- Advanced Neuroimaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Glaucoma and retinal disorders
- Functional Brain Connectivity Studies
- Brain Metastases and Treatment
- Vestibular and auditory disorders
- Autism Spectrum Disorder Research
- Neurological disorders and treatments
- Cardiovascular Health and Disease Prevention
- Moyamoya disease diagnosis and treatment
- MRI in cancer diagnosis
- Acute Ischemic Stroke Management
- Fetal and Pediatric Neurological Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Parkinson's Disease Mechanisms and Treatments
- Ophthalmology and Eye Disorders
- Lung Cancer Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Dementia and Cognitive Impairment Research
- Meningioma and schwannoma management
- Radiopharmaceutical Chemistry and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
Nara Medical University
2015-2024
Nara Medical University Hospital
2008-2022
Nagoya University
2015
Conclusions: The incident ratios of cochlear and/or vestibular endolymphatic hydrops (EH) were significantly higher in the affected ears patients with Meniere's disease (MD) than healthy controls. There no significant differences between controls and contralateral MDs. Objectives: aim was to compare incidence EH unilateral/bilateral MD using 3T magnetic resonance imaging (MRI) intravenous gadolinium. Methods: A total 41 diagnosed MD: 32 unilateral (uMD) nine bilateral (bMD). Fifteen...
Tract-based analysis can be used to investigate required tracts extracted from other fiber tracts. However, the fractional anisotropy (FA) threshold influences tractography analysis. The current study evaluated influence of FA in measuring diffusion tensor parameters for tract-based uncinate fasciculus subjects with Alzheimer disease (AD).Subjects included 30 patients AD and 10 healthy controls. We acquired tractographies by using different thresholds. measured mean apparent coefficient...
Cognitive remediation therapy (CRT) effectively reduces neurocognitive impairment in patients with schizophrenia, but few studies have used structural neuroimaging methods to assess its neuroanatomical effects. We investigated these effects, as well the association between changes cortical volume and performance. Between August 2013 September 2016, we performed a randomized controlled study comprising CRT group (16 individuals) treatment-as-usual (TAU) (15 of schizophrenia. participants...
Meniere's disease is a common disease, with an incidence of 15-50 per 100,000, that presents recurrent vertigo and cochlear symptoms. The pathology was first reported to involve endolymphatic hydrops in 1938. sac thought maintain the hydrostatic pressure endolymph homeostasis for inner ear. As surgical treatment intractable drainage intraendolymphatic application large doses steroids performed control preserve or improve ear function. In present study, observe effect this surgery, we...
<h3>BACKGROUND AND PURPOSE:</h3> Both clinical and imaging criteria must be met to diagnose neuromyelitis optica spectrum disorders multiple sclerosis. However, are often misdiagnosed as MS because of an overlap in MR features. The purpose this study was confirm differences between with visually detailed quantitative analyses large-sample data. <h3>MATERIALS METHODS:</h3> We retrospectively examined 89 consecutive patients (median age, 51 years; range, 16–85 females, 77; aquaporin 4...
Recently, 3-Tesla magnetic resonance imaging (MRI) with intravenous gadolinium injection has been used to reveal endolymphatic hydrops (EH). In the present study, we aimed evaluate EH in patients Meniere's disease (MD) objectively and quantitatively, compared space (ELS) individuals MD healthy controls, gain understanding of characteristics MD.Eighty-two unilateral (uMD), 16 bilateral (bMD), 47 volunteers were enrolled. All participants underwent 3-T MRI at 4 hours after injection. The...
In autism spectrum disorder (ASD), the complexity-specific hypothesis explains that atypical visual processing is attributable to selective functional changes in pathways. We investigated dendritic microstructures and their associations with connectivity (FC). Participants included 28 individuals ASD 29 typically developed persons. explored neurite orientation dispersion density imaging (NODDI) brain areas whose FC was significantly correlated NODDI parameters regions of interests....
<h3>BACKGROUND AND PURPOSE:</h3> Diffusion kurtosis is a statistical measure for quantifying the deviation of water diffusion profile from Gaussian distribution. The current study evaluated time course in patients with cerebral infarctions, including perforator, white matter, cortical, and watershed infarctions. <h3>MATERIALS METHODS:</h3> Subjects were 31 patients, representing 52 observations lesions. duration between onset imaging ranged 3 hours to 122 days. Lesions categorized into 4...
The integration of visual features is important for recognizing objects as a coherent whole, key domain difficulty in autism spectrum disorder (ASD). We tested the hypothesis that ASD patients exhibit difficulties facial emotional recognition via perceptual binding due to weak coherence. assessed 18 and 27 typically developing individuals their ability identify expressions from faces pictures moving behind narrow vertical horizontal slit. In this task, only single local piece information was...
The objective of this study was to determine long-term outcomes after stent placement for subclavian artery (SA) obstructive lesions assisted by intraoperative intravascular ultrasound (IVUS). included 25 in 24 patients who underwent IVUS stenosis or obstruction at our hospital between January 2003 and August 2010. Outcome evaluated based on the results within 30 postoperative days (technical success rate, improvement upper extremity ischemia, steal syndrome, left-right blood pressure...
Abstract Compared to typically developing (TD) children, people with autism spectrum disorder (ASD) have an increased risk of adverse childhood experiences (ACEs). Exposure ACEs is associated adult ASD psychological comorbidities, such as posttraumatic stress (PTSD). Occurrence intrusive event reexperiencing, characteristic PTSD, often causes social dysfunction in adults ASD, but its pathological basis unclear. This study examined brain regions related the severity reexperiencing and...
Background: Pathologically, Meniere's disease symptoms are considered to be associated with endolymphatic hydrops. Examinations revealing hydrops can useful for accurate diagnosis. We previously reported a quantitative method evaluating hydrops, i.e., by measuring the volume of space using three-dimensional magnetic resonance imaging (MRI) inner ear. This study aimed confirm usefulness our methods diagnosing disease. Here, we extracted new explanatory factors comparing between healthy...
Purpose: To examine whether carotid artery stenting (CAS) of stenoses with unstable plaque using a closed-cell stent-in-stent technique prevents protrusion. Materials and Methods: Between December 2014 August 2018, 35 consecutive patients (mean age 75.8 years; 29 men) stenosis (20 symptomatic) diagnosed by magnetic resonance imaging were prospectively analyzed. Mean diameter was 83.5%. All CAS procedures performed placement Carotid Wallstents an embolic protection device conservative...
Patients with Parkinson's disease (PD) often experience pain, which fluctuates in "on" and "off" states, but the underlying mechanism is unclear. The nucleus accumbens (NAc) a central component of mesolimbic dopaminergic pathway involved pain processing. We conducted resting-state functional magnetic resonance imaging (rsfMRI) analysis to explore relationship between neuronal synchronization NAc pain-related brain regions intensity states. assessed 23 patients sporadic PD based on rsfMRI...
Individuals with autism spectrum disorder (ASD) have an increased risk of adverse childhood experiences (ACEs) than typically developed (TD) children. Since multiple lines studies suggested that ACEs are related to myelination in the frontal lobe, exposure can be associated white matter microstructural disruption which may implicated subsequential psychological deficits after adulthood. In this study, we investigated relationship between and integrity on lobe-related tracts using diffusion...