The current global water environment has been seriously damaged. prediction of quality parameters can provide effective reference materials for future conditions and improvement. In order to further improve the accuracy stability generalization ability model, we propose a new comprehensive deep learning algorithm. Firstly, data are cleaned pretreated by isolation forest, Lagrange interpolation method, sliding window average, principal component analysis (PCA). Then, one-dimensional residual...

Tolerogenic immunotherapy aims to blunt pathogenic inflammation without affecting systemic immunity. However, the anti-inflammatory drugs and immunosuppressive biologics that are used in clinic usually result nonspecific immune cell suppression off-target toxicity. For this reason, strategies have been developed induce antigen-specific tolerance through delivery of disease-relevant antigens by nanocarriers as a benefit their preferential internalization antigen-presenting cells. Herein, we...

High-fat (HF) diet-induced neuroinflammation and cognitive decline in humans animals have been associated with microbiota dysbiosis via the gut-brain axis. Our previous studies revealed that excretory-secretory products (ESPs) derived from larval Echinococcus granulosus ( E. ) function as immunomodulators to reduce inflammatory response, while parasitic infection alleviates metabolic disorders host. However, whether ESPs can improve impairment under obese conditions remain unknown. This...

Aqueous zinc-ion batteries (AZIBs) have attracted interest for their low cost and environmental friendliness. Two bipolar organic materials with different degrees of conjugation, pPMQT pNTQT, were rationally designed synthesized as cathode candidates AZIBs based on 4,4′-diaminotriphenylamine (TPA), 2,7-diaminoanthraquinone (AQ), two anhydrides. This molecular design features an increased conjugation electron cloud density, thereby improving charge transport kinetics, specific capacity,...

Abstract To increase the in vivo stability of cationic gene carriers and avoid adverse effects their positive charge, we synthesized a new shielding material by conjugating low molecular weight polyethylene glycol (PEG) to hyaluronic acid (HA) core. The HA-PEG conjugate assembled with positively charged complex, forming protective layer through electrostatic interactions. DNA/polyetherimide/HA-PEG (DNA/PEI/HA-PEG) nanoparticles had higher than both DNA/polyethyleneimine (DNA/PEI) DNA/PEI/HA...

Temperature-dependent microrheology of a concentrated charge-stabilized poly(methyl methacrylate) colloidal dispersion with different salt concentrations was investigated by diffusing wave spectroscopy in backscattering mode. The critical temperature where the system undergoes aggregation and gelation depends upon particle volume fraction or concentration. viscoelastic properties systems have been discussed using Maxwell Kelvin–Voigt models. crossover (G′ = G″) frequency has used to...

Parasitic infection improves metabolic homeostasis in "western diet"-induced obesity through the regulation of adipogenesis. However, underlying mechanism is not yet fully understood. Using microarray analysis, this study investigated long non-coding RNA (lncRNA) and messenger (mRNA) profiles subcutaneous adipose tissues from mice infected with Echinococcus granulosus protoscoleces. A total 1052 mRNA (541 upregulated, 511 downregulated) 220 lncRNA (126 94 transcripts were differentially...

Abstract Background Caucasian clover ( Trifolium ambiguum M. Bieb.) is a strongly rhizomatous, low-crowned perennial leguminous and ground-covering grass. The species may be used as an ornamental plant resistant to cold, arid temperatures grazing due well-developed underground rhizome system strong clonal reproduction capacity. However, the posttranscriptional mechanism of development in caucasian has not been comprehensively studied. Additionally, reference genome for this yet published,...

Abstract The forage species Caucasian clover ( Trifolium ambiguum M. Bieb.), a groundcover plant, is resistant to both cold and drought. However, reference genes for qRT-PCR-based analysis of are lacking. In this study, 12 were selected on the basis transcriptomic data. These used determine most stably expressed in various organs under cold, salt drought stress analysis. Reference gene stability was analyzed by geNorm, NormFinder, BestKeeper, ∆Ct method RefFinder. Under stress, RCD1 PPIL3...

Fusarium zanthoxyli is a destructive pathogen causing stem canker in prickly ash, an ecologically and economically important forest tree. However, the genome lack of F. has hindered research on its interaction with ash development precise control strategies for canker.

