A5035969590- Monoclonal and Polyclonal Antibodies Research
- Virus-based gene therapy research
- Bacteriophages and microbial interactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Silk-based biomaterials and applications
- Nanoplatforms for cancer theranostics
- Gold and Silver Nanoparticles Synthesis and Applications
- Microplastics and Plastic Pollution
- Electrowetting and Microfluidic Technologies
- Diatoms and Algae Research
- Advancements in Transdermal Drug Delivery
- Microfluidic and Bio-sensing Technologies
- RNA Interference and Gene Delivery
- Advanced Sensor and Energy Harvesting Materials
- Recycling and Waste Management Techniques
- Nanomaterials for catalytic reactions
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
- Advanced Fluorescence Microscopy Techniques
- Immunotherapy and Immune Responses
- Lipid Membrane Structure and Behavior
- 3D Printing in Biomedical Research
- Nanoparticle-Based Drug Delivery
- Cancer Research and Treatments
- Thermochemical Biomass Conversion Processes
Suzhou University of Science and Technology
2024
Zhejiang University
2022-2024
Xiamen University
2021-2022
Collaborative Innovation Center of Chemistry for Energy Materials
2021
Lipid nanoparticles (LNPs), a nonviral nucleic acid delivery system, have shown vast potential for vaccine development and disease treatment. LNPs assist mRNA to cross physiological barriers such as cell membranes endosomes/lysosomes, promoting the intracellular presentation of mRNA. However, endosome escape efficiency biosafety currently commercialized are still unsatisfactory, resulting in underutilization Herein, we report that fluorinated modification...
Abstract Advanced chemotherapeutic strategies including prodrug and nanocatalytic medicine have significantly advanced tumor‐selective theranostics, but delicate screening, tedious synthesis, low degradability/biocompatibility of inorganic components, unsatisfied reaction activity complicate treatment efficacies. Here, the intrinsic anticancer bioactivity liquid metal nanodroplets (LMNDs) is explored through galvanic replacement. By utilizing a mechano‐degradable ligand, resultant size...
Based on digital microfluidics, a highly-automated and integrated phage display platform (Auto-Panning) was developed for peptide screening.
The double monoclonal display (dm-Display) has realized highly efficient ligand screening, which can accelerate the whole process from weeks to 24 h with clone characterization throughput 1000-time higher than that of traditional approach.
Efficient molecular selection is a prerequisite for generating tools used in diagnosis, pathology, vaccinology, and therapeutics. Selection efficiency thermodynamically highly dependent on the dissociation equilibrium that can be reached single round. Extreme shifting of towards favors retention high-affinity ligands over those with lower affinity, thus improving efficiency. We propose to synergize dual effects by deterministic lateral-displacement microfluidics, including collision-based...