- Turbomachinery Performance and Optimization
- Oral microbiology and periodontitis research
- Heat Transfer Mechanisms
- Fluid Dynamics and Turbulent Flows
- Dental Health and Care Utilization
- Refrigeration and Air Conditioning Technologies
- Proteins in Food Systems
- Medical and Biological Ozone Research
- Advanced Cellulose Research Studies
- Nanoplatforms for cancer theranostics
- Diabetes and associated disorders
- Pickering emulsions and particle stabilization
- Dental Implant Techniques and Outcomes
- Real-time simulation and control systems
- Metallurgy and Material Science
- 3D Printing in Biomedical Research
- Computational Fluid Dynamics and Aerodynamics
- Growth Hormone and Insulin-like Growth Factors
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Salivary Gland Disorders and Functions
- Advanced Numerical Methods in Computational Mathematics
- Advanced Electron Microscopy Techniques and Applications
- Nutritional Studies and Diet
- Dysphagia Assessment and Management
Shanghai Jiao Tong University
2022-2025
Shanghai Ninth People's Hospital
2022-2025
Northwest A&F University
2024-2025
Qingdao University of Science and Technology
2025
National Clinical Research
2024
Shanghai Stomatological Hospital
2024
Beihang University
2022-2024
Beijing Haidian Hospital
2024
Abstract Unsteady blade row interaction (UBRI) has a large impact on performance in high-speed axial compressors. Thus, the influence of UBRI should be accurately predicted compressor routine design. In this study, unsteady rotor–stator transonic single-stage compressor, NASA Stage 35, is studied by steady and Reynolds-Averaged Navier–Stokes methods. First, analyzed. Periodic separation bubbles stator suction surface induced rotor wake are observed. Comparisons between results show that...
The practical efficacy of nanomedicines for treating solid tumors is frequently low, predominantly due to the elevated interstitial pressure within such that obstructs penetration nanomedicines. This increased originates from both liquid and stresses related an undeveloped vascular network excessive fibroblast proliferation. To specifically resolve issues tumor treatment, this study introduces a holistic "dual-faceted" approach. A treatment platform predicated on WS2/Pt Schottky...
Abstract Flows in compressors are extremely complex with various scales. Small-scale turbulence, middle-scale rotor–stator interaction (RSI), large-scale corner separation, and tip leakage flow should all be considered the simulation of compressors. Recently, a new hybrid Reynolds-averaged Navier–Stokes-large eddy (RANS-LES) strategy that modifies turbulent viscosity equation based on Kolmogorov energy spectrum, termed grid-adaptive (GAS) method, is proposed by our group to achieve high...
A novel approach utilizing neodymium-catalyzed coordinative chain transfer polymerization (CCTP) to construct end-functionalized polyisoprenes with distinct and regulatable functional groups at the α- ω-termini is presented.
Abstract Background In recent decades, the global life expectancy has risen notably to approximately 73.5 years worldwide, coinciding with a rapid growth in older adult population, which presents significant public health challenge promoting healthy aging and longevity. Objective This study aimed prospectively investigate link between edentulousness likelihood of reaching centenarian status among individuals aged 80 older. Methods Data from Chinese Longitudinal Healthy Longevity Survey were...
Photodynamic therapy (PDT) is long-standing suffered from elevated tumor interstitial fluid pressure (TIFP) and prevalent hypoxic microenvironment within the solid malignancies. Herein, sound-activated flexocatalysis developed to overcome dilemma of PDT through both enhancing penetration photosensitizers by reducing TIFP establishing an oxygen-rich microenvironment. In detail, a Schottky junction constructed flexocatalyst MoSe
Immunotherapy stands as a groundbreaking strategy for cancer treatment, due to its ability precisely and safely detect eradicate tumors. However, the efficacy of immunotherapy is often limited by tumor autophagy, natural defense mechanism that tumors exploit resist immune attacks. Herein, we introduce spatiotemporally controlled method modulate autophagy via sonocatalysis, aiming improve immunotherapeutic outcomes. Specifically, synthesized tumor-targeting nanocatalyst based on semiconductor...
Previous studies have shown that abnormal metabolic reprogramming in CD4+ T cells could explain the occurrence of several autoimmune disorders, including Sjogren's syndrome (SS). However, therapeutic targets metabolism remain to be explored. Here, we report glutaminase 1 (Gls1), a pivotal factor glutaminolysis, might involved pathogenesis SS. The expression Gls1 was upregulated infiltrated labial and circulating SS patients. Inhibiting with BPTES significantly abolished proliferation rate,...
Abstract Aim Although poor oral health has been a potentially modifiable risk for mortality, the precise association between functional tooth units (FTUs) and premature death as well underlying mechanisms remains unclear. Methods This study used data from National Health Nutrition Examination Survey (NHANES) 2009–2018. Mortality details were obtained Death Index (NDI). The number of FTUs was defined pairs opposing natural artificial teeth in premolar molar area. Weighted logistic regression...
Abstract Background Periodontitis is strongly associated with type 2 diabetes (T2D) that results in serious complications and mortality. However, the pathogenic role of periodontitis development T2D underlain mechanism have not been fully elucidated. Methods A Mendelian randomization (MR) was performed to estimate causality between two diseases. Bioinformatics tools, including gene ontology pathway enrichment analyses, were employed analyze common differentially expressed genes (DEGs) T2D....
Abstract Aim Depression is prevalent among older adults. Although the number of missing teeth considered to be associated with depression, relationship between masticatory function, which usually indicated by functional tooth units (FTUs), and depression in adults remains unclear. Materials Methods This study used data from National Health Nutrition Examination Survey (NHANES) 2009–2018. The FTUs was defined as pairs opposing natural artificial teeth. accessed using Patient Questionnaire...
Abstract Flows in compressors are extremely complex with various scales. Small-scale turbulence, middle-scale rotor-stator interaction, large-scale corner separation and tip leakage flow, should all be considered the simulation of compressors. Recently, a new hybrid RANS-LES strategy that modifies turbulent viscosity equation based on Kolmogorov energy spectrum termed grid-adaptive (GAS) method, is proposed by our group to achieve high accuracy using different grid resolutions. In this...
Tip leakage flow (TLF) is an important structure in the compressor, and it has a significant effect on efficiency stability of compressor. In this study, dynamic mode decomposition (DMD) used to study spatiotemporal tip compressor rotor. The high-fidelity field calculated via delayed-detached eddy simulation (DDES) axial rotor as input dataset for DMD algorithm. results show that unsteady motion vortex (TLV) quite different at its generation, development, dissipation phases. Additionally,...
Tip leakage flow (TLF) is an important structure in the compressor, and it has a significant effect on efficiency stability of compressor. In our study, dynamic mode decomposition (DMD) used to study spatiotemporal tip compressor rotor. The high-fidelity field calculated via delayed-detached eddy simulation (DDES) axial rotor as input dataset for DMD algorithm. results show that unsteady motion vortex (TLV) quite different at its generation, development, dissipation phases. Additionally,...
The choice of numerical methods, including turbulence model and rotor-stator interface (RSI) treatments method largely affects the Reynolds-averaged Navier-Stokes (RANS) simulation multistage compressor. This paper presents a study TUDa-GLR-OpenStage compressor using shear stress transport (SST) SST-Helicity model. In addition, validations for treatment unsteady sliding mesh nonlinear harmonic methods (NLH), are also conducted to effect on flow field. Results show that is most significant....