A5068978741- Photoreceptor and optogenetics research
- Neural dynamics and brain function
- Retinal Development and Disorders
- Neuroscience and Neuropharmacology Research
- Neuroscience and Neural Engineering
- CAR-T cell therapy research
- Infant Health and Development
- Molecular Communication and Nanonetworks
- Innovative Educational Technologies
- Attachment and Relationship Dynamics
- Lymphoma Diagnosis and Treatment
- Neuroendocrine regulation and behavior
- Education and Social Development in Ukraine
- Cancer Immunotherapy and Biomarkers
- Educational Methods and Teacher Development
Weizmann Institute of Science
2021-2024
Pedagogical University
2016
Tel Aviv Sourasky Medical Center
2016
Abstract The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its vast and diverse connections with cortical subcortical structures. Understanding the patterns synaptic connectivity that comprise mPFC local network is crucial for deciphering how this circuit processes information relays it to downstream To elucidate organization mPFC, we developed high-throughput optogenetic method mapping large-scale functional in acute brain slices. We show male mice,...
Abstract Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how activity such connections contributes to behavior requires efficient methods for reversibly manipulating their function. Chemogenetic and optogenetic tools, acting endogenous G-protein-coupled receptor pathways, can be used modulate synaptic transmission, but existing tools are limited in sensitivity, spatiotemporal precision or spectral...
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how activity such connections contributes to behavior requires efficient methods for reversibly manipulating their function. Chemogenetic and optogenetic tools, acting endogenous G-protein coupled receptor (GPCRs) pathways, can be used modulate synaptic transmission, but existing tools are limited in sensitivity, spatiotemporal precision, or spectral...
Abstract Information is carried between brain regions through neurotransmitter release from axonal presynaptic terminals. Understanding the functional roles of defined neuronal projection pathways in cognitive and behavioral processes requires temporally precise manipulation their activity vivo . However, existing optogenetic tools have low efficacy off-target effects when applied to terminals, while chemogenetic are difficult control space time. Here, we show that a targeting-enhanced...
Abstract The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its vast and diverse connections with cortical subcortical structures. Understanding the patterns synaptic connectivity that comprise mPFC local network is crucial for deciphering how this circuit processes information relays it to downstream To elucidate organization mPFC, we developed high-throughput optogenetic method mapping large-scale functional connectivity. We show neurons project...
Abstract Oxytocin is essential in shaping social behavior across the lifespan. While role of oxytocin signaling parental care has been widely investigated, little known about its function during early life. This partly due to lack precise technologies for studying developing brain. Here, we studied pup under acute separation from and reunion with mother. We show that activity neurons was increased by maternal returned baseline after reunion. Behaviorally, maternally-separated pups emitted...