A5100786263- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Heme Oxygenase-1 and Carbon Monoxide
- Orthodontics and Dentofacial Orthopedics
- Acute Ischemic Stroke Management
- Inflammasome and immune disorders
- Climate Change and Health Impacts
- Immune cells in cancer
- Traumatic Brain Injury and Neurovascular Disturbances
- Kruppel-like factors research
- Digital Media and Visual Art
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumors and treatment
- Toxoplasma gondii Research Studies
- Meningioma and schwannoma management
- Advanced Glycation End Products research
- Eicosanoids and Hypertension Pharmacology
- Sepsis Diagnosis and Treatment
- dental development and anomalies
- Alzheimer's disease research and treatments
- Temporomandibular Joint Disorders
- Fibroblast Growth Factor Research
- Meta-analysis and systematic reviews
- Clinical Reasoning and Diagnostic Skills
- Neurosurgical Procedures and Complications
Wenzhou Medical University
2025
General Hospital of Shenyang Military Region
2024
Zhejiang Gongshang University
2024
Third People's Hospital of Hefei
2024
Anhui Medical University
2024
Xinqiao Hospital
2013-2020
Army Medical University
2010-2020
Guangdong Medical College
2016
Daping Hospital
2010-2012
Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-induced neurological deficits; however, the signaling pathways are not apparent by which upstream cellular events trigger innate immune and inflammatory responses that contribute to impairments. Toll-like receptor 4 (TLR4) damage caused brain disorders. In this study, we investigate of TLR4 ICH-induced inflammation. ICH model, significant upregulation expression reactive microglia has been demonstrated using...
Objective Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)‐induced secondary brain injury. However, the upstream events that initiate inflammatory responses following ICH remain elusive. Our previous studies suggested Toll‐like receptor 4 (TLR4) may be signal triggers ICH. In addition, recent clinical findings indicated both TLR2 and TLR4 participate ICH‐induced it is unclear how functions interacts with TLR4. Methods The of TLR2/TLR4 heterodimerization was...
High-mobility group protein box-1 (HMGB1) is a proinflammatory involved in many inflammatory diseases. However, its roles intracerebral hemorrhage (ICH) remain unknown. The purpose of this study was to examine the correlation between changes serum levels HMGB1 following acute ICH and severity stroke as well underlying mechanism. Changes 60 consecutive patients with primary hemispheric within 12 hours onset symptoms were determined. disease severity, IL-6, TNF-<mml:math...
ABSTRACT Background Different protocols exist regarding wear time of invisible aligners. There is no study that compared the effect different protocols. The aim this was to assess Invisalign aligners in four first‐premolar extraction treatments adolescents using three aligner protocols, every 7, 10 and 14 days. Materials Methods In experimental set‐up, 50 participants were divided into distinct groups: group A, with a regimen changing 7 days; B, 10‐day interval for replacement; C, where...
Toxoplasma gondii is an obligate intracellular parasite that stimulates production of high levels proinflammatory cytokines, which are important for innate immunity. NLRs, i.e., nucleotide-binding oligomerization domain (NOD)-like receptors, play a crucial role as immune sensors and form multiprotein complexes called inflammasomes, mediate caspase-1-dependent processing pro-IL-1β. To elucidate the inflammasome components in T. gondii-infected THP-1 macrophages, we examined...
Circulating factors associated with aging have been shown to be involved in the development of age-related chronic and acute brain diseases. Here, we aimed investigate roles mechanisms CCL12, a circulating factor that is highly expressed plasma aged rodents after intracerebral hemorrhage (ICH) using parabiosis ICH models. Neurological deficit score (NDS), mortality rate, water content (BWC), levels inflammatory were determined assess degree ICH-induced injury. Peripheral cell infiltration...
Neurofibromatosis type 1 (NF1) is a common inherited disorder characterized by cutaneous neurofibromas and other features. It still challenge in managing inoperable patients the complex nature of disease. Bibliometric analyses for (cNF) could offer insights into impactful research collaborations, guiding future efforts to improve patient care outcomes.
Abstract Introduction Excessive neuroinflammation aggravates the brain injury caused by intracerebral hemorrhage (ICH), while upstream mechanisms that initiate remain unclear. Toll‐like receptor 4 (TLR4) signaling is important to trigger inflammatory responses in ICH, and cold‐inducible RNA‐binding protein (CIRP) has been shown as a novel ligand of TLR4 recent studies. However, whether CIRP could via activating ICH still needs be investigated. Methods Human serum levels were measured using...
Abstract Aging has been shown to contribute both the declined biofunctions of aging brain and aggravation acute damage, former could be reversed by young plasma. These results suggest that plasma treatment may also reduce damage induced intracerebral hemorrhage (ICH). In present study, we first found administration significantly reduced mortality neurological deficit score in ICH rodents, which might due decreased water content, damaged neural cells, increased survival neurons around...
<title>Abstract</title> Background There is a surge in research on clear aligner treatment (CAT) with its growing appeal and controversy. This study presents bibliometric analysis visualization of CAT based the 100 most cited articles. Methods Time confined from January 1, 2000 to September 30, 2023, using Web Science Core Collection(WoS-CC), PubMed Embase database as data source, total articles highest citation frequency were retrieved, analyzed by bibliometrics help VOSviewer CiteSpace. A...