A5100701692- Circular RNAs in diseases
- MicroRNA in disease regulation
- Polysaccharides and Plant Cell Walls
- Cancer-related molecular mechanisms research
- Selenium in Biological Systems
- Fibroblast Growth Factor Research
- Nuclear Receptors and Signaling
- Microbial Metabolites in Food Biotechnology
- Gut microbiota and health
- Fungal Biology and Applications
- Polyamine Metabolism and Applications
- Agriculture, Soil, Plant Science
- Analytical Chemistry and Chromatography
- Adipose Tissue and Metabolism
- Phytoestrogen effects and research
- Antimicrobial Peptides and Activities
- Curcumin's Biomedical Applications
- Laser-Ablation Synthesis of Nanoparticles
- Nitric Oxide and Endothelin Effects
- Ginseng Biological Effects and Applications
- Carbon and Quantum Dots Applications
- Mitochondrial Function and Pathology
- Amoebic Infections and Treatments
- Nanocomposite Films for Food Packaging
- Proteoglycans and glycosaminoglycans research
Southern Medical University
2024
Shandong Agricultural University
2019-2024
Zhujiang Hospital
2024
Heinrich Heine University Düsseldorf
2024
Southwest University
2024
Wuhan University of Science and Technology
2023-2024
Jinan University
2018-2023
Tiangong University
2023
Northeast Agricultural University
2023
Affiliated Hospital of Qingdao University
2021
Shandong indigenous pig breeds are an invaluable source of data on genetics in Chinese pigs. However, information the genetic basis these remains limited. In this study, we used specific-locus amplified fragment sequencing to conduct whole-genome screening investigate diversity and Western breeds. The results showed that Duroc pigs (DD) had clear relationships with Dapulian (DPL; Fst = 0.4386) Laiwu (LW; 0.5134), DPL LW were relatively close genetically (Fst 0.2334). general, greater variety...
Largemouth bass virus (LMBV) always causes a high mortality rate and results in severe economic losses among cultivated largemouth bass. However, the pathogenic mechanism of LMBV is still unclear there no specific antiviral treatment so far. The present study isolated identified highly strain from diseased challenge experiments revealed that infected juvenile fish suffered histopathological changes multiple tissues. Moreover, typical traits family Iridoviridae apoptosis signals were observed...
Abstract Background Globally, millions of patients suffer from regenerative deficiencies, such as refractory wound healing, which is characterized by excessive inflammation and abnormal angiogenesis. Growth factors stem cells are currently employed to accelerate tissue repair regeneration; however, they complex costly. Thus, the exploration new regeneration accelerators considerable medical interest. This study developed a plain nanoparticle that accelerates with involvement angiogenesis...
Selenium (Se) is an essential trace element involved in nearly all human physiological processes but suffers from a narrow margin between benefit and toxicity. The nanoform of selenium has been proven shown to be more bioavailable less toxic, yet significant challenges remain regarding the efficient feasible synthesis biologically active nanoselenium. In addition, although nanoselenium variety biological activities, interesting features are expected. this work, hydrosoluble termed Nano-Se...
Background We reported previously that Brown Norway ( BN ) rats are more resistant to myocardial ischemia/reperfusion (I/R) injury than Dahl S SS rats. To identify the unique genes differentially expressed in hearts of these rats, we used DNA microarray analysis and observed enoyl coenzyme A hydratase–containing domain 2 ECHDC 2) is highly (≈18‐fold) compared with hearts. Methods Results RT ‐ PCR , W estern blot, immunohistochemistry analyses verified was gene locates at chromosome 5 rat...
In eukaryotes, autophagy is induced as an innate defense mechanism against pathogenic microorganisms by self-degradation. Although trichinellosis a foodborne zoonotic disease, there are few reports on the interplay between Trichinella spiralissurvival strategies and autophagy-mediated host defense. Therefore, this study focused association T. spiralis of small intestinal cells. study, autophagy-related indexes cells after infection were detected using transmission electron microscopy,...
How to aid recovery from severe skin injuries, such as burns, chronic or radiation ulcers, and trauma, is a critical clinical problem. Current treatment methods remain limited, the discovery of ideal wound-healing therapeutics has been focus research. Functional recombinant proteins basic fibroblast growth factor (bFGF) epidermal (EGF) have developed for repair, however, some disadvantages in their use remain. This study reports novel small peptide targeting receptor 2 IIIc (FGFR2IIIc)...
In malignancies, fibroblast growth factor receptors (FGFRs) signaling is reinforced through overexpression of factors (FGFs) or their receptors. FGFR2 has been proposed as a target for cancer therapy, because both the expression and activation are boosted in various malignant carcinomas. Although several chemicals have designed against FGFR2, they did not exhibit enough specificity might bring potential accumulated toxicity. this study, we developed an epitope peptide (P5) its cyclic...
Oxidative stress is detrimental to animals and can depress the growth performance regulate gene expression of animals. However, it remains unclear how oxidative regulates long noncoding RNAs (lncRNAs) mRNAs. Therefore, purpose this article was explore profiles lncRNAs mRNAs in liver piglets under stress. Here, we constructed a piglet model induced by diquat evaluated effects on antioxidant enzyme activity piglets. We also used RNA-Seq examine global The targets were enriched ontology (GO)...
As a new type of noncoding RNA, circular RNA (circRNA) is stable in cells and not easily degraded. This can also competitively bind miRNAs to regulate the expression their target genes. The role circRNA mechanism intestinal oxidative stress (OS) weaned piglets still unclear. In our research, diquat (DQ) was used induce OS small epithelial (IPEC-J2) construct an cell model. Mechanistically, dual luciferase reporter assays, fluorescence situ hybridization (FISH), western blotting were...
Background Interferon lambda receptor 1 (IFNLR1) is a type II cytokine that clings to interleukins IL-28A, IL29B, and IL-29 referred as III IFNs (IFN-λs). IFN-λs act through the JAK-STAT signaling pathway exert antiviral effects related preventing curing an infection. Although immune function of in virus invasion has been described, molecular mechanism IFNLR1 process unclear. Objectives The purpose this study was elucidate role pathogenesis treatment porcine reproductive respiratory syndrome...