A5090677179- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Uterine Myomas and Treatments
- Menopause: Health Impacts and Treatments
- Estrogen and related hormone effects
- Endometrial and Cervical Cancer Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Ovarian function and disorders
- Intestinal and Peritoneal Adhesions
- Pelvic floor disorders treatments
- Cancer Risks and Factors
- Pregnancy-related medical research
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Reproductive Health and Technologies
- Phytoestrogen effects and research
- Ovarian cancer diagnosis and treatment
- Hormonal and reproductive studies
- Reproductive Health and Contraception
- Folate and B Vitamins Research
- Female Genital Mutilation/Cutting Issues
- Omental and Epiploic Conditions
- Prenatal Screening and Diagnostics
- Pain Management and Treatment
Vrije Universiteit Amsterdam
2001-2024
Amsterdam University Medical Centers
2018-2024
Amsterdam UMC Location University of Amsterdam
2023-2024
University of Amsterdam
2001-2023
University of Groningen
2021
Alrijne Ziekenhuis
2021
Rijnstate Hospital
2021
Gelre Hospitals
2021
Endometriosis
2021
Einstein Healthcare Network
2021
How should endometriosis be diagnosed and managed based on the best available evidence from published literature?The current guideline provides 109 recommendations diagnosis, treatments for pain infertility, management of disease recurrence, asymptomatic or extrapelvic disease, in adolescents postmenopausal women, prevention association with cancer.Endometriosis is a chronic condition plethora presentations terms not only occurrence lesions, but also presence signs symptoms. The most...
Pregnancy rates among infertile women have been reported to increase after hysterosalpingography, but it is unclear whether the type of contrast medium used (oil-based or water-soluble contrast) influences this potential therapeutic effect.
Abstract STUDY QUESTION Does incisional endometriosis (IE) harbor somatic cancer-driver mutations? SUMMARY ANSWER We found that approximately one-quarter of IE cases somatic-cancer mutations, which commonly affect components the MAPK/RAS or PI3K-Akt-mTor signaling pathways. WHAT IS KNOWN ALREADY Despite classification as a benign gynecological disease, it shares key features with cancers such resistance to apoptosis and stimulation angiogenesis is well-established precursor clear cell...
Abstract Fibroids are benign tumours of the myometrium and most common gynaecologic abnormality. Although fibroids asymptomatic, they can cause symptoms like heavy menstrual bleeding, pelvic pain, sexual dysfunction, pressure complaints, infertility. The association between infertility has been debated for decades. It is generally acknowledged that closer fibroid to uterine cavity endometrium lining, more unfavourable effect it might have on fertility, reducing odds successful implantation...
Abstract —Currently raloxifene, a selective estrogen receptor modulator, is being investigated as potential alternative for postmenopausal hormone replacement to prevent osteoporosis and cardiovascular disease. We compared the 2-year effects of raloxifene on wide range risk factors with those placebo conjugated equine estrogens (CEEs). Analyses were based 56 hysterectomized but otherwise healthy women aged 54.8±3.5 (mean±SD) years who entered this double-blind study randomly assigned...
Abstract STUDY QUESTION What is the influence of dietary interventions, namely low fermentable oligo-, di-, mono-saccharides, and polyols (Low FODMAP) diet endometriosis diet, on endometriosis-related pain quality life (QoL) compared to a control group? SUMMARY ANSWER After adhering intervention for 6 months, women with reported less an improved QoL baseline whereas, group, they bloating better in 3 11 domains. WHAT IS KNOWN ALREADY Standard treatment can be insufficient or may accompanied...
Objective: To investigate the effects of oral 17β-estradiol (E2) -dydrogesterone on fasting plasma homocysteine concentrations in healthy postmenopausal women. Methods: We studied 27 women who were assigned randomly to either a treatment group (n = 14) or control 13). During first 12 months study, consisted E2, 1 mg daily, combined sequentially with dydrogesterone 5 10 (14 days per 28-day cycle). Thereafter, treated E2,2 dydrogesterone, daily cycle) for period 3 months. The received no...
Abdominal wall endometriosis (AWE) is defined as endometrial tissue that superficial to the peritoneum. AWE often difficult diagnose, mimicking a broad spectrum of diseases. The aim this study was describe appearance on magnetic resonance (MR) imaging.We present ten patients with (12 lesions) in which MR imaging used for diagnosis. included T2-weighted and T1-weighted fat suppression. To assess value diffusion-weighted (DWI) endometriosis, four underwent additional DWI. apparent diffusion...
Abstract STUDY QUESTION Does hysterosalpingo-foam sonography (HyFoSy) lead to similar pregnancy outcomes, compared with hysterosalpingography (HSG), as first-choice tubal patency test in infertile couples? SUMMARY ANSWER HyFoSy and HSG produce findings a majority of patients clinical management based on the results either or HSG, leads comparable outcomes. is experienced significantly less painful. WHAT IS KNOWN ALREADY Traditionally, testing during fertility work-up performed by HSG. an...