. Little known about its specificity vascular differentiation. In this pilot study, immunohistochemical analysis ERG was performed on 15 dermatofibromas (DF), 10 keloids, and 9...