A5081133327- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Lanthanide and Transition Metal Complexes
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Medical Imaging Techniques and Applications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Neurological Disease Mechanisms and Treatments
- Schizophrenia research and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Ultrasound and Hyperthermia Applications
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Renal and Vascular Pathologies
- Endometrial and Cervical Cancer Treatments
- Cardiac Imaging and Diagnostics
- Memory and Neural Mechanisms
Health Sciences Centre
2015-2025
University of Manitoba
2014-2024
Ferioli & Gianotti (Italy)
2024
German Cancer Research Center
2008-2020
Heidelberg University
2007-2020
Institut d'Investigació Biomèdica de Girona
2020
Institut Universitari d'Investigació en Atenció Primària Jordi Gol
2020
Manitoba Harm Reduction Network
2016-2020
Friedrich-Alexander-Universität Erlangen-Nürnberg
2009-2019
Pan Am Clinic
2016-2018
Perfusion MRI: The Five Most Frequently Asked Technical QuestionsMarco Essig1, Mark S. Shiroishi2, Thanh Binh Nguyen3, Marc Saake1, James M. Provenzale4 5, David Enterline4, Nicoletta Anzalone6, Arnd Dörfler1, Àlex Rovira7, Max Wintermark8 and Meng Law2Audio Available | Share
Background The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is an established 10-point quantitative topographic computed tomography scan score to assess early ischemic changes. We performed a non-inferiority trial between the e-ASPECTS software and neuroradiologists in scoring ASPECTS on non-contrast enhanced images of acute stroke patients. Methods In this multicenter study, three independent retrospectively blindly assessed baseline 132 patients with anterior...
Laser Ablation After Stereotactic Radiosurgery (LAASR) is a multicenter prospective study of laser interstitial thermal (LITT) ablation in patients with radiographic progression after stereotactic radiosurgery for brain metastases.
To assess the value of spectroscopic and perfusion MRI for glioma grading distinguishing glioblastomas from metastases CNS lymphomas.The authors examined 79 consecutive patients with first detection a brain neoplasm on nonenhanced CT scans no therapy prior to evaluation. Spectroscopic MRI; arterial spin-labeling measuring cerebral blood flow (CBF); first-pass dynamic, susceptibility-weighted, contrast-enhanced volume; T1-weighted dynamic were performed. Receiver operating characteristic...
Malignant gliomas remain incurable brain tumors because of their diffuse-invasive growth. So far, the genetic and molecular events underlying gliomagenesis are poorly understood. In this study, we have identified receptor tyrosine kinase Axl as a mediator glioma growth invasion. We demonstrate that its ligand Gas6 overexpressed in human cell lines is activated under baseline conditions. Furthermore, expressed at high levels malignant glioma. Inhibition signaling by overexpression...
Objectives To determine whether a specific, standardized training regimen can improve muscle strength and physical functioning in people with dementia. Design Double‐blinded, randomized, controlled trial 3‐month intervention follow‐up period 2006 to 2009. Setting Outpatient geriatric rehabilitation. Participants Individuals confirmed mild moderate dementia, no severe somatic or psychological disease, ability walk 10 m. Most participants were still living independently without supportive...
Abstract 23 Na MRI has the potential to noninvasively detect sodium (Na) content changes in vivo. The goal of this study was implement a clinical setting for neurooncological and muscular imaging. Due biexponential T 2 decay tissue signal with short component, which ranges between 0.5–8 ms, measurement total requires imaging techniques echo times (TEs) below 0.5 ms. A 3D radial pulse sequence TE 0.2 ms at spatial resolution 4 × mm 3 developed that allows acquisition presentation images on...
Background One of the core symptoms borderline personality disorder (BPD) is instability in interpersonal relationships. This might be related to existent differences mindreading between BPD patients and healthy individuals. Methods We examined behavioural neurophysiological (fMRI) responses controls (HC) during performance 'Reading Mind Eyes' test (RMET). Results Mental state discrimination was significantly better faster for affective eye gazes than HC. At level, this manifested a stronger...
This is the second part of series on interventional ultrasound guidelines Federation Societies for Ultrasound in Medicine and Biology (EFSUMB). It deals with diagnostic procedure. General points are discussed which pertinent to all patients, followed by organ-specific imaging that will allow correct pathway planning appropriate workup each individual procedure (Long version).
Although it is well established that cerebral activation increases with higher task load, the potential effects of training have been investigated over brief periods only. Training clinical relevance since programs are an essential part psychiatric therapy.Cerebral during a visual spatial working memory was examined before, during, and after 4 weeks daily in nine healthy subjects using functional magnetic resonance imaging.All showed pronounced mainly involving right inferior frontal gyrus...
To compare two different three-dimensional (3D) gadolinium-enhanced magnetic resonance (MR) angiographic techniques.In 26 patients suspected of having renal artery stenosis, results with fast multiphase 3D MR angiography were compared to those standard in 37 patients. With both techniques, 31-second breath-hold acquisitions performed. Multiphase comprised five discrete 6.4-second without bolus timing, and a single acquisition based on test-bolus timing. Two readers evaluated images obtained...
To analyze the blood flow dynamics in renal artery stenosis with high-temporal-resolution cine phase-contrast magnetic resonance (MR) measurements.Cine MR measurements were invasively validated real-time intraoperative transit-time ultrasound (US). In 23 patients, 48 stenoses confirmed at digital subtraction angiography. Cardiac-gated obtained 32-msec intervals, and curves calculated for whole cardiac cycle. Hemodynamic parameters evaluated included decrease mean delay reduction systolic...
Exogenous magnetic resonance (MR) contrast media (CM) are used to improve detection and delineation of physiological pathologic structures. Temporary binding between CM proteins such as human serum albumin (HSA) may alter the relaxation-enhancing properties specific agents. In this study, presence strength HSA interaction with different was investigated.Three agents were chosen: Gd-DTPA, Gd-BT-DO3A, Gd-BOPTA, each which is known have a protein interaction. Samples prepared using 7...