A5101633795- Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Viral-associated cancers and disorders
- Ovarian cancer diagnosis and treatment
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
- Esophageal Cancer Research and Treatment
- Cancer and Skin Lesions
- CNS Lymphoma Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Brain Metastases and Treatment
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Cutaneous lymphoproliferative disorders research
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Chromatin Remodeling and Cancer
- Monoclonal and Polyclonal Antibodies Research
- Gastric Cancer Management and Outcomes
Shanxi Medical University
2013-2025
University of Notre Dame
2025
Xi'an Medical University
2025
Shanxi Provincial Cancer Hospital
2014-2024
Inner Mongolia Comprehensive Disease Prevention and Control Center
2023
Fudan University Shanghai Cancer Center
2021
Soochow University
2019
Shandong Provincial QianFoShan Hospital
2007
Patients with esophageal squamous cell carcinoma (ESCC) are commonly at high risk of recurrence within 2 y after initial treatment. The aim this study was to evaluate the role 18F-FDG PET/CT in patients possibly recurrent ESCC who underwent definitive treatment.Fifty-six previously treated scans. findings were validated by histopathology or clinical follow-up least 6 mo. sensitivity, specificity, and accuracy for detecting calculated. Comparison standardized uptake value (SUV) performed...
Background The study was conducted to investigate the clinicopathological features and prevalence of ROS1 gene fusion in Chinese patients with non‐small cell lung cancer (NSCLC). Methods presence assessed by quantitative real‐time PCR. Associations between clinical characteristics were analyzed. Results In total, 6066 pathologically confirmed NSCLC test results enrolled. average age 60.89 ± 10.60 years detected 157 (2.59%) patients. Fusion frequency significantly correlated age, gender,...
Abstract Alpha-fetoprotein-producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of cancer (GC). A comprehensive analysis clinicopathological features, immunophenotypes, molecular characteristics, survival in AFPGC contributes to identifying potential therapeutic targets developing new strategies manage this disease. retrospective cohort study was conducted at Shanxi Cancer Hospital from January 2018 December 2020, involving patients diagnosed with GC elevated AFP serum...
Ovarian cancer is the gynecological malignancy with highest mortality rate. Due to late detection and easy recurrence, 5-year survival rate of advanced ovarian patients less than 30%. The current standard treatment for includes platinum-based combination therapy. Most achieve clinical remission; however, short-term recurrence still high. For recurrent cancer, who are unwilling receive chemotherapy or cannot tolerate after multiple lines chemotherapy, "chemotherapy-free" may be appropriate....
Abstract Background This study aimed to investigate the prognostic impact of lymph node metastasis (LNM) on patients with colorectal cancer liver (CRLM) and elucidate underlying immune mechanisms using multiomics profiling. Methods We enrolled CRLM from US Surveillance, Epidemiology, End Results (SEER) cohort a multicenter Chinese cohort, integrating bulk RNA sequencing, single-cell sequencing proteomics data. The cancer-specific survival (CSS) profiles tumor-draining nodes (TDLNs), primary...
Pancreatic ductal adenocarcinoma (PDAC) is a aggressive and often lethal form of exocrine pancreatic cancer with 5-year survival rate 12%. Current PDAC therapeutics are ineffective highly toxic, leading to variety harsh side effects that greatly reduce patient quality life. This low life highlights the need for new approaches. study investigates potential inducing nuclear envelope instability in cells through inhibition Vaccinia-Related Kinase 1 (VRK1). Previous studies Vaughan lab have...
Malignant and premalignant ocular surface tumors (OSTs) can be sight-threatening or even life-threatening if not diagnosed treated promptly. Artificial intelligence holds great promise for the early detection of these diseases. However, training traditional convolutional neural networks (CNNs) this task presents challenges due to lack large, well-annotated datasets containing OST images labeled according histopathological results. Here, we introduce pretrained model (OSPM), a domain-specific...
// Bin Song 1,2,3,* , Heyang Cui 1,2,* Yaoping Li 1,4,* Caixia Cheng 1,2,5,* Yang Fang Wang Pengzhou Kong Hongyi 1,2 Ling Zhang Zhiwu Jia Yanghui Bi Jiaqian 6 Yong Zhou Jing Liu 1,7 Juan Zhenxiang Zhao Yanyan Xiaoling Hu Ruyi Shi Jie Haiyan 1,2,8 Ting Yan Yike Enwei Xu 1,2,9 Yu Qian Yanfeng Xi 9 Shiping Guo 4 Yunqing Chen Jinfen Guodong Jianfang Liang 5 Junmei 3 Xing 10 Jiansheng 7 Tong 11 Yanbo Qingshan 12 Chuangui 13 Xiaolong Qimin Zhan 14 and Yongping 1 Translational Medicine Research...
