A5060482332- Tuberculosis Research and Epidemiology
- Selenium in Biological Systems
- Adipokines, Inflammation, and Metabolic Diseases
- Species Distribution and Climate Change
- Drug-Induced Hepatotoxicity and Protection
- Regulation of Appetite and Obesity
- Microbial bioremediation and biosurfactants
- Plant and animal studies
- Hepatitis B Virus Studies
- Photodynamic Therapy Research Studies
- Chronic Lymphocytic Leukemia Research
- Mycobacterium research and diagnosis
- Nanoplatforms for cancer theranostics
- Immunotherapy and Immune Responses
- Insect and Arachnid Ecology and Behavior
- Cytokine Signaling Pathways and Interactions
- Adipose Tissue and Metabolism
- Epigenetics and DNA Methylation
- Biochemical and biochemical processes
- Pesticide Residue Analysis and Safety
- Advanced Mathematical Theories and Applications
- Gout, Hyperuricemia, Uric Acid
- Social and Behavioral Studies
- Allelopathy and phytotoxic interactions
- Electrokinetic Soil Remediation Techniques
Ain Shams University
2013-2025
King Saud University
2021
Metallothionein (MT) is a low molecular mass protein inducible by heavy metals such as cadmium (Cd), zinc, and copper, having high affinity for these metals. In the present study, we investigated immunohistological localization of MT in brains rats mice. adult rat brain, almost no immunostaining was observed, whereas mouse brain strong found ependymal cells, some glial arachnoid, pia mater. No detected neurons endothelial cells. younger (1-3 weeks old), observed choroid plexus epithelium,...
Abstract Background Variants in the bone morphogenetic protein 2 receptor gene ( BMPR2 ) are most frequent genetic cause of pulmonary arterial hypertension (PAH). However, correlation variants and PAH clinical phenotype remains to be elucidated. Methods results The goal present study is investigate causative 25 Egyptian patients clinically pre-diagnosed with symptoms 10 healthy candidates using Sanger sequencing technique. Three pathogenic heterozygous missense have been illustrated gene,...
There is a need for an improved vaccine tuberculosis. ESAT-6 cardinal antigen with unique properties and included in several candidates development. also the core IFN-γ release assays (IGRA) used to diagnose latent infection, rendering IGRA tests unspecific after vaccination. This challenge has prompted development of companion diagnostic based vaccines, free IGRA. We screened panel seven potential new antigens not recognized BCG vaccinated individuals. Three highly EspC, EspF Rv2348c were...
Penitrem A (PA) is a food mycotoxin produced by several terrestrial and few marine Penicillium species. PA potent tremorgen through selective antagonism of the calcium-dependent potassium BK (Maxi-K) channels. Discovery natural products that can prevent toxic effects important for safety. Astaxanthin (AST) xanthophyll carotenoid with documented antioxidant activity. Unlike other common antioxidants, AST cross blood brain barriers (BBBs), inducing neuroprotective effects. Docosahexaenoic acid...
Mesenchymal stem cells have therapeutic properties that are related to their potentials for trans-differentiation, immunomodulation, anti-inflammatory, inhibitory effect on tumor proliferation, and induction of apoptosis. This study was performed analyze the role mesenchymal as an alternative cellular signaling growth factors involved in pathogenesis leukemogenesis rats. Treatment rats with 7,12-dimethyl benz [a] anthracene induced appeared a significant decrease hematological parameters...
Background : The development of nanotechnology has been a boon to mankind as its significance paved the way for several applicaons in therapeucs. This study was evaluate an�-arthric capability nano Sel enium-lovastan mixture (Lov-Se) against inflammatory cascade arthric irradiated rats. Materials and Methods Animal model Arthris organized by subcutaneous injecon Complete Freund's adjuvant; CFA. Rats were exposed γ-radiaon (2Gy every 3 days up total dose 8 Gy). Lov-Se (1ml ≈ 20 mg kg −1 day...
This study, was established five groups of albino rats to determine the therapeutic effect Curcuma longa and ursofalk against toxicity CC14 in liver kidney. Group (1) received orally NaCl 0.9% used as a normal group. (2) injected intraperitoneal (i.p.) with CCl4 (1 ml/kg), 3 times weekly, for 2 weeks. (3) given Ursofalk (100 mg/kg per body weight), group (4) weight) (5) same doses plus 30 days respectively, post-injected ml/kg) Two blood samples were collected, hematological biochemical...
Abstract Objectives The aim of the current study was to assess natural course partial remission (PR) phase type 1 diabetes (T1D) and highlight putative association between vitamin D receptor (VDR) (Fok1) gene polymorphism PR phase. Methods Ninety participants with newly diagnosed T1D were followed up for a total 12 months. VDR rs2228570 genotyped using allelic discrimination (AD) assay. Results Fifty-four patients (60 %) reached an average duration 5.63 ± 2.9 Among remitters, frequency CC...
Toll-like receptors (TLRs) represent the immune link between innate and adaptive signals against various pathogens. This study aimed to evaluate TLRs3 7 as immune-markers in differentiating hepatitis C virus (HCV)-infected -uninfected patients. Also, use of TLR3 TLR7 markers was compared with prevalent bio for autoimmune diseases HCV-infected or The levels GPT, GOT, B cell activated factors, tumor necrosis factor-alpha (TNF-α), interleukin (IL)-10 were measured plasma, while quantified...
Background: Acute myeloid leukemia (AML) is characterized by clonal expansion of precursors with diminished capacity for differentiation. It develops as the consequence a series genetic changes in hematopoietic precursor cell. Purpose This study aimed to investigate correlation between GM-CSF gene expression and different molecular prognostic markers such FLT3-ITD, NPM1 mutation A CEBPA 100 Egyptian AML patients. As well as, response induction therapy, DFS andOS these Methodology:...