A5044101493- Heart Rate Variability and Autonomic Control
- Veterinary Equine Medical Research
- Cardiovascular and exercise physiology
- Neuroscience of respiration and sleep
- Veterinary Oncology Research
- Airway Management and Intubation Techniques
- Restraint-Related Deaths
- Blood Coagulation and Thrombosis Mechanisms
- Thermal Regulation in Medicine
- Platelet Disorders and Treatments
- Tracheal and airway disorders
- Pharmacological Effects and Assays
- Infectious Diseases and Mycology
- Neonatal Respiratory Health Research
- Hemodynamic Monitoring and Therapy
- Meat and Animal Product Quality
- Cephalopods and Marine Biology
- Respiratory Support and Mechanisms
- Veterinary Orthopedics and Neurology
- Cardiac electrophysiology and arrhythmias
- Antifungal resistance and susceptibility
- Congenital Diaphragmatic Hernia Studies
- Veterinary Medicine and Surgery
- Insect and Arachnid Ecology and Behavior
- Sports Performance and Training
Nihon University
2005-2024
The Schwarzman Animal Medical Center
2011-2015
Teikyo University
2014
Comprehensive Clinical Research
2000-2011
University of California, San Diego
1993-2003
Japan Racing Association
1994-1997
University of Veterinary Medicine
1991
Kaw Nation
1970
During exercise, pulse oximetry is problematic due to motion artifact and altered digital perfusion. New oximeter technology addresses these issues may offer improved performance. We simultaneously compared Nellcor N-395 (Oxismart XLTM) oximeters with an RS-10 forehead sensor (RS-10), a D-25 digit (D-25), the Ivy 2000 (Masimo SETTM)/LNOP-Adt (Ivy) arterial blood oxygen saturation (Sa O 2 ) by cooximetry. Nine normal subjects, six athletes, four patients chronic disease exercised maximum...
The incidence of DIC in 208 dogs with a malignant tumor was evaluated. 9.6% which solid all. In 164 tumor, the 12.2%. hemangiosarcoma, mammary gland carcinoma and adenocarcinoma lung significantly higher than that other tumors. These results suggested special care looking for should be taken tumor.
Acute hypoxia increases heart rate (HR) and cardiac output (Qt) at a given oxygen consumption (VO2) during submaximal exercise. It is widely believed that the underlying mechanism involves increased sympathetic activation circulating catecholamines acting on beta receptors. Recent evidence indicating continued role for parasympathetic modulation of HR moderate exercise suggests withdrawal plays part in increase Qt hypoxic To test this, we separately blocked beta-sympathetic arms autonomic...
Previous work has shown that replacing N2 in air with He at the same inspired O2 fraction reduces exercise-induced alveolar-arterial PO2 difference (AaPO2) horses but provided no mechanism explaining this effect. We sought to distinguish among possible causes by using multiple inert gas elimination technique. Six were studied on a high-speed treadmill while they breathed either ambient or normoxic He-O2. uptake reached 138.0 ml.min-1.kg-1 and was not affected Temperature-corrected arterial...
Exercise in normal human subjects causes deterioration of matching ventilation to blood flow the lungs, but only about 50% those examined. A previous study (Wagner et al. 1989) 5 horses showed no significant worsening ventilation/blood (VA/Q) relationships during heavy exercise as determined by multiple inert gas elimination technique (MIGET). Because small number that and incidence induced VA/Q mismatch, we studied an additional 6 Thoroughbreds, comparing at walk (1.4 m/s, 0 degrees...
To determine a safe and efficacious dose of flecainide acetate for treating equine atrial fibrillation (Af), the dosage level was determined by injecting 1, 2, or 3 mg/kg i.v. 1% solution at rate 0.2 mg/kg/min to five clinically healthy horses. Clinical signs ECG were monitored (HR, PR, QRS, QT intervals) blood taken measure plasma concentration pre- post-administration. No abnormal observed in 1- 2-mg/kg groups, while agitation three horses 3-mg/kg group. The intervals group increased...
Summary A major factor contributing to the athletic ability of horse is exercise induced splenic contraction that augments both circulating blood volume (by about 12 litres) and haemoglobin concentration [Hb] a 1.5–2). We examined separately consequences 1) splenectomy 2) subsequent transfusion at lower post on pulmonary muscle O 2 transport haemodynamics, elucidate separate influences augmentation these processes. studied 6 Thoroughbreds (bwt 472 kg), (3 splenectomised, 3 controls)....
Alimentary lymphoma was evaluated endoscopically in 7 dogs and a histopathological examination made to detect the origin of neoplastic lymphocytes 5 dogs. A solitary mass rectum (1 case), irregular cobblestone appearance duodenum (4 cases) moderate resembling lymphocytic-plasmacytic enteritis (2 were detected. Endoscopic ultrasonography demonstrated increased thickness duodenal wall 2 cases examined. Neoplastic alimentary proved originate T cells all examined by immunohistochemical analysis.
