A5038328550- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Gut microbiota and health
- Regulation of Appetite and Obesity
- Delphi Technique in Research
- Neonatal Respiratory Health Research
- Respiratory and Cough-Related Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inhalation and Respiratory Drug Delivery
- Antifungal resistance and susceptibility
- Congenital Diaphragmatic Hernia Studies
- Allergic Rhinitis and Sensitization
- Immune cells in cancer
- Fatty Acid Research and Health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Dietary Effects on Health
- Pneumonia and Respiratory Infections
- Pediatric health and respiratory diseases
- Respiratory viral infections research
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- IL-33, ST2, and ILC Pathways
University of Lausanne
2017-2024
University Hospital of Lausanne
2017-2023
University of Vermont
2012-2018
American Thoracic Society
2017
Maastricht University Medical Centre
2013-2016
University Medical Center
2012-2016
Maastricht University
2012-2016
Pulmonary Associates
2016
Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function linked with enhanced allergen sensitization and development diseases such as atopic dermatitis (AD), which can precede other allergic disorders, for example, food allergies asthma. Epidemiological evidence indicates that children suffering from have lower levels dietary fibre-derived short-chain fatty acids (SCFA). Using an experimental model AD-like inflammation, we report a...
Early-life microbial colonization of the skin may modulate immune system and impact development atopic dermatitis (AD) allergic diseases later in life. To address this question, we assessed association between microbiome AD, barrier integrity first year We further explored evolution with age its possible determinants, including delivery mode.
Section:ChooseTop of pageAbstract <<Materials and MethodsResultsDiscussionReferencesCITING ARTICLES
We have previously reported that obesity attenuates pulmonary inflammation in both patients with acute respiratory distress syndrome (ARDS) and mouse models of the disease. hypothesized obesity-associated hyperleptinemia, not body mass per se, drives attenuation inflammatory response this e_ect could also impair host to pneumonia. examined correlation between circulating leptin levels risk, severity, outcome pneumonia 2 patient cohorts (NHANES III ARDSNet-ALVEOLI) diet-induced lean...
Section:ChooseTop of pageAbstract <<ContentsMethodsObesity and Airway Diseas...Mitochondrial Cellula...Lipid Handling Mishan...ConclusionsReferencesCITING ARTICLES
Incomplete degradation of oxalate, a compound commonly found in the diet, can cause disease humans, particularly kidney. Its concentration body depends on several factors, one which is intestinal absorption, itself affected by oxalotrophy among enteric bacteria. Oxalotrophy human microbiome poorly known. In this study, we perform systematic search for simultaneous presence three genes, namely frc, oxc and oxlT. Thanks to construction validation specific conservation models all were able...
Aspergillus fungi are opportunistic pathogens that affect millions of people worldwide. Aspergilli produce organic acids to optimize the environmental pH and match needs their enzymatic machinery. In this study, we tested hypothesis also occurs during infection. By producing oxalic acid (OA), would manipulate lung infection thus, interfering with process could control pathogen. To test hypothesis, assessed in silico potential for OA production a wide range Aspergilli. A genetic marker AO was...
One of the hallmarks severe pneumonia and associated acute lung injury is neutrophil recruitment to lung. Leptin thought be up-regulated in following exert diverse effects on leukocytes, influencing both chemotaxis survival. We hypothesized that pulmonary leptin contributes directly development neutrophilia during injury.Controlled human murine vivo ex experimental studies.Research laboratory a university hospital.Healthy volunteers subjects hospitalized with bacterial H1N1 pneumonia....
Acute respiratory distress syndrome (ARDS) is characterized by an excessive pulmonary inflammatory response. Removal of excess cholesterol from the plasma membrane cells helps reduce their activation. The secreted apolipoprotein A-I binding protein (AIBP) has been shown to augment efflux endothelial lipoprotein HDL. Here, we find that AIBP was expressed in human lung and into bronchoalveolar space mice subjected inhalation LPS. bound surfactant B increased alveolar macrophages calfactant, a...
Section:ChooseTop of pageAbstract <<Materials and MethodsResultsDiscussionReferencesCITING ARTICLES
This article provides testimonials of the past and current chairs co-chairs ECMC (@EarlyCareerERS) a glimpse NEXT programme, along with participants' experiences. https://bit.ly/3LzvqKf.