Sheng Li

ORCID: 0000-0002-0938-603X
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About
Contact & Profiles
Research Areas
  • Atmospheric chemistry and aerosols
  • Air Quality and Health Impacts
  • Vehicle emissions and performance
  • Thermochemical Biomass Conversion Processes
  • Subcritical and Supercritical Water Processes
  • Coal Combustion and Slurry Processing
  • Toxic Organic Pollutants Impact
  • Black Holes and Theoretical Physics
  • Galaxies: Formation, Evolution, Phenomena
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Air Quality Monitoring and Forecasting
  • Cosmology and Gravitation Theories
  • Neonatal Respiratory Health Research
  • Ubiquitin and proteasome pathways
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Mobile and Web Applications
  • Heat transfer and supercritical fluids
  • Heart Rate Variability and Autonomic Control
  • Odor and Emission Control Technologies
  • Acute Ischemic Stroke Management
  • Bone Metabolism and Diseases
  • Hippo pathway signaling and YAP/TAZ
  • Immune cells in cancer
  • Vascular Malformations Diagnosis and Treatment
  • Cerebral Venous Sinus Thrombosis

Chinese Academy of Sciences
2009-2023

Center for Excellence in Molecular Cell Science
2019-2023

University of Chinese Academy of Sciences
2009-2022

Guangzhou Institute of Geochemistry
2017-2022

Dalian Medical University
2022

First Affiliated Hospital Zhejiang University
2020

People's Hospital of Xinjiang Uygur Autonomous Region
2019

Institute of Engineering Thermophysics
2017-2018

University of Alabama at Birmingham
2015

Chinese People's Liberation Army
2009

Nitrous acid (HONO) is one of the most important photochemical precursors hydroxyl radical in sunlit urban atmosphere. The sources HONO, however, are still poorly characterized, yet there a disagreement between field observations and model results. Here, we show that light-induced NO2 heterogeneous chemistry on authentic grime can make an contribution to total HONO levels obtained results indicate effective uptake coefficients presence ultraviolet light [2.6 × 1015 photons cm–2 s–1 (300 nm <...

10.1021/acs.estlett.9b00308 article EN Environmental Science & Technology Letters 2019-06-17

Abstract Necroptosis, a form of programmed cell death, is characterized by the loss membrane integrity and release intracellular contents, execution which depends on membrane-disrupting activity Mixed Lineage Kinase Domain-Like protein (MLKL) upon its phosphorylation. Here we found myofibers committed MLKL-dependent necroptosis after muscle injury. Either pharmacological inhibition upstream kinase Receptor Interacting Protein Kinases 1 (RIPK1) or genetic ablation MLKL expression in led to...

10.1038/s41422-020-00393-6 article EN cc-by Cell Research 2020-08-24

Laboratory studies have demonstrated that uptake of SO2 on oleic acid (OLA) could directly produce organosulfates (OS); yet, it is unknown whether this pathway significant in secondary organosulfur production ambient air. Here, we collected filter-based samples fine particles (PM2.5) the Pearl River Delta region southern China and determined compounds with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS). The results are agreement occurrence organosulfurs formed from...

10.1021/acs.estlett.9b00218 article EN Environmental Science & Technology Letters 2019-05-06

Abstract. Hygroscopicity largely affects environmental and climatic impacts of pollen grains, one important type primary biological aerosol particles in the troposphere. However, our knowledge hygroscopicity is rather limited, effect temperature particular has rarely been explored before. In this work three different techniques, including a vapor sorption analyzer, diffusion reflectance infrared Fourier transform spectroscopy (DRIFTS) transmission (transmission FTIR) were employed to...

10.5194/acp-19-2247-2019 article EN cc-by Atmospheric chemistry and physics 2019-02-21

The photolysis of nitrous acid (HONO) is the main initiation source hydroxyl radical (OH) which in turn oxidant controlling oxidation capacity indoor atmosphere.

10.1039/c9em00194h article EN Environmental Science Processes & Impacts 2019-01-01

Abstract. Intermediate-volatility organic compounds (IVOCs) emitted from vehicles are important precursors to secondary aerosols (SOAs) in urban areas, yet vehicular emission of IVOCs, particularly on-road fleets, is poorly understood. Here we initiated a field campaign collect IVOCs with sorption tubes at both the inlet and outlet busy tunnel (&gt;30 000 per day) south China for characterizing emissions vehicles. The average factor (EFIVOCs) was measured be 16.77±0.89 mg km−1 (average ±95 %...

10.5194/acp-21-10005-2021 article EN cc-by Atmospheric chemistry and physics 2021-07-06

Abstract Organic nitrogen aerosols are complex mixtures and important compositions in ambient fine particulate matters (PM 2.5 ), yet their sources spatiotemporal patterns not well understood particularly regions influenced by intensive human activities. In this study, filter‐based PM samples at four stations (one urban, two rural, plus one urban roadside) from combustion (vehicle exhaust, ship emission, biomass burning) were collected the coastal megacity Guangzhou, south China, for...

10.1002/2017jd027327 article EN Journal of Geophysical Research Atmospheres 2017-11-21

ABSTRACT Periapical disease, an inflammatory disease mainly caused by dental caries, is one of the most prevalent infectious diseases humans, affecting both children and adults. The infection travels through root, leading to inflammation, bone destruction, severe pain for patient. Therefore, development a new class anti-periapical therapies necessary critical treatment prevention. A small molecule, odanacatib (ODN), which cathepsin K (Ctsk) inhibitor, was investigated determine its ability...

10.1128/iai.01713-14 article EN Infection and Immunity 2015-01-13

10.1016/j.physletb.2008.12.056 article EN Physics Letters B 2009-01-02

In this paper, a novel high-efficiency coal gