A5057563092- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Heart Failure Treatment and Management
- Vitamin D Research Studies
- Mobile Health and mHealth Applications
- Inhalation and Respiratory Drug Delivery
- Pediatric health and respiratory diseases
- Family and Patient Care in Intensive Care Units
- Health Literacy and Information Accessibility
- Adolescent and Pediatric Healthcare
- Emergency and Acute Care Studies
- Congenital Diaphragmatic Hernia Studies
- Climate Change and Health Impacts
- Respiratory and Cough-Related Research
- Tracheal and airway disorders
- Air Quality and Health Impacts
- Congenital Heart Disease Studies
- Innovative Approaches in Technology and Social Development
- COVID-19 and healthcare impacts
- Maternal Mental Health During Pregnancy and Postpartum
- Helicobacter pylori-related gastroenterology studies
- Child and Adolescent Health
- Digital Mental Health Interventions
Centre Hospitalier Universitaire Sainte-Justine
2014-2025
Université de Montréal
2014-2024
McGill University
2023
Montreal Children's Hospital
2023
Children's Hospital of Eastern Ontario
2022
Hospital for Sick Children
2022
Brigham and Women's Hospital
2011-2015
Harvard University
2011-2015
Massachusetts General Hospital
2011-2013
British School at Rome
2013
We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new evidence topic areas that were not previously addressed.International consensus conference series involving 52 multidisciplinary international content experts PARDS four methodology from 15 countries, using methodology, implementation science.Not applicable.Patients with or...
Rationale: Stress is associated with asthma morbidity in Puerto Ricans (PRs), who have reduced bronchodilator response (BDR).Objectives: To examine whether stress and/or a gene regulating anxiety (ADCYAP1R1) BDR PR and non-PR children asthma.Methods: This was cross-sectional study of (percent change FEV1 after BD) 234 PRs ages 9–14 years asthma. We assessed child using the Checklist Children’s Distress Symptoms, maternal Perceived Scale. Replication analyses were conducted two cohorts....
Background Elevated markers of systemic and pulmonary inflammation are associated with failure to recover lung function following exacerbations in people cystic fibrosis (pwCF). Our aim was determine whether adjuvant oral prednisone treatment would improve recovery forced expiratory volume 1 s (FEV ) % pred CF not responding antibiotic therapy. Methods This a randomised, double-blind, placebo-controlled trial pwCF treated intravenous antibiotics for exacerbation. At day 7, those who had...
SARS-CoV-2 infection causing the novel coronavirus disease 2019 (COVID–19) has been responsible for more than 2.8 million deaths and nearly 125 infections worldwide as of March 2021. In 2020, World Health Organization determined that COVID–19 outbreak is a global pandemic. The urgency magnitude this pandemic demanded immediate action coordination between local, regional, national, international actors. mission, researchers require access to high-quality biological materials data from...
Rationale: Statins, or HMG-CoA reductase inhibitors, may aid in the treatment of asthma through their pleiotropic antiinflammatory effects.Objectives: To examine effect statin therapy on asthma-related exacerbations using a large population-based cohort.Methods: Statin users aged 31 years greater with were identified from Population-Based Effectiveness Asthma and Lung population, which includes data five health plans. exposure assessed over 24-month observation period. medication possession...
New evidence supports the use of supplemental vitamin D in prevention exacerbation asthma; however, optimal posology to sufficiently raise serum levels while maximising adherence is unclear. The objective was ascertain efficacy high-dose D3 increasing preschoolers with asthma and provide preliminary data on safety outcomes. We conducted a 7-month, triple-blind, randomised, placebo-controlled, pilot trial children aged 1–5 years viral-induced asthma. Participants were allocated receive two...
Abstract Background Having a primary care provider and continuous relationship may be important for asthma outcomes. In this study, we sought to determine the association between 1) having usual of (UPC) asthma-related emergency department (ED) visits hospitalization in Québec children with 2) UPC continuity Methods Population-based retrospective cohort study using provincial health administrative data, including 2-16 years old ( N = 39, 341). Exposures outcomes were measured from 2010-2011...
Summary Background and Objective Cross‐sectional gender differences in wheeze are well documented, but few studies have examined the gender‐specific risk factors for longitudinally. This study aims to identify gender‐ age‐specific from birth through adolescence. Methods The incidence of was ascertained every 6 months age 14 years a cohort consisting 499 children with parental history atopy. Gender‐ were identified generalized estimating equations. Results A total 454 (91.0%) 351 (70.3%)...
To compare the time to asthma-related readmissions between children with a previous ICU hospitalization for asthma and those non-ICU explore predictors of readmission in admitted ICU.Retrospective cohort study using pan-Canadian administrative inpatient database from April 1, 2008, March 31, 2014.All adult pediatric Canadian hospitals.Children 2-17 years old asthma.None.A total 26,168 were hospitalized 33,304 times during period. The was shorter group compared (median 27 mo vs 35 group)....
Statins are hypothesized to have beneficial effects in asthma management through their pleiotropic anti-inflammatory effects. Several studies examined this relationship, but yielded conflicting results. This study investigates the effect of statin use on asthma-related hospitalizations and/or emergency department (ED) visits, and whether relationship varies by concomitant inhaled corticosteroid (ICS) a large cohort patients.Subjects with asthma, recent history exacerbation, who were 18 years...