After acclimatization to high altitude, maximal exercise cardiac output (Q˙t) is reduced. Possible contributing factors include 1) blood volume depletion, 2) increased viscosity, 3) myocardial hypoxia, 4) altered autonomic nervous system (ANS) function affecting heart rate (HR), and 5) reduced flow demand from muscle work capability. We tested the role of ANS reduction HR in this phenomenon five normal subjects by separately blocking sympathetic parasympathetic arms during after 2-wk at...
Brachycephalic airway syndrome (BAS) is a common disease in certain "flat-faced" dog breeds. This includes stenotic nares, elongated and thickened soft palate, laryngeal collapse, tracheal hypoplasia. Pharyngeal collapse also commonly observed, but it unclear if laryngopharynx motions are merely sequelae or actually contribute to BAS respiratory symptoms. Laryngopharynx motion was imaged using dynamic four-dimensional computed tomography (4D-CT) during spontaneous respiration four dogs with...
The manipulation mechanism of the giant panda ( Ailuropida melanoleuca ) was examined by means CT (computed tomography) and 3‐dimensional (3‐D) Volume Rendering techniques. In 3‐D images hand, not only bones but also muscular system visualised. Sections articulated skeleton were obtained. It demonstrated that hand is equipped with separately moulded units as follows: (1) radial sesamoid (RS), carpal, first metacarpal (R–R–M) complex; (2) accessory carpal (AC) ulnar (A–U) complex. When grasps...
The movement of the carpal bones in gripping was clarified giant panda (Ailuropoda melanoleuca) by means macroscopic anatomy, computed tomography (CT) and related 3-dimensional (3-D) volume rendering techniques. In action, 3-D CT images demonstrated that radial 4th largely rotate or flex to ulnar sides respectively. This indicates these on both enable palm from forearm grasp objects manipulation mechanism includes sesamoid. observations, we found smooth articulation surfaces are enlarged...
A castrated male border collie 23 months of age weighing 19.4 kg was referred to the Animal Medical Center Nihon University with complaints visual disturbance and behavioral abnormality, hyperacusis morbid fear. The MRI examination revealed slight dilated cerebral sulci cerebellar fissures left ventricular enlargement. This is first report findings canine neuronal ceroid lipofuscinosis.
Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing rise. In this study, we report first case feline sinonasal aspergillosis caused by fischeri in Japan. The patient presented after 2 months progressive facial deformity around nose and nasal discharge. isolate from was susceptible itraconazole (ITZ), voriconazole micafungin, but resistant amphotericine B. However, infected cat died approximately 1...
Herein, we investigated the positional relationship between cervical esophagus and trachea using computed tomography (CT) images in dogs with tracheal flattening. From these CT images, ratio of diameters short (vertical) long (horizontal) axes ring (S/L ratio) vertebra - (VTE) angle were measured at point from 3rd (C3) to thoracic (T3) levels. The VTE flattening an S/L under 0.24 tended be smaller than angles level C4 T2 over 0.25. seems possibly related cross-sectional shape.
The domestic horse (Equus caballus) have the large symmetrical guttural pouches (the auditory tube diverticulum) formed by saccate bulge of tube. In this study, CT examination was carried out in head Przewalski's przewalskii), only true wild living at present. As results examination, possessed divided into medial and lateral compartments stylohyoid bone. Moreover, right left meet each other median part to form a thin septum. sections get close occipital condyle, compartment disappeared,...
The present study used data from anesthetic records to analyze variables of intracranial pressure (ICP) during brain tumor surgery or in the early postoperative period as prognostic indicators dogs. Data 17 dogs which were scheduled undergo elective craniotomy for 2009 2012 included. Of these, five (29.4%) died 14 days after because respiratory failure following pneumonia (n=2), euthanasia due difficulty treatment status epilepticus (n=1), tumor-bed hematoma and unknown reason (n=1). In 12...
The atrioventricular (AV) conductive functions were investigated before and after the pharmacological autonomic nervous blockade (PAB) through electrophysiological study on six horses (AV block group) in which dropped beats occurred more frequently (over 200 beats/24 hr) five (control sporadically (under or arrhythmias not recognized at all long-term electrocardiogram. As a result, AV conductivity, conduction time refractoriness group lower, longer higher, respectively, than those control...
To evaluate the hemostatic effects of desmopressin (DDAVP) in dogs with aspirin-induced platelet dysfunction and impairment chronic liver diseases, 3 μg/kg DDAVP was administrated subcutaneously. In (n=5), prolonged BMBT (buccal mucosal bleeding time) shortened significantly after injection (2.2 ± 1.2 min, P<0.05). diseases (n=4), activated partial thromboplastin time (APTT) tended to shorten by 0.9 3.0 sec, two cases for 4.2 1.7 min injection. Therefore, present results indicated that...