Abstract Glioblastoma is one of the most aggressive and treatment‐resistant forms primary brain cancer, posing significant challenges in effective therapy. This study aimed to enhance effectiveness glioblastoma therapy by developing a unique nanomedicine composed Pluronic F127‐complexed PEGylated poly(glutamic acid)‐cisplatin (PLG‐PEG/PF127‐CDDP). PLG‐PEG/PF127‐CDDP demonstrated an optimal size 133.97 ± 12.60 nm, facilitating efficient cell uptake GL261 glioma cells. In vitro studies showed...

Downward looking ground penetrating radar (GPR) has been considered a viable technology for landmine detection. For such GPR with the antennas positioned very close to surface, reflections from i.e., bounce, are strong and can completely dominate weak returns shallowly buried plastic mines. Hence, one of key challenges using GPRs detection is remove bounce as possible without altering return. In this paper, we first review existing removal algorithms. Then two newly devised adaptive...

Intermittent faults in electronic system will cause lots of uncertainty maintenance, lead to a waste time and money. There are lot factors that may intermittent faults. This paper has analyzed the causes faults, shows we can reduce this negative affect by using three status Markov model. Compare traditional model, new method also false alarms improve detection rate.

Void-layer detection and thickness determination in runways are studied this paper. is thin layer whose very small (usually less than 1cm). Firstly, the void-layer can be detected based on its time-frequency distribution characteristic- S transform. This first attempt of transform to used runways. In same time, depth evaluated spectrum optimisation inversion method, which impulse pair time domain corresponding upper bottom interface extracted EM wave propagation model improved system...

Abstract The development of high‐efficiency and good biocompatible photothermal therapy platforms is conducive to avoiding the risks nano‐preparations in vivo . poly‐L‐lactic acid (PLLA) indicated biodegradability biocompatibility. Inspired by natural melanin extraordinary nontoxic mussel biopolymer, polydopamine nanoparticles (PDA NPs) with efficacy have attracted increasing attention. Herein, we performed study blended PDA/PLLA coated PDA@PLLA electrospun nanofibers (ESNFs) for therapy. In...

In this paper, a non-homogeneous detector (NHD) is developed for ground penetrating radar (GPR) the first time. The homogeneousness of bounce (GB) and number position buried targets (or target-like objects) can be determined by general likelihood based NHD. Combined with NHD, principal components analysis (PCA) blind source extraction (BSE) methods are also presented GB removal, which referred to as NHD-PCA NHD-BSE algorithm, respectively. For PCA only taken on target areas avoid leakage...

Downward looking ground penetrating radar (GPR) has been considered a viable technology for landmine detection. For such GPR with the antennas positioned very close to surface, reflections from i.e., bounce, are strong and can completely dominate weak returns shallowly buried non-metallic mines. Hence, one of key challenges using GPRs detection is remove bounce as possible without altering return. The varies surface roughness soil conditions leads performance degradation many removal...

Stolt migration is one of the useful GPR imaging algorithms, which has ad- vantage fast implementation speed. The Fourier transform integral formula in image reconstruction realized by coordinate transformation and done through interpolation. Inter- polation determines efiectiveness directly. In practical applications, zero-flll interpolation time-domain used to improve accuracy, but will increase compu- tational complexity. this paper, non-uniform (NUFFT) algorithm introduced realize...

The fuel consumption performance of aircraft affects the deployment capacity and profitability airlines. This paper focus on building a reasonable exponential attenuation model based actual flight data. In consideration feature that flying distance varies with performance, RELAX-based algorithm is introduced method Non-homogeneousness Detect to attempt realize separation parameter estimation each component model. CRB analysis experiment results proved accuracy while A330 data showed...

Strong rebar echo which can't be eliminated in t−x domain directly will disturb the detection and discrimination of interested targets like cryptic disasters. This paper presents application Hyp-curvelet transform detecting suppressing echo. Echoes from different are concentrated their own apex coordinate but separated with each other space after transformed. The peak value indicates location target. With some algorithm rebar's could obtained, then its components can eliminated. In this way...