- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Diverticular Disease and Complications
- Medical Image Segmentation Techniques
- Radiation Dose and Imaging
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- AI in cancer detection
- Metastasis and carcinoma case studies
- Urologic and reproductive health conditions
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Renal cell carcinoma treatment
- Advanced MRI Techniques and Applications
- Radiology practices and education
- Adipose Tissue and Metabolism
- Venous Thromboembolism Diagnosis and Management
- Advanced X-ray and CT Imaging
- Prostate Cancer Diagnosis and Treatment
Harvard University
2019-2023
University Hospital of Zurich
2017-2023
Brigham and Women's Hospital
2022-2023
Beth Israel Deaconess Medical Center
2019-2021
University of Zurich
2018-2021
Hadassah Medical Center
2020
University Hospital of Bern
2014-2018
University of Bern
2018
Society of Interventional Radiology
2018
Background Recent studies have reported the additive value of combined gallium 68 (68Ga)-labeled Glu-urea-Lys (Ahx)-HBED-CC ligand targeting prostate-specific membrane antigen (PSMA) (hereafter called 68Ga-PSMA-11) PET/MRI for detection and localization primary prostate cancer compared with multiparametric MRI. Purpose To compare diagnostic accuracy interrater agreement MRI 68Ga-PSMA-11 extracapsular extension (ECE) seminal vesicle infiltration (SVI) in patients cancer. Materials Methods...
Abstract Patients with pancreatic cancer commonly develop weight loss and muscle wasting. Whether adipose tissue skeletal losses begin before diagnosis the potential utility of such for earlier detection are not well understood. We quantify areas from computed tomography (CT) imaging obtained 2 months to 5 years in 714 cases 1748 matched controls. Adipose is identified up 6 months, wasting 18 clinical present control population. Tissue similar magnitude diagnosed localized compared...
Brown adipose tissue (BAT) is a specialized form of tissue, able to increase energy expenditure by heat generation in response various stimuli. Recently, its pathological activation has been implicated the pathogenesis cancer cachexia. To establish causal relationship, we retrospectively investigated longitudinal changes BAT and large FDG-PET/CT cohort.We analyzed 13 461 examinations n = 8 409 patients at our institution from winter months 2007-2015. We graded strength based on anatomical...
Staging of liver fibrosis traditionally relied on histology; however, transient elastography (TE) and more recently two-dimensional shear wave (2D-SWE) evolved to noninvasive alternatives. Hence, we evaluated the diagnostic accuracy 2D-SWE assessed by Canon Aplio i800 ultrasound system using biopsy as reference compared performance TE.In total, 108 adult patients with chronic disease undergoing biopsy, TE were enrolled prospectively at University Hospital Zurich. Diagnostic accuracies area...
The purpose of this study was to evaluate the diagnostic performance magnetization transfer (MT) imaging and multigradient echo magnetic resonance (MRI) quantify pancreatic fibrosis lipomatosis in patients before pancreatoduodenectomy for postoperative risk stratification with histopathology as reference standard.Twenty-four (age, 68 ± 8 years, 16 males) prospectively underwent quantitative MT using a 2-dimensional gradient sequence without prepulse on 3 T MRI 1 day due adenocarcinoma head...
We report a case of 33-year-old woman with emergency admission due to dyspnoea and fever. History included squamous cell carcinoma the cervix in complete remission. Contrast-enhanced computed tomography (CT) scanning chest, which was indicated rule out pneumonia, revealed an infiltrative cardiac mass. Further assessment tumour by echocardiography magnetic resonance imaging (MRI) showed transmural infiltration apical interventricular septum mass extending into left right ventricle cavities....
To investigate the performance of MR-defecography (MRD) in lateral body position as an alternative to supine position.22 consecutive patients (16 females; mean age 51 ± 19.4) with obstructed defecation and 20 healthy volunteers (11 33.4 11.5) underwent MRD a closed-configuration 3T-MRI position. included T2 weighted images at rest during after filling rectum 250 ml water-based gel. Measurements were performed reference pubococcygeal line grade evacuation was assessed. Image quality (IQ)...
Objective The aim of this retrospective study was to evaluate the diagnostic value and measure interreader agreement pancreaticolienal gap (PLG) in assessment imaging features pancreatic carcinoma (PC) on contrast-enhanced multi-detector computed tomography (CE-MDCT). Materials Methods CE-MDCT studies portal venous phase were retrospectively reviewed for 66 patients with PC. age- gender-matched control group comprised 103 healthy individuals. Three radiologists different levels experience...
Patients with interatrial shunts (patient foramen ovale/atrial septal defect) are potentially at increased risk for paradoxical air embolism following computed tomography (CT) scans intravenous (IV) contrast media injection. IV in-line filters aim to prevent such embolisms but not compatible power injection required diagnostic CT.The purpose of this study was determine whether the incidence heart and brain in patients an shunt is higher compared controls within 48 hours without filter.This a...