A5031361426- Neuroscience and Neuropharmacology Research
- SARS-CoV-2 and COVID-19 Research
- Neurotransmitter Receptor Influence on Behavior
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Tryptophan and brain disorders
- Psychedelics and Drug Studies
- Genetics and Neurodevelopmental Disorders
- Cannabis and Cannabinoid Research
- Treatment of Major Depression
- Stress Responses and Cortisol
- Sleep and Wakefulness Research
- Nicotinic Acetylcholine Receptors Study
- Biochemical Analysis and Sensing Techniques
- Nuclear Receptors and Signaling
- Meta-analysis and systematic reviews
- Neuropeptides and Animal Physiology
- Memory and Neural Mechanisms
- Forensic Toxicology and Drug Analysis
- Bipolar Disorder and Treatment
- Adenosine and Purinergic Signaling
Universidade Federal de Santa Catarina
2019-2025
Abstract Background and Purpose Ayahuasca (AYA) is a botanical psychedelic with promising results in observational small clinical trials for depression, trauma drug use disorders. Its psychoactive effects primarily stem from N , ‐dimethyltryptamine (DMT). However, there lack of research on how where AYA acts the brain. This study addressed these questions by examining extinction aversive memories AYA‐treated rats. Experimental Approach We focused 5‐HT 1A 2A receptors, as DMT exhibits high...
Coronavirus disease 2019 (COVID-19) is a respiratory infection caused by severe acute syndrome coronavirus 2 (SARS-CoV-2) and marked an intense inflammatory response immune dysregulation in the most cases. In order to better clarify relationship between peripheral system changes severity of COVID-19, this study aimed evaluate frequencies absolute numbers subsets neutrophils, monocytes, dendritic cells (DCs), addition quantifying levels mediators. One hundred fifty-seven COVID-19 patients...
Concerns over the replicability and reproducibility of published research have grown in many fields, but empirical data to inform policies are still scarce. Biomedical Brazil expanded rapidly last three decades, with no systematic assessment its findings. With this mind, we set up Brazilian Reproducibility Initiative, a multicenter replication experiments from science using common experimental methods: MTT assay, reverse transcription polymerase chain reaction (RT-PCR) elevated plus maze...
Abstract Coronavirus disease 2019 (COVID‐19) is a respiratory tract infection caused by the new severe acute syndrome coronavirus 2 (SARS‐CoV‐2). An adequate T cell response essential not only for fighting but also creation of immune memory. Thus, present study aims to evaluate cells patients with moderate, and critical COVID‐19 at time illness months after diagnosis observe whether changes in this compartment persist. In study, 166 were stratified into moderate/severe categories. The...
Abstract Background In view of the scientific gap in knowledge involvement B-cell compartment and clinical prognostic SARS-CoV-2 infection, this work aims to evaluate subsets presence specific IgM IgG, as well neutralizing antibodies against SARS-CoV-2, unvaccinated patients diagnosed with COVID-19. Methods This study included 133 Cellular components were assessed by flow cytometry, immunoglobulin levels reactivity measured indirect enzyme-linked immunosorbent assay. Results Our results...