R. Gayman Helman

ORCID: 0000-0002-0567-7964
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About
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Research Areas
  • Veterinary Oncology Research
  • Microbial infections and disease research
  • Infectious Diseases and Mycology
  • Animal Disease Management and Epidemiology
  • Vector-Borne Animal Diseases
  • Veterinary Equine Medical Research
  • Bird parasitology and diseases
  • Renal and related cancers
  • Veterinary Orthopedics and Neurology
  • Renal Diseases and Glomerulopathies
  • Drug-Induced Hepatotoxicity and Protection
  • Hedgehog Signaling Pathway Studies
  • Mycobacterium research and diagnosis
  • Sarcoma Diagnosis and Treatment
  • Vector-borne infectious diseases
  • Cell Adhesion Molecules Research
  • Liver Disease Diagnosis and Treatment
  • T-cell and Retrovirus Studies
  • Toxoplasma gondii Research Studies
  • Wildlife Ecology and Conservation
  • Trace Elements in Health
  • Biosensors and Analytical Detection
  • SARS-CoV-2 and COVID-19 Research
  • Veterinary Medicine and Surgery
  • Animal testing and alternatives

Hebrew University of Jerusalem
2020-2021

Wellborn Road Veterinary Medical Center
2020

Oklahoma State University
1997-2002

Oklahoma State University Oklahoma City
2000

American College of Veterinary Pathologists
2000

Texas A&M University
1979-1999

ASM International
1999

The Ohio State University
1999

University of Minnesota
1999

Mitchell Institute
1998

10.1016/j.cmi.2020.06.009 article EN publisher-specific-oa Clinical Microbiology and Infection 2020-06-23

Pooling multiple swab samples before RNA extraction and real-time reverse transcription polymerase chain reaction (RT-PCR) analysis has been proposed as a strategy to reduce costs increase throughput of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tests. However, reports on practical large-scale group testing for SARS-CoV-2 have scant. Key open questions concern reduced sensitivity due sample dilution, the rate false positives, actual efficiency (number tests saved by...

10.1126/scitranslmed.abf2823 article EN cc-by Science Translational Medicine 2021-02-22

One hundred three bovine samples submitted to the Oklahoma Animal Disease Diagnostic Laboratory (OADDL) that were positive for viral diarrhea virus (BVDV) typed by a nested reverse transcription-polymerase chain reaction BVDV genotypes. These included supernatants from isolation (79), serums (17), and buffy coats (7). The biotype, cytopathic (CP) or noncytopathic (NCP), was determined cell culture isolation. Twenty-eight of 103 herd screening BVDV, 32 OADDL necropsy cases, 43 live cattle...

10.1177/104063870001200106 article EN Journal of Veterinary Diagnostic Investigation 2000-01-01

Objective To document clinical signs and gross pathologic changes associated with naturally acquired cantharidiasis (blister beetle poisoning) in equids. Design Retrospective study. Animals 70 equids laboratory-confirmed blister poisoning. Procedure Medical records were reviewed to obtain history, physical examination findings, feeding practices, diagnostic test necropsy results. Results 32 horses 2 donkeys died from exposure cantharidin, whereas 36 survived. Diet content varied, but alfalfa...

10.2460/javma.1997.211.08.1018 article EN Journal of the American Veterinary Medical Association 1997-10-15

Abstract Objective To determine features of a new form hereditary nephritis (HN) in dogs. Animals Parents and 16 first-generation offspring (8 males, 8 females). Procedure Adolescent dogs that developed renal failure were euthanatized necropsied. Unaffected monitored until they at least 2 years old. Studies included light electron microscopy kidneys obtained from affected unaffected immunolabeling for collagen-IV chains epidermal basement membranes (BM). The nucleotide sequence portion exon...

10.2460/ajvr.1999.60.03.373 article EN American Journal of Veterinary Research 1999-03-01

Ocular contents from a horse with 4-week history of severe unilateral uveitis were submitted for histopathologic examination. A granulomatous chorioretinitis intralesional Halicephalobus deletrix was diagnosed. The developed progressive neurologic signs several days following the surgery to remove ocular and implant prosthesis subsequently euthanatized. multifocal encephalitis H. deletrix, localized primarily optic chiasm, thalamus, brain stem, diagnosed tissues acquired at necropsy. other...

10.1177/030098589503200514 article EN Veterinary Pathology 1995-09-01

Parasitic nematodes that infect quail have been understudied and long dismissed as a problem in management. Within the Rolling Plains ecoregion of Texas, an area has experienced population "boom bust" cycles ultimately general decline, need to determine why Northern bobwhite (Colinus virginianus) populations are diminishing increased priority. Previously, caecal parasites documented cause inactivity, weight loss, reduced growth, inflammation mucosa, even death. The worm Aulonocephalus...

10.1016/j.ijppaw.2017.02.001 article EN cc-by-nc-nd International Journal for Parasitology Parasites and Wildlife 2017-02-24

10.1177/030098588402100218 article EN Veterinary Pathology 1984-03-01

A 6-year-old cat was examined because of recurrence a draining mass involving skin and subcutaneous tissues the caudoventral aspect abdomen. Previous treatment included administration antimicrobial drugs corticosteroids surgical excision. Atypical mycobacteria were seen during cytologic examination biopsy specimens mass; Nocardia sp cultured. While hospitalized, developed hypercalcemia found to have high serum calcitriol concentrations. Treatment consisted ciprofloxacin...

