A5013420781- Rheumatoid Arthritis Research and Therapies
- Cancer-related molecular mechanisms research
- Gout, Hyperuricemia, Uric Acid
- Pharmacological Effects of Natural Compounds
- Osteoarthritis Treatment and Mechanisms
- Spondyloarthritis Studies and Treatments
- Inflammatory mediators and NSAID effects
- Inflammatory Biomarkers in Disease Prognosis
- Autoimmune and Inflammatory Disorders Research
- Network Security and Intrusion Detection
- Internet Traffic Analysis and Secure E-voting
- Mycobacterium research and diagnosis
- Cytokine Signaling Pathways and Interactions
- Traditional Chinese Medicine Studies
- Inflammasome and immune disorders
- Anomaly Detection Techniques and Applications
- Geotechnical Engineering and Underground Structures
- Connective Tissue Growth Factor Research
- Grouting, Rheology, and Soil Mechanics
- Erythrocyte Function and Pathophysiology
- Macrophage Migration Inhibitory Factor
- Lipid metabolism and disorders
- Railway Engineering and Dynamics
- Fatty Acid Research and Health
- Blood properties and coagulation
Anhui University of Traditional Chinese Medicine
2021-2025
Qilu University of Technology
2023
Shandong Academy of Sciences
2023
China Academy of Railway Sciences
2022
Beijing Jiaotong University
2018
Xinfeng capsule is a traditional Chinese medicine compound, which has been clinically used for more than 20 years in the treatment of rheumatoid arthritis (RA), ankylosing spondylitis, osteoarthritis and its extracurricular lesions. However, molecular role XFC RA remains unclear.This study aims to explore efficacy potential mechanism through retrospective data mining analysis, animal experiments cell experiments.The effect on clinical laboratory indexes patients was observed using techniques...
Gouty arthritis (GA) is a characteristically inflammatory disease often associated with lipid metabolism disorder. Huangqin Qingrechubi capsule (HQC) has been used for the treatment of GA.To explore mechanism HQC in GA.A total 30 GA patients (GA group) and healthy subjects [normal control (NC) group] were recruited. The group was treated (3.6 g/d) 10 days. Lipid inflammation indexes detected. Five herbal names HQC, or 'gouty arthritis', 'hyperlipidemia' 'inflammation' as key words to search...
Abstract Objective This study aims to investigate the correlation of long non-coding RNA HOX transcript antisense (lncRNA HOTAIR) with PTEN/PI3K/AKT pathway and clinical-related indicators in osteoarthritis (OA) determine effect baicalin intervention. Methods The levels clinical lipid metabolism indexes immune-inflammatory OA patients normal controls was detected. chondrocytes (OA-CHs) were induced peripheral blood mononuclear cells (PBMCs), followed by treatment (50 ug/mL). RT-qPCR...
Abstract Background Abnormal expression of long noncoding RNAs (lncRNAs) is involved in several autoimmune diseases including rheumatoid arthritis (RA). In this study, we intended to explore the lncRNA LINC00638 RA and its potential mechanism action related inflammation oxidative stress. Methods The level peripheral blood mononuclear cells (PBMCs) obtained from 45 patients 30 normal controls was analyzed correlation with clinical indicators investigated. vitro, used tumor necrosis factor‐α...
This study examined the relationship of Sharp score with demographic factors and clinical immune-inflammatory markers in patients anemia rheumatoid arthritis (RA).The data 1057 RA 1006 without were retrospectively analyzed. Spearman's correlation coefficient analysis, association rule logistic regression used to relationships between influencing anemia.The incidence was 51.24% (1057/2063), mild accounted for 81.93% (866/1057) cases. analyses revealed that correlated response anemia. Logistic...
Traditional Chinese medicine (TCM) has certain curative effect against acute gouty arthritis (AGA), but it lacks high-quality evidence-based studies. In this randomized controlled trial, we try to evaluate the clinical efficacy and safety of Qinpi Tongfeng Formula (QPTFF) in treatment AGA.One hundred fourteen patients with AGA (damp heat accumulation syndrome) who met inclusion exclusion criteria were randomly divided into group control a ratio 1 : 1. Patients treated QPTFF, diclofenac...
Abstract The rapid advancement of the Internet has brought a exponential growth in network traffic. At present, devices deployed at edge nodes process huge amount data, extract key features traffic and then forward them to cloud server/data center. However, since efficiency mobile terminal identifying classifying encrypted malicious lags behind, how identify more efficiently accurately remains challenging problem. We design convolutional neural model: One-dimensional with hexadecimal data...
Objective. This study aimed to analyze the effect of traditional Chinese medicine (TCM) on risk readmission for rheumatoid arthritis (RA) patients with anemia. Methods. In this study, 893 hospitalized RA were followed up by telephone. A retrospective cohort was conducted using propensity score matching (PSM). The Cox proportional hazards model used assess influence various factors Kaplan–Meier survival curve utilized TCM intervention time readmission. Results. incidence anemia 58.08%...
To evaluate whether traditional Chinese medicine compound preparations (TCMCPs) are associated with rheumatoid arthritis- (RA-) related complications (including readmission, Sjogren's syndrome, surgical treatment, and all-cause death) in patients RA.Clinical outcome data were retrospectively collected from RA discharged the Department of Rheumatology Immunology First Affiliated Hospital Anhui University Medicine January 2009 to June 2021. The propensity score matching method was used match...
Abstract The rapid development of the internet has brought a significant increase in network traffic, but efficiency categorizing different types traffic lagged behind, which downgraded cyber security. How to identify dimensions data with more and accuracy remains challenging issue. We design convolutional neural model HexCNN-1D that combines normalized processing attention mechanisms. By adding mechanism modules Global Attention Block (GAB) Category (CAB), were introduced classify recognize...
This study aimed to explore the correlation between traditional Chinese medicine(TCM) and reduced risk of readmission in patients having rheumatoid arthritis with hypoproteinemia(RA-H). A retrospective cohort was conducted on 2 437 information system database First Affiliated Hospital Anhui University Medicine from 2014 2021, 476 them were found have hypoproteinemia. The divided into TCM users non-TCM by propensity score matching. Exposure defined as use oral patent medicine or herbal...
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and joint destruction. Both inflammatory response oxidative stress contribute to the pathogenesis of RA. Oxidative damage can induce aggravate imbalance immune promote cell tissue damage. In this study, expression long non-coding RNA (lncRNA) LINC00638 in peripheral blood patients with RA damp-heat arthralgia syndrome was observed, correlation between activity, indicator investigated. Subsequently,...
There is a growing trend of applying traditional Chinese medicine (TCM) to treat immune diseases. This study reveals the possible mechanism luteolin, an active ingredient in core prescription TCM, alleviating systemic sclerosis (SSc) inflammation. Bibliometrics was performed retrieve keywords SSc The key inflammatory indicators serum samples 50 patients were detected by ELISA. Data mining applied for correlation analysis, association rule and binary logistic regression analysis on clinical...
Jianpi Qingre Tongluo Recipe (JQP) has been widely used in clinical practice, and its anti-Osteoarthritis (OA) effectiveness specific mechanism have concerned. This study aims to explore the effect of JQP reducing inflammation dyslipidemia OA molecular mechanism.
The narrow juncture defect makes continuous-slab-track become an eccentrically compressed structure. That may lead to interface crack between slab and CA mortar, affect the running security of vehicle in severe cases. multilayer structure characteristics CRTSII track were introduced firstly, propagation analysis model was established base on finite element method fracture mechanics. Stress intensity factor width calculated under different increasing extent temperature height juncture. Based...