A5101948186- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Heme Oxygenase-1 and Carbon Monoxide
- Erythrocyte Function and Pathophysiology
- Hemoglobin structure and function
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Cardiac Ischemia and Reperfusion
- Plant-Microbe Interactions and Immunity
- Neonatal Health and Biochemistry
- High Altitude and Hypoxia
- Cardiac Fibrosis and Remodeling
- Coal and Its By-products
- Acute Kidney Injury Research
- Phytochemicals and Antioxidant Activities
- Climate Change and Health Impacts
- Powdery Mildew Fungal Diseases
- Recycling and utilization of industrial and municipal waste in materials production
- Marine and environmental studies
- Mesenchymal stem cell research
- NF-κB Signaling Pathways
- Blood properties and coagulation
- Plant Molecular Biology Research
- Geology and Paleoclimatology Research
- Bauxite Residue and Utilization
- Blood transfusion and management
Academy of Military Medical Sciences
2012-2018
China Agricultural University
2009-2017
Zero to Three
2015
Novem (Netherlands)
2015
Zhengzhou University
2014
Nanjing University
2010
In Arabidopsis (Arabidopsis thaliana) plants growing under normal conditions, DEHYDRATION-RESPONSIVE ELEMENT BINDING PROTEIN2A (DREB2A) is present at low levels because it ubiquitinated and destabilized by DREB2A INTERACTING PROTEIN1 (DRIP1) DRIP2 through 26S proteasome-mediated proteolysis. Drought stress counteracts the ubiquitination proteolysis of DREB2A, thus allowing accumulation sufficient amounts protein to activate downstream gene expression. The mechanisms leading drought...
Heme oxygenase-1 (HO-1) potently influences tumor growth and metastasis. To date, no study has been performed on HO-1 expression pattern its clinicopathological significance in human gastric cancer (GC) cases. In this study, the of GC tissues ( n = 74) matched non-tumoral adjacent parenchyma 46) was investigated by immunohistochemistry. The correlation with characteristics analyzed. Results showed that expressed 62 from 74 cases (83.8%), which is significantly higher than (20/46, 43.8%, P...
We previously showed that ethylene might be involved in the process of shikonin biosynthesis regulated by light signals. Here, we cloned a full-length cDNA LeERF-1, putative response factor gene, from Lithospermum erythrorhizon using RACE (rapid amplification ends) method. Phylogenetic analysis revealed LeERF-1 was classified B3 subfamily, together with ERF1 and ORA59 Arabidopsis. Heterologous expression Arabidopsis LeERF-1:eGFP fusion protein precisely localised to nucleus, implying it...
The optimal oxygen administration strategy during resuscitation from hemorrhagic shock (HS) is still controversial. Improving oxygenation and mitigating oxidative stress simultaneously seem to be contradictory goals. To maximize delivery while minimizing damage, the authors proposed notion of gradually increased (GIOA), which entails making arterial blood hypoxemic early in subsequently increasing hyperoxic, compared its effects with normoxic resuscitation, hyperoxic severe HS.Rats were...
Reactive oxygen species (ROS), which were largely generated after myocardial ischemia, severely impaired the adhesion and survival of transplanted stem cells. In this study, we aimed to determine whether Exendin-4 pretreatment could improve therapeutic efficacy adipose derived cells (ADSCs) in ischemic myocardium. vitro, H2O2 was used provide ROS environments, ADSCs pretreated with incubated. without as control. Then, cell viability analyzed time. Compared control ADSCs, treatment...
RBCs undergo numerous changes during storage and stored may induce adverse effects, ultimately resulting in organ injury transfusion recipients. We tested the hypothesis that addition of SP to would improve quality mitigate liver after a murine model. were harvested from C57BL/6J mice for 14 days CPDA-1 containing either solution saline or alone. Haemolysis, 24-hour posttransfusion recovery, oxygen-carrying capacity, SOD activity evaluated. The plasma biochemistry, hepatic MDA level, MPO...
Heme oxygenase-1 (HO-1) is often upregulated in tumour tissues and endows cells with cytoprotection antiapoptosis. It worthy of note that some people show higher activity HO-1 anti-cancer therapies could induce expression normal tissues, but the effect on tumours among these remains unknown. To assess progressiveness, we investigated growth, metastasis angiogenic potential murine melanoma B16F10 transgenic mice overexpressing its negative dominant mutant HO-1G143H, respectively. The results...
Plasma expanders are commonly used in the management of critically ill patients, which may exhibit altered hemorheology. We evaluated effects various synthetic colloids and Lactated Ringer's (LR) solution on hemorheological parameters vitro a rodent hemorrhagic shock model.For experiments, rat blood was incubated with hydroxyethyl starch (HES) 130/0.4, HES 200/0.5, succinylated gelatine (GEL), or LR at ratios. The control consisted without dilution. were measured after 15-min incubation. For...
Gradually increased oxygen administration (GIOA) seems promising in hemorrhagic shock. However, the effects of GIOA on survival remain unclear, and details are to be identified. After induction shock, rats were randomized into five groups (n = 9): normoxic group (Normo), hyperoxic (Hypero), (GIOA1), long-time hypoxemic (GIOA2), short-time (GIOA3). Survival was recorded for 96 h, plasma alanine transaminase, oxidative stress, hemodynamics, blood gas measured. The mean time GIOA3 significantly...
Abstract Heavy metals are important pollutants in the process of incineration solid waste and pose a potential threat to environment. In this paper, two heavy metals, Pb Cu, were taken as research objects, their migration rules furnace refuse, slag, fly ash flue gas tracked monitored respectively. The results showed that concentration ratios Cu slag 1:3.05 1:3.29, respectively, which consistent with waste. No was detected gas, but small amount present. XRF analysis shows CaO content is...
Introduction Linum usitatissimum seed or flax is known as a potential candidate remedy to treat various diseases in many traditional medicines around the world. In current study, antioxidant, cytotoxicity, and anti-human lung cancer properties of were investigated vitro conditions. Material methods Antioxidant activity plant was analyzed using radical scavenging ferrous ion chelating assay. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay used evaluate anti-lung...
摘要: