- Analytical Methods in Pharmaceuticals
- Carcinogens and Genotoxicity Assessment
- Effects and risks of endocrine disrupting chemicals
- Antibiotics Pharmacokinetics and Efficacy
- MicroRNA in disease regulation
- Membrane-based Ion Separation Techniques
- Membrane Separation Technologies
- Extraction and Separation Processes
- Pharmacogenetics and Drug Metabolism
- Plasma Applications and Diagnostics
- Organ and Tissue Transplantation Research
- Hormonal and reproductive studies
- Ferroptosis and cancer prognosis
- Fungal Biology and Applications
- Pharmaceutical studies and practices
- Cancer Treatment and Pharmacology
- Pain Management and Opioid Use
- Analytical Chemistry and Chromatography
- Heusler alloys: electronic and magnetic properties
- Plant Pathogens and Fungal Diseases
- Microbial Natural Products and Biosynthesis
- Paraquat toxicity studies and treatments
- Autoimmune and Inflammatory Disorders Research
- 2D Materials and Applications
- Organ Donation and Transplantation
Guangzhou Institute of Geochemistry
2025
Wenzhou Medical University
2010-2023
Obstetrics and Gynecology Hospital of Fudan University
2019
Zhejiang University of Technology
2015
Hohai University
2010
Dicyclohexyl phthalate (DCHP) is one of the plasticizers. The objective present study was to investigate effects DCHP on fetal Leydig cell distribution and function as well testis development. Female pregnant Sprague Dawley dams orally received vehicle (corn oil, control) or (10, 100, 500 mg/kg/day) from gestational day (GD) 12 GD 21. At 21.5, testicular testosterone production, number distribution, gene protein expression levels were examined. administration produced a dose-dependent...
Abstract A sensitive and selective liquid chromatography–tandem mass spectrometry method for the determination of pethidine in human plasma was developed validated over concentration range 4–2000 ng/mL. After addition ketamine as internal standard, liquid–liquid extraction used to produce a protein‐free extract. Chromatographic separation achieved on 100 × 2.1 mm, 5 µm particle, Allure TM PFP propyl column, with 45:40:15 (v/v/v) acetonitrile–methanol–water containing 0.2% formic acid mobile...
A sensitive and selective liquid chromatography tandem mass spectrometry (LC-MS-MS) method for determination of urapidil hydrochloride in rabbit plasma was developed validated. After addition doxapram as the internal standard (IS), protein precipitation by 10% trichloroacetic acid used sample preparation. Chromatographic separation achieved on a Zorbax SB-C18 (2.1 mm × 50 mm, 3.5 μm) column with acetonitrile-water mobile phase gradient elution. Electrospray ionization (ESI) source applied...
Multiple sequence magnetic resonance imaging (MRI) is often hampered by noise and misalignment. The wavelet de-noising lacks directivity does not preserve image details, which limits its effectiveness. To solve the problem, an adaptive threshold method based on transformation employed. As to misalignment, a registration basis of shape context descriptor proposed accurately align multiple MR sequences. In order achieve better MRI capabilities, new criteria that distribution in high low sub...