10.2460/javma.1999.215.07.959 article EN Journal of the American Veterinary Medical Association 1999-10-01

Enteric pythiosis was diagnosed in nine dogs Oklahoma. Eight had anorexia and weight loss. Two of these diarrhea; two exhibited vomiting one dog vomiting. One presented with dysphagia. Seven either a palpable or radiographically visible abdominal mass. These seven localized regions mucosal ulceration thickened gastric intestinal walls some involvement the adjacent mesentery omentum. enlarged regional mesenteric lymph nodes. that dysphagia an oropharyngeal mass involving larynx cranial...

10.5326/15473317-35-2-111 article EN Journal of the American Animal Hospital Association 1999-03-01

Recognition of hepatozoonosis in four dogs that lived Oklahoma their entire lifetimes documents expansion the previously recognized endemic area disease. Salient clinical features are fever, marked neutrophilic leukocytosis, periosteal new bone proliferation, myalgia, weakness, muscle and generalized wasting, lack response to treatment. Transient, large-bowel diarrhea may be observed. Each cases had signs compatible with chronic, persistent inflammatory disease were poorly ultimately...

10.5326/15473317-33-3-221 article EN Journal of the American Animal Hospital Association 1997-05-01

Eight calves were inoculated into the bronchus with H. somnus. Thirteen bovine respiratory syncytial virus (BRSV) and 8 days later All developed necrotizing, suppurative, lobular bronchopneumonia pleuritis. Clinical signs of disease pneumonic lesions significantly more severe in that sequentially BRSV followed by Pneumonic similar to those described for naturally occurring somnus-associated tract disease. Control alone or sham-inoculated medium did not develop clinical The BRSV-inoculated...

10.1177/030098588802500204 article EN Veterinary Pathology 1988-03-01

Renal disease affecting 3 male and 1 female English Cocker Spaniels was studied. Clinical features of the included proteinuria progressive deterioration renal function. Dogs were 11 to 27 months old when euthanized because severe chronic failure. Grossly, cortices thin. Light microscopic evaluation revealed diffuse glomerular characterized by mesangial thickening, fibrosis, periglomerular obsolescence. Based on these clinical pathologic features, familial nephropathy suspected despite fact...

10.1111/j.1939-1676.1997.tb00077.x article EN other-oa Journal of Veterinary Internal Medicine 1997-03-01

Three adult horses underwent aggressive treatment of squamous cell carcinoma the nasal cavity and paranasal sinuses, using course-fractionated cobalt 60 radiotherapy. Squamous sinuses is not commonly diagnosed in horses. Historically, with this type neoplasm have been treated or undergone some form surgery. The prognosis for long-term survival cure has poor. Long-term results radiotherapy were good to excellent exceeded those usually reported surgically. On basis these results, use neoplasms...

10.2460/javma.1998.212.06.848 article EN Journal of the American Veterinary Medical Association 1998-03-15

Two litters of English cocker spaniels (ECSs) produced by familial nephropathy (FN) carriers were evaluated to characterize the early features this disease. Three puppies developed FN. Proteinuria, which began when these five-to-eight months old, was first abnormality detected. Proteinuria persisted while each puppy's growth rate slowed, and renal function gradually deteriorated. The interval from onset proteinuria development azotemia two-to-nine months. Characteristic glomerular capillary...

10.5326/15473317-34-3-189 article EN Journal of the American Animal Hospital Association 1998-05-01

Squamous cell carcinoma of the canine nasal cavity and frontal sinus was diagnosed in eight cases between May 1988 April 1994. The most common presenting complaints were discharge, including epistaxis; sneezing; facial deformity or exophthalmos. Metastasis not identified any case, but bone lysis invasion into tissues outside noted five cases. Computed tomograms performed more useful than radiographs determining extent neoplastic involvement. Euthanasia within one week diagnosis three at...

10.5326/15473317-32-2-103 article EN Journal of the American Animal Hospital Association 1996-03-01

Squamous cell carcinoma of the nasal planum was diagnosed in eight dogs between March 1988 and January 1994. Epistaxis, sneezing, ulceration or swelling were most common presenting complaints. Although no evidence metastasis identified, primary tumor all cases locally invasive with extensive involvement underlying tissues. Advanced imaging procedures performed three indicated that physical examination may underestimate local extent neoplasm. Euthanasia six due to progressive neoplastic...

10.5326/15473317-31-5-373 article EN Journal of the American Animal Hospital Association 1995-09-01

Summary Concurrent bacterial culturing of duodenal/proximal jejunal fluid and duodenal mucosa was performed on 2 occasions in each 16 IgA-deficient German Shepherd Dogs with small intestinal overgrowth. The interval between sample collections dog 74 to 78 days. Species bacteria numbers colony-forming units ( cfu ) per milliliter were compared species found the concurrent sample. There inconsistent correlation for number minimal isolated from sites. Fewer usually than When same numeric...

10.2460/ajvr.1994.55.07.957 article EN American Journal of Veterinary Research 1994-07-01
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