A5046469412- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Pharmaceutical and Antibiotic Environmental Impacts
- Infections and bacterial resistance
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Ocular Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Fungal Infections and Studies
- SARS-CoV-2 detection and testing
- Nail Diseases and Treatments
- Neutropenia and Cancer Infections
Sungkyunkwan University
2023-2024
Samsung Medical Center
2023-2024
Diminished immune response to coronavirus disease 2019 (COVID-19) vaccines and breakthrough infection (BI) is a major concern for solid organ transplant recipients. Humoral cellular responses of kidney (KT) recipients after third COVID-19 vaccination were investigated compared matched health care workers. Anti-severe acute respiratory syndrome 2 spike protein antibody severe specific interferon-gamma releasing assay (IGRA) assessed. A total 38 KT recipients, including 20 BI 18 noninfection,...
With the introduction of ceftazidime-avibactam worldwide, antimicrobial activity new β-lactam/β-lactamase inhibitors (BL/BLIs) needs to be investigated. From January 2020 June 2023, Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacterales were collected. a broth microdilution test BL/BLIs, cross-activity with nine combinations BLs and BLIs dose-escalation titration for non-susceptible isolates conducted investigate inhibitory activities BLIs. A total 188 was collected most...
Tixagevimab/cilgavimab is a monoclonal antibody used to prevent coronavirus disease 2019 among immunocompromised hosts and maintained neutralizing activity against early omicron variants. Omicron BN.1 became dominant circulating strain in Korea 2023, but its susceptibility tixagevimab/cilgavimab unclear. We conducted plaque reduction neutralization test (PRNT) prospective cohort (14 patients 30 specimens). PRNT was for one- three-months after administration the average ND50 of each point...
ABSTRACT In October 2022, we experienced a significant increase in samples showing high galactomannan (GM) indexes ranging from 6.22 to 10.58, as determined by the Platelia Aspergillus antigen immunoassay, also known GM test. After reviewing medical records of nine antigenemia cases that did not show evidence invasive aspergillosis, found these patients had received total parenteral nutrition (TPN) products same manufacturer, whose supplier glucose component recently changed. The TPN...
We present a case of disseminated aspergillosis diagnosed by choroid plexus biopsy in an immunocompeten 69-year-old male with decreased consciousness and fever for more than three months. Brain magnetic resonance imaging showed ventriculitis phlegmon the paravertebral space. Chest computerized tomography revealed air-crescent lesion upper lobe left lung. No microorganism was identified from blood or CSF cultures. A performed pathology findings were consistent fungal abscess caused invasive...
Abstract Background Piperacillin/tazobactam (PTZ) and cefepime (CFP) are commonly used antibiotics for healthcare-associated infections immunocompromised patients. However, few studies have compared the clinical effectiveness of these two antibiotics. Thus, we empirical PTZ CFP in patients with monomicrobial blood-stream infection (BSI) caused by gram-negative bacilli. Methods We conducted a retrospective cohort study consecutive, non-duplicate BSIs 1 4 taxa (Escherichia coli, Klebsiella...