A5008744908- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Health and Technologies
- Reproductive Biology and Fertility
- Gynecological conditions and treatments
- Gestational Trophoblastic Disease Studies
- Reproductive System and Pregnancy
- Reproductive Health and Contraception
- Endometriosis Research and Treatment
- Maternal and fetal healthcare
- Appendicitis Diagnosis and Management
- Prenatal Screening and Diagnostics
- Delphi Technique in Research
- Family Dynamics and Relationships
- Pregnancy and Medication Impact
- Pregnancy-related medical research
- Reproductive tract infections research
- Viral-associated cancers and disorders
- Ethics and Legal Issues in Pediatric Healthcare
- Immune Cell Function and Interaction
- Maternal and Perinatal Health Interventions
- Pelvic floor disorders treatments
- Meta-analysis and systematic reviews
- Autoimmune and Inflammatory Disorders Research
University of Amsterdam
2014-2024
Amsterdam University Medical Centers
2019-2024
Amsterdam UMC Location University of Amsterdam
2009-2019
Catharina Ziekenhuis
2016
Radboud University Medical Center
2016
Radboud University Nijmegen
2016
Sint Lucas Andreas Hospital
2016
University Medical Center Utrecht
2016
Maastricht University
2016
RELX Group (Netherlands)
2012
Chronic granulomatous disease (CGD) is an inherited disorder of phagocyte function in which defective superoxide production results deficient microbicidal activity. CGD patients suffer from recurrent, life-threatening infections, and nearly half develop chronic gastrointestinal (GI) complications (colitis, gastric outlet obstruction, or perirectal abscess) and/or autoimmune/rheumatologic disorders (AIDs). To identify genetic modifiers severity, we studied a cohort 129 patients, whom seven...
STUDY QUESTIONWhat is the treatment success rate of systemic methotrexate (MTX) compared with expectant management in women an ectopic pregnancy or a unknown location (PUL) low and plateauing serum hCG concentrations?
Abstract STUDY QUESTION Does endometrial scratching in women with one failed IVF/ICSI treatment affect the chance of a live birth subsequent fresh cycle? SUMMARY ANSWER In this study, 4.6% more births were observed scratch group, likely certainty range between −0.7% and +9.9%. WHAT IS KNOWN ALREADY Since first suggestion that might improve embryo implantation during IVF/ICSI, many clinical trials have been conducted. However, due to limitations sample size study quality, it remains unclear...
Is IVF with frozen-thawed blastocyst transfer (freeze-all strategy) more effective than fresh and (conventional strategy)?The freeze-all strategy was inferior to the conventional in terms of cumulative ongoing pregnancy rate per woman.IVF without embryos, thus embryo only strategy), is increasingly being used clinical practice because a presumed benefit. It still unknown whether this new increases efficacy.A single-centre, open label, two arm, parallel group, randomised controlled...
What are the obstetric and neonatal risks for women conceiving via frozen-thawed embryo transfer (FET) during a modified natural cycle compared with an artificial method.A follow-up study to ANTARCTICA randomized controlled trial (RCT) (NTR 1586) conducted in Netherlands, which showed that FET (NC-FET) was non-inferior (AC-FET) terms of live birth rates. The current collected data on outcomes 98 who had singleton birth. main outcome birthweight; additional included hypertensive disorder...
Abstract STUDY QUESTION Does hysterosalpingo-foam sonography (HyFoSy) lead to similar pregnancy outcomes, compared with hysterosalpingography (HSG), as first-choice tubal patency test in infertile couples? SUMMARY ANSWER HyFoSy and HSG produce findings a majority of patients clinical management based on the results either or HSG, leads comparable outcomes. is experienced significantly less painful. WHAT IS KNOWN ALREADY Traditionally, testing during fertility work-up performed by HSG. an...
Abstract The endometrial microbiota composition may be associated with implantation success. However, a ‘core’ has not yet been defined. This exploratory study analysed the by 16S rRNA sequencing (V1–V2 region) of 141 infertile women whose first IVF/ICSI cycle failed and compared profiles without live birth within 12 months follow-up, infertility cause type. Lactobacillus was most abundant genus in majority samples. Women to those had significantly higher crispatus relative abundance (RA) (p...
Abstract Introduction Implantation failure after transferring morphologically “good‐quality” embryos in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) may be explained by impaired endometrial receptivity. Analyzing the transcriptome analysis reveal underlying processes and could help guiding prognosis using targeted interventions for infertility. This exploratory study investigated whether profile was associated with short‐term or long‐term implantation outcomes (ie success...
Success rates of assisted reproductive techniques (ART) are approximately 30%, with the most important limiting factor being embryo implantation. Mechanical endometrial injury, also called 'scratching', has been proposed to positively affect chance implantation after transfer, but currently available evidence is not yet conclusive. The primary aim this study determine effect scratching prior a second fresh in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycle on live birth...
Tubal pathology is a causative factor in 20% of subfertile couples. Traditionally, tubal testing during fertility work-up performed by hysterosalpingography (HSG). Hysterosalpingo-foam sonography (HyFoSy) new technique that thought to have comparable accuracy as HSG, while it less expensive and more patient friendly. HyFoSy would be an acceptable alternative for provided has similar effectiveness terms outcomes.We aim compare the costs management guided or HSG. Consenting women will undergo...