A5068071862- Obesity, Physical Activity, Diet
- Pharmacological Receptor Mechanisms and Effects
- COVID-19 Clinical Research Studies
- Nutrition and Health in Aging
- Dental Research and COVID-19
- Breastfeeding Practices and Influences
- Gestational Diabetes Research and Management
- Health and Lifestyle Studies
- SARS-CoV-2 detection and testing
- Statistical Methods and Inference
- Cleft Lip and Palate Research
- Social Media in Health Education
- Substance Abuse Treatment and Outcomes
- Mobile Health and mHealth Applications
- Language Development and Disorders
- Long-Term Effects of COVID-19
- Cardiovascular Health and Risk Factors
- Cutaneous Melanoma Detection and Management
- Dental Health and Care Utilization
- SARS-CoV-2 and COVID-19 Research
- Tryptophan and brain disorders
- HIV, Drug Use, Sexual Risk
- Parathyroid Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Cardiac Health and Mental Health
University of Kentucky
2020-2025
Poliomyelitis Research Foundation
2024
Delaware County Memorial Hospital
2024
University of Alaska Anchorage
2024
University of Louisville
2024
Google (United States)
2019-2020
University of North Carolina at Chapel Hill
2015-2019
Albert Einstein College of Medicine
2016
COVID-19 may cause respiratory distress syndrome and death. Treatment of to prevent complications remains a priority.Our investigation sought determine whether combination spironolactone sitagliptin could reduce mortality for inpatients with SARS-CoV-2 infection.This single-blind, 4-arm, prospective randomized clinical trial was conducted at Shiraz Bushehr University Medical Sciences hospitals between December 2020 April 2021. We hospitalized adult patients pneumonia into 4 groups: control,...
Objective Buprenorphine is a medication for opioid use disorder that reduces mortality. This study aims to investigate the less well-understood relationship between dose in early stages of treatment and subsequent risk death. Methods We used Kentucky prescription monitoring data identify adult residents initiating transmucosal buprenorphine (January 2017 November 2019). Average daily days covered first 30 was categorized as ≤8 mg, >8 ≤16 >16 mg. Patients were followed 365 after...
This study aimed to compare microbial and inflammatory profiles in periodontally/systemically healthy African American (AA) Caucasian (C) individuals.
<sec> <title>BACKGROUND</title> Colon cancer is a leading cause of cancer-related deaths worldwide, and survival outcomes are influenced by variety factors, including biological traits, treatment type, patient characteristics. Traditional statistical models, such as Kaplan-Meier curves, have been widely used to estimate probabilities. However, these models often difficulty handling complex interactions, covariates, non-linear relationships between risk factors. Recently, machine learning...
High intakes of dietary phosphorus (P), relative to calcium (Ca) intake, are associated with a lower calcium:phosphorus ratio (Ca:P) which potentially has adverse health effects, including arterial calcification, bone loss, and death. A substantial percentage older adults (50 70 71 plus years) who have higher risk fracture rate than younger typically low Ca that dominated by P from natural fortified foods, Ca:P ratios desirable. This investigation was undertaken examine the resulting (by...
Background: Women with gestational diabetes mellitus (GDM) and their infants are at increased risk of developing metabolic disease; however, longer breastfeeding is associated a reduction in these risks. We tested an intervention to increase duration among women GDM. Materials Methods: conducted cluster randomized trial determine the efficacy education support program for were enrolled between 22 36 weeks pregnancy experimental lifestyle or wait-list control group. Breastfeeding intensity...
Wastewater surveillance provided early indication of COVID-19 in US municipalities. Residents long-term care facilities (LTCFs) experienced disproportionate morbidity and mortality the pandemic. We implemented LTCF building-level wastewater for SARS-CoV-2 at 6 Kentucky to provide warning populations considered vulnerable.This study aims evaluate performance LTCFs Kentucky.We conducted a mixed methods evaluation following Centers Disease Control Prevention (CDC) guidelines evaluating public...
Periodontal disease (PD) is prevalent in type 2 diabetic condition (T2DM). Objectives: We assessed the associations between serum or gingival crevicular fluid (GCF) endothelial and inflammatory mediators chronic PD among T2DM Hispanic adults. Methods: enrolled 248 Puerto Rican residents with aged 40–65 years. The exposures included (IL-1b, IL-6, IL-10, TNF-α), adhesion molecules, RANKL levels, GCF content of these analytes from a subset 158 samples. outcomes percent sites probing pocket...
Infection during pregnancy can result in adverse outcomes for both pregnant persons and offspring. Maternal vaccination is an effective mechanism to protect mother neonate into post-partum. However, our understanding of passive transfer antibodies elicited by maternal SARS-CoV-2 mRNA remains incomplete.We aimed evaluate the antibody responses engendered following initial booster doses circulation breastmilk better understand immunization newborn.We collected longitudinal blood samples from...
Abstract Purpose For the same reasons that rural telehealth has shown promise for enhancing provision of care in underserved environments, social media recruitment may facilitate more inclusive research engagement areas. However, little examined context, and few studies have evaluated feasibility using a free page to build network community members who be interested study. Here, we describe rationale, process, protocols developing implementing approach recruit residents participate an...
Background Sexual minority cisgender men and transgender (SMMT) individuals, particularly emerging adults (aged 18-34 years), often report hazardous drinking. Given that alcohol use increases the likelihood of HIV risk behaviors, disproportionately affects SMMT there is a need to test interventions reduce subsequent behaviors among this population. Ecological momentary (EMIs), which mobile phones deliver reduction messages based on current location can help address triggers lead drinking in...
Abstract Persons living in long-term care facilities (LTCFs) were disproportionately affected by COVID-19. We used wastewater surveillance to detect SARS-CoV-2 infection this setting collecting and testing 24-hour composite samples 2–4 times weekly at 6 LTCFs Kentucky, USA, during March 2021–February 2022. The routinely tested staff symptomatic exposed residents for using rapid antigen tests. Of 780 analyzed, 22% (n = 173) had detectable RNA. reported 161 positive (of 16,905) clinical signal...
Studies have suggested that obesity is linked within families and successful interventions involve both the parent child with obesity. However little information exists regarding similarities in adiposity weight loss between child, especially low socio-economic ethnically diverse households. The purpose of this study was to examine relationships changes from baseline over time adiposity, weight, health behaviors, self-efficacy children (n = 184) parents participating an 18-month program....
Purpose This study investigated vocabulary growth from 18 to 24 months of age in young children with repaired cleft palate (CP), otitis media, and typically developing (TD) children. In addition, the contributions factors such as hearing level, middle ear status, size consonant inventory, maternal education gender development expressive were explored. Method Vocabulary 40 CP, 29 25 TD was measured using parent report on MacArthur-Bates Communicative Development Inventories: Words Sentences...
The cumulative socioeconomic status (SES) model posits that childhood and adult experiences accumulate to influence disease risk. While individual SES indicators such as education income are independently associated with incident type 2 diabetes (T2D), the association of T2D is unclear, especially in African American adults.