A5102968861- Identification and Quantification in Food
- Genetic diversity and population structure
- Analytical Chemistry and Sensors
- Analytical chemistry methods development
- Genomics and Phylogenetic Studies
- Drug Transport and Resistance Mechanisms
- Actinomycetales infections and treatment
- Mass Spectrometry Techniques and Applications
- Vector-Borne Animal Diseases
- Neuroscience and Neuropharmacology Research
- Crystal structures of chemical compounds
- Infectious Diseases and Mycology
- Mycobacterium research and diagnosis
- Face Recognition and Perception
- Infrared Thermography in Medicine
- Evolutionary Psychology and Human Behavior
- Writing and Handwriting Education
- Face recognition and analysis
- Neurological Disease Mechanisms and Treatments
- Lipid Membrane Structure and Behavior
- Bacterial biofilms and quorum sensing
- Neuroinflammation and Neurodegeneration Mechanisms
- Animal Virus Infections Studies
- Listeria monocytogenes in Food Safety
- Autophagy in Disease and Therapy
Second Hospital of Shandong University
2019-2024
Zhengzhou University
2024
Chengdu Research Base of Giant Panda Breeding
2017-2022
University of Otago
2014-2020
Northwest Normal University
2019-2020
Central China Normal University
2011
The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become potential threat to the health of these endangered animals, but limited information related available. Using viral metagenomic approach, we surveyed viruses feces, nasopharyngeal secretions, blood, and different tissues from that died an unknown disease, healthy panda, 46 captive animals. previously uncharacterized complete or near genomes four three genera...
Silicosis is an occupational disease caused by inhalation of silica and there are no effective drugs to treat this disease. Tanshinone IIA (Tan IIA), a traditional natural component, has been reported possess anti-inflammatory, antioxidant, anti-fibrotic properties. The current study's purpose was examine Tan IIA's protective effects against silica-induced pulmonary fibrosis explore the underlying mechanisms.48 male SD rats were randomly divided into four groups (n=12): i) Control group; ii)...
Glioma is the most prevailing main malignant neoplasm of central nervous system with a miserable prognosis. Temozolomide first-line chemotherapy drug for glioma, but its resistance reduces temozolomide's clinical efficacy and becomes principal cause failure glioma chemotherapy. Polyphyllin I (PPI), an active component in Rhizoma Paridis, demonstrates favorable therapeutic actions diverse neoplasms. Its effect on temozolomide-resistant however, has not yet been characterized. Here, we...
Previous studies have shown that giant pandas (Ailuropoda melanoleuca) can discriminate face-like shapes, but little is known about their cognitive ability with respect to the emotional expressions of humans. We tested whether adult from pictures half a face and found learn between angry happy based on global information whole face. Young (5-7 years old) learned more quickly than older individuals (8-16 old), no significant differences were females males. These results suggest young are...
Tick infestations have been reported as one of the factors threatening health giant pandas, but studies viral pathogens carried by ticks feeding on blood pandas are limited. To assess whether blood-sucking can carry and if so, viruses in associated with those previously detected panda hosts, we determined viromes detached from a field stocking area Sichuan Province, southwest China. Using metagenomics identified 32 species ticks, half which (including anellovirus [n = 9], circovirus 3],...
Research has suggested that exposure to sub-micellar concentrations of bile salts (BS) increases the permeability lipid bilayers in a time-dependent manner. In this study, incubation soy phosphatidylcholine small unilamellar vesicles (liposomes) with cholate (C), deoxycholate (DC), 12-monoketocholate (MKC) or taurocholate (TC) pH 7.2 buffer increased membrane fluidity and negative zeta potential order increasing BS liposome-pH distribution coefficients (MKC < C ≈ TC DC). liposomes labeled...
Large-scale molecular phylogenetic studies of the avian order Strigiformes have been performed, and numerous mitochondrial genomes determined. However, their intergeneric relationships are still controversial, few comprehensive comparative analyses conducted on Strigiformes. In this study, genome Otus lettia was determined compared with other The O. 16,951 bp in size. For Strigiformes, atp8 can be used as a suitable marker for population genetic diversity, while cox1 is candidate barcoding...
Abstract Background The effectiveness of flipped classroom (FC) on puncture skills in medical education is still uncertain. This study aimed to assess the role FC model and investigate acceptance approval among students instructors. Methods A mixed research approach quasi-experimental design descriptive qualitative was conducted September 2022 for one month, using an teaching method that combined instructional videos group learning. participants were 71 fifth-year from two classes at a...
<title>Abstract</title> <bold>Background</bold>Nocardia otitidiscaviarum is a relatively rare pathogen that belongs to the distinctive species within Nocardia genus. It typically found in soil or decaying matter and can enter body through break skin or, less commonly, respiratory tract. Pneumonic nocardial disease an uncommon infection primarily affects immunocompromised individuals. <bold>Case presentation</bold>This article presents case study of pneumonic nocardiosis 22-year-old...
Coxsackievirus (CV) A6 has emerged as an important causative agent in global outbreaks of hand, foot, and mouth disease (HFMD), which typically presents a mild illness with large generalized rash, herpes. However, some patients can develop encephalitis, pneumonia, myocarditis liver injury. Our previous study took the view that CVA6 could replicate mouse liver, leading to acute injury; however, precise underlying mechanism remains elusive. 10-day-old wild-type (WT, C57BL/6J) NLRP3 knock-out...
Abstract Objectives Ketotifen (K) and its active metabolite norketotifen (N) exist as optically atropisomers. They both have antihistaminic anti-inflammatory properties but the S-atropisomer of N (SN) causes less sedation than K RN in rodents. This study investigated whether this could be related to a lower concentration SN brain or affinity for rat H1 receptors. Methods atropisomers were quantified using validated chiral HPLC assay. RBE4 Caco-2 cell monolayers used uptake permeability...