- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Prostate Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Cancer Genomics and Diagnostics
- Amoebic Infections and Treatments
- Shape Memory Alloy Transformations
- Gastric Cancer Management and Outcomes
- Welding Techniques and Residual Stresses
- Pediatric Urology and Nephrology Studies
- Immunotherapy and Immune Responses
- Abdominal Trauma and Injuries
- Ureteral procedures and complications
- Kidney Stones and Urolithiasis Treatments
- Microstructure and mechanical properties
- Pelvic floor disorders treatments
- Topology Optimization in Engineering
- Prostate Cancer Treatment and Research
- MRI in cancer diagnosis
- Clinical Nutrition and Gastroenterology
Herlev Hospital
2014-2025
Copenhagen University Hospital
2007-2025
Gentofte Hospital
2021-2024
University of Copenhagen
1997-2023
University Gastroenterology
2023
Baylor College of Medicine
2018
Texas Children's Hospital
2018
University of Alabama
2018
Thomas Jefferson University
2018
Division of Undergraduate Education
2018
Ultrasound (US)-guided interstitial hyperthermia performed with the neodymium yttrium aluminum garnet laser a diffuser tip involves placement of fiber in solid tissue followed by irradiation from within center tumor to be treated. The authors previously described development US-guided technique that permits simultaneous and temperature measurements, real-time US monitoring. With use dedicated modification bare fiber, it has proved possible produce spherical coagulations diameter comparable...
Objectives To achieve international consensus across multiple specialties on a generic ultrasound rating scale using Delphi technique. Methods Ultrasound experts from Obstetrics-Gynaecology, Surgery, Urology, Radiology, Rheumatology, Emergency Medicine, and Gastro-Enterology representing North America, Australia, Europe were identified. A multi-round survey was conducted to obtain between these experts. Of 60 invited experts, 44 agreed participate in the first round, 41 remained second 37...
The third part of the European Federation Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines on Interventional assesses evidence ultrasound-guided assisted interventions abdominal treatment procedures. Recommendations clinical practice are presented covering indications, contraindications, safety efficacy broad variety these techniques. In particular, drainage abscesses fluid collections, interventional tumor ablation techniques, symptomatic cysts echinococcosis,...
The fourth part of the European Federation Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines on Interventional describes general aspects endoscopic ultrasound-guided diagnostic therapeutic interventions assesses evidence sampling. Endoscopic ultrasound combines most advanced high-resolution imaging lesions within wall vicinity gastrointestinal tract safe effective fine needle based tissue acquisition from these lesions. guideline addresses indications, contraindications,...
This is the second part of series on interventional ultrasound guidelines Federation Societies for Ultrasound in Medicine and Biology (EFSUMB). It deals with diagnostic procedure. General points are discussed which pertinent to all patients, followed by organ-specific imaging that will allow correct pathway planning appropriate workup each individual procedure (Long version).
To evaluate the clinical benefit of nivolumab with or without ipilimumab in combination stereotactic body radiotherapy (SBRT) patients refractory metastatic pancreatic cancer (mPC).Between November 2016 and December 2019, mPC were randomly assigned 1:1 to SBRT 15 Gy nivolumab/ipilimumab stratified by performance status (ClinicalTrials.gov identifier: NCT02866383). The primary end point was rate (CBR), defined as percentage complete partial response (PR) stable disease, according RECIST 1.1....
This is the first part of Guidelines on Interventional Ultrasound European Federation Societies for in Medicine and Biology (EFSUMB) covers all general aspects ultrasound-guided procedures (short version; long version published online).
The third part of the European Federation Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines on Interventional (INVUS) assesses evidence ultrasound-guided assisted interventions abdominal treatment procedures. Recommendations clinical practice are presented covering indications, contraindications, safe effective performance broad variety these techniques. In particular, drainage abscesses fluid collections, interventional tumor ablation techniques, symptomatic cysts...
The fifth section of the Guidelines on Interventional Ultrasound (INVUS) European Federation Societies for in Medicine and Biology (EFSUMB) assesses evidence all categories endoscopic ultrasound-guided treatment reported to date. Celiac plexus neurolysis block, vascular intervention, drainage fluid collections, biliary pancreatic ducts, experimental tumor ablation techniques are discussed. For each topic, current has been extensively analyzed summarized into major recommendations reader...
The fourth part of the European Federation Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines on Interventional describes general aspects endoscopic ultrasound-guided diagnostic therapeutic interventions assesses evidence sampling. Endoscopic ultrasound combines most advanced high-resolution imaging lesions within wall vicinity gastrointestinal tract safe effective fine needle-based tissue acquisition from these lesions. guideline addresses indications, contraindications,...
Background Neoantigens can serve as targets for T cell-mediated antitumor immunity via personalized neopeptide vaccines. Interim data from our clinical study NCT03715985 showed that the peptide-based neoantigen vaccine EVX-01, formulated in liposomal adjuvant, CAF09b, was safe and able to elicit EVX-01-specific cell responses patients with metastatic melanoma. Here, we present results dose-escalation part of study, evaluating feasibility, safety, efficacy, immunogenicity EVX-01 addition...
Therapeutic dendritic cell (DC) vaccination against cancer is a strategy aimed at activating the immune system to recognize and destroy tumor cells. In this nonrandomized phase 1/2 trial, we investigated safety, feasibility, induction of T-cell response, clinical response after treatment with DC-based vaccine in patients metastatic renal carcinoma. Twenty-seven progressive cytokine-refractory carcinoma were vaccinated DCs loaded either cocktail survivin telomerase peptides or lysate...
The fifth section of the Guidelines on Interventional Ultrasound (INVUS) European Federation Societies for in Medicine and Biology (EFSUMB) assesses evidence all categories endoscopic ultrasound-guided treatment reported to date. Celiac plexus neurolysis block, vascular intervention, drainage fluid collections, biliary pancreatic ducts, experimental tumor ablation techniques are discussed. For each topic, current has been extensively analyzed summarized into major recommendations reader...
Twelve subjects without and ten with diving experience performed short diving-related interventions. After labeling of erythrocytes, scintigraphic measurements were continuously during these All interventions elicited a graduated reproducible splenic contraction, depending on the type, severity, duration The contraction varied between ∼10% for “apnea” (breath holding 30 s) “cold clothes” (cold wet clothes applied face no breath ∼30–40% “simulated diving” (simulated breath-hold s), “maximal...
The aim of our study was to evaluate the efficacy microwave (MW) ablation liver metastases guided by B-mode ultrasound (US) and contrast-enhanced US (CEUS).39 patients (17 women 22 men) with a total 125 were treated percutaneous or intraoperative CEUS-guided MW ablation. primary tumor colorectal cancer (n = 31), breast 6), carcinoid 1), gastrointestinal stromal (GIST) 1). median number ablated in 45 treatment sessions 2 (range 1 - 11). size (maximum diameter) 1.5 cm (range, 0.6 4.0 cm)....
This is the first part of Guidelines on Interventional Ultrasound European Federation Societies for in Medicine and Biology (EFSUMB) covers all general aspects ultrasound-guided procedures (long version).