A5102711219- Pulmonary Hypertension Research and Treatments
- Religion, Spirituality, and Psychology
- Palliative Care and End-of-Life Issues
- Medical Imaging and Pathology Studies
- Bladder and Urothelial Cancer Treatments
- Pelvic floor disorders treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Grief, Bereavement, and Mental Health
- Colorectal Cancer Screening and Detection
- Systemic Sclerosis and Related Diseases
- Advanced Neuroimaging Techniques and Applications
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Vascular Anomalies and Treatments
- Sports injuries and prevention
- RNA modifications and cancer
- Protease and Inhibitor Mechanisms
- Advanced MRI Techniques and Applications
- Urinary Tract Infections Management
Children's Medical Center
2024
University of Cincinnati
2024
Cincinnati Children's Hospital Medical Center
2019-2024
Stetson University
2022
Hitit Üniversitesi
2022
University of San Francisco
2017
DKFZ-ZMBH Alliance
2009
German Cancer Research Center
2009
Rationale: Pulmonary arterial hypertension (PAH) is characterized by structural remodeling of pulmonary arteries and arterioles. Underlying biological processes are likely reflected in a perturbation circulating proteins. Objectives: To quantify analyze the plasma proteome patients with PAH using inherited genetic variation to inform on underlying molecular drivers. Methods: An aptamer-based assay was used measure proteins 357 idiopathic or heritable PAH, 103 healthy volunteers, 23 relatives...
Abstract Background Approximately 25% of patients with pulmonary arterial hypertension (PAH) have been found to harbor rare mutations in disease-causing genes. To identify missing heritability PAH we integrated deep phenotyping whole-genome sequencing data using Bayesian statistics. Methods We analyzed 13,037 participants enrolled the NIHR BioResource - Rare Diseases (NBR) study, which 1,148 were recruited domain. test for genetic associations between genes and selected phenotypes (PH), used...
Ziele: Detection of white matter hyperintensities (WMH) by using visual rating scales or manual volumetric measurement is problematic, because both methods rely heavily on the human eye and are hampered floor ceiling effects to detect changes in cerebral matter. Especially describe WMH a qualitative semi-quantitative way. Hence, intra- interrater reliability usually modest low as previous studies have shown. Our first purpose was evaluate clinical acceptability new fully automated method...