Alexander Goehler

ORCID: 0000-0002-6237-2032
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Radiation Dose and Imaging
  • Health Systems, Economic Evaluations, Quality of Life
  • Ultrasound in Clinical Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced X-ray and CT Imaging
  • HIV-related health complications and treatments
  • Heart Failure Treatment and Management
  • Cardiovascular Disease and Adiposity
  • Atrial Fibrillation Management and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Gene expression and cancer classification
  • Global Cancer Incidence and Screening
  • Coronary Interventions and Diagnostics
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Venous Thromboembolism Diagnosis and Management
  • Frailty in Older Adults
  • Lung Cancer Diagnosis and Treatment
  • Radiology practices and education
  • MRI in cancer diagnosis
  • Pancreatic and Hepatic Oncology Research
  • Blood transfusion and management
  • Brain Tumor Detection and Classification
  • Cardiomyopathy and Myosin Studies
  • Adrenal and Paraganglionic Tumors

Harvard University
2011-2021

Massachusetts Institute of Technology
2021

Brigham and Women's Hospital
2013-2021

Beth Israel Deaconess Medical Center
2020-2021

Massachusetts General Hospital
2008-2019

University of Duisburg-Essen
2011-2018

Alfried Krupp von Bohlen und Halbach Foundation
2011-2018

Lemuel Shattuck Hospital
2018

Yale University
2013-2017

University of Toronto
2015

It is unclear whether an evaluation incorporating coronary computed tomographic angiography (CCTA) more effective than standard in the emergency department patients with symptoms suggestive of acute syndromes.In this multicenter trial, we randomly assigned 40 to 74 years age syndromes but without ischemic electrocardiographic changes or initial positive troponin test early CCTA on weekdays during daylight hours between April 2010 and January 2012. The primary end point was length stay...

10.1056/nejmoa1201161 article EN New England Journal of Medicine 2012-07-25

Purpose To evaluate the effect of tomosynthesis in diagnostic mammography on Breast Imaging Reporting and Data System (BI-RADS) final assessment categories over time. Materials Methods This retrospective study was approved by institutional review board. The authors reviewed all mammograms obtained during a 12-month interval before (two-dimensional [2D] [June 2, 2010, to June 1, 2011]) for 3 consecutive years after (tomosynthesis year 1 [2012], 2 [2013], [2014]) implementation tomosynthesis....

10.1148/radiol.2016151999 article EN Radiology 2016-05-03

Participation in antiretroviral therapy (ART) programmes has been associated with greater utilization of care for hypertension and diabetes rural South Africa. The objective this study was to assess whether people living HIV on ART comorbid or also have improved chronic disease management indicators.

10.1002/jia2.25213 article EN cc-by Journal of the International AIDS Society 2019-03-01

Pulmonary nodules (PNs) are often detected incidentally during coronary computed tomographic (CT) angiography, which is increasingly being used to evaluate patients with chest pain symptoms. However, the efficiency of following up on PN unknown.We determined demographic and clinical characteristics stable symptomatic referred for CT angiography in whom PNs warranted follow-up. A validated lung cancer simulation model was populated data from these patients, economic consequences follow-up per...

10.1161/circulationaha.113.007306 article EN Circulation 2014-07-12

The purpose of this study is to compare the attenuation and homogeneity renal neoplasms with those cysts on contrast-enhanced CT.A total 129 24 simple were evaluated. Two readers determined whether each mass was qualitatively heterogeneous or homogeneous. Mean, minimum, maximum values measured. Statistical analysis performed.A 116 cell carcinomas (RCCs) (99 clear cell, four papillary, oncocytic, seven chromophobe, two unclassified RCCs), 13 homogeneous RCCs (10 one chromophobe RCC), (all...

10.2214/ajr.16.17119 article EN American Journal of Roentgenology 2017-03-22

Background— Coronary computed tomographic angiography (cCTA) allows rapid, noninvasive exclusion of obstructive coronary artery disease (CAD). However, concern exists whether implementation cCTA in the assessment patients presenting to emergency department with acute chest pain will lead increased downstream testing and costs compared alternative strategies. Our aim was compare observed actual usual care (UC) projected a strategy including early evaluation Rule Out Myocardial Infarction...

10.1161/circoutcomes.113.000244 article EN Circulation Cardiovascular Quality and Outcomes 2013-09-01

Obesity has been linked to severe clinical outcomes among people who are hospitalized with coronavirus disease 2019 (COVID-19). We tested the hypothesis that visceral adipose tissue (VAT) is associated in patients COVID-19, independent of body mass index (BMI).

10.1093/ofid/ofab275 article EN cc-by-nc-nd Open Forum Infectious Diseases 2021-05-28

Prolonged Holter monitoring of patients with cerebral ischemia increases the detection rate paroxysmal atrial fibrillation (PAF); this leads to improved antithrombotic regimens aimed at preventing recurrent ischemic strokes. The aim study was compare a 7-day-Holter (7-d-Holter) alone or in combination prior selection via transthoracic echocardiography (TTE) standard 24-h-Holter using cost-utility analysis. Lifetime cost, quality-adjusted life years (QALY), and incremental cost-effectiveness...

10.1007/s00392-013-0601-2 article EN cc-by Clinical Research in Cardiology 2013-08-01

BackgroundHIV-infected patients are at increased risk of coronary artery disease (CAD). We evaluated the cost-effectiveness cardiac screening for HIV-positive men intermediate or greater CAD risk.

10.1177/2047487313483607 article EN European Journal of Preventive Cardiology 2013-03-28

Examining the Use of Comparative and Cost-Effectiveness Analyses in RadiologyAlexander Goehler1,2,3,4 G. Scott Gazelle2,3,5Audio Available | Share

10.2214/ajr.14.12887 article EN American Journal of Roentgenology 2014-10-23

A Simulation Model of Clinical and Economic Outcomes Cardiac CT Triage Patients With Acute Chest Pain in the Emergency DepartmentAlexander Goehler1 2 3, Daniel A. Ollendorf4, Marie Jaeger1, Joseph Ladapo1, Till Neumann5, G. Scott Gazelle1 6 Steven D. Pearson4Audio Available | Share

10.2214/ajr.10.4962 article EN American Journal of Roentgenology 2011-03-22

Breast cancer is the most common malignancy among women in developed countries. We a model (the Oncotyrol breast outcomes model) to evaluate cost-effectiveness of 21-gene assay when used combination with Adjuvant! Online support personalized decisions about use adjuvant chemotherapy. The goal this study was perform cross-model validation.The evaluates by simulating hypothetical cohort 50-year-old over lifetime horizon using discrete event simulation. Primary were life-years, quality-adjusted...

10.1177/0272989x15604158 article EN Medical Decision Making 2015-10-16
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