Brain metastasis (BM) is a poor prognostic factor for non-small-cell lung cancer (NSCLC). Recent studies have shown that oral epidermal growth receptor (EGFR) tyrosine kinase inhibitors (TKIs) were effective BM from NSCLC with EGFR mutation. However, the relationship between mutations and prognosis of patients remains to be determined. In this study, we investigated impact mutation status on survival NSCLC. One hundred six retrospectively reviewed. Thirty-three subjects (24.3 %) confirmed an...
// Hongwei Li 1, * , Jianhong Lian 2 Songyan Han 3, Weili Wang 1 Haixia Jia Jianzhong Cao Xiaqin Zhang Xin Song Sufang Jiwei Ren 5 Weihua Yang 3 Yanfeng Xi 4 and Shengmin Lan Department of Radiation Oncology, Shanxi Provincial Cancer Hospital, Medical University, Taiyuan, Province 030013, People's Republic China Surgery, Chemotherapy, Pathology, Imageology, These authors have contributed equally to this work Correspondence to: Li, email: 3420010@163.com Lian, 438129230@qq.com Keywords: lung...
Progression of disease within 24 months (POD24) is a risk factor for poor survival in follicular lymphoma (FL), and there currently no optimal prognostic model to accurately predict patients with early progression. How combine traditional models new indicators establish prediction system, the progression FL more future research direction.This study retrospectively analyzed newly diagnosed Shanxi Provincial Cancer Hospital from January 2015 December 2020. Data undergoing immunohistochemical...
The aim of this study is to evaluate the clinicopathological features and treatment Burkitt-like lymphoma with 11q aberration.We reported two patients aberration: a 56-year-old man AIDS (case 1) 37-year-old woman 2) without AIDS. biopsy cervical lymph nodes showed morphologic immunophenotypic features. But both them lack MYC rearrangement carry an 11q-arm aberration proximal gains and/or telomeric losses. diagnosis was confirmed by pathological morphology, immunohistochemistry, fluorescence...
e15500 Background: Colorectal signet ring cell carcinoma (CRC-SRC) is a malignant tumour characterized by its aggressive nature and unfavourable prognosis. In spite of the fact that numerous studies have examined molecular profile therapeutic targets CRC-SRC, prognostic biomarkers for this malignancy continue to be unknown. Methods: We conducted comprehensive analysis multi-omics in 35 cases CRC-SRC 10 colorectal adenocarcinomas (CRC-AC). This involved various techniques, including...
Lung cancer is the leading cause of cancer-related morbidity and mortality in People's Republic China. Targeted therapies for patients with lung cancer, which depend on accurate identification actionable genomic alteration, have improved survival compared previously available treatments. However, data types molecular testing often used China, how they changed over time, are scarce. We explored overall landscape mainland China past decade.
This study aims to understand the clinical features, treatment, and prognosis of patients with male breast cancer (MBC) in Shanxi province China from 2007 2016. Data for 77 MBC were collected analysis. Immunohistochemistry, pathological results, other data such as demographic characteristics (age, marital status, smoking history, drinking family history cancer) well investigated by retrieving information patients' medical records. A total 12,404 diagnosed between 2016, among them. The median...
Secretory carcinoma of the salivary gland (SCSG) is a recently discovered tumor that occurs mostly in major glands and occasionally skin, cervix, trachea, etc. lung extremely rare. To our knowledge, this third report SCSG arising as primary pulmonary tumor. The two cases reported paper are unique one was other metastasized to lung.Case 1 endobronchial 66-year-old man. He went doctor complaining fever, cough yellow phlegm, his body weight significantly reduced by 3 kg. bronchoscope showed...
To study the clinicopathologic features of combined hepatocellular-cholangiocarcinoma (cholangiolocellular type, CLC type) with stem cell and its relationship to hepatic progenitor cells (HPCs).Clinical histologic 26 cases (CLC were reviewed. Histochemistry was performed confirm type mucin immunohistochemical carried out for hepatocytic markers (Hep Par-1 AFP) biliary/HPCs (CK7, CK9, EMA, EpCAM, NCAM, CKIT).The age patients ranged from 51 82 years (mean 64 years). All contained...
Anaplastic carcinoma mural nodules in ovarian mucinous tumors are very rare. This study aimed to report the morphological characteristics, molecular detection results, clinical treatment and prognosis of three with anaplastic carcinoma.The pathomorphological features, were described cases. In case 1, sarcoma-like (SLMNs) coexisted nodules. No mutation was found tumors. KRAS heterotypic cells SLMNs. 2, occurred epithelium BRAF 3, both had same a transition between them observed. All patients...
e23528 Background: The rarity and heterogeneity of sarcoma has been complicating the diagnosis for years. Even expert pathologists could make mistakes in this disease. availability Next Generation Sequencing (NGS) data enabled more accurate sarcoma. In study, we systematically described application NGS on contribution to diagnostic accuracy Methods: A multi-center, retrospective study included 235 patients’ tumor paired normal samples that were sent from 56 hospitals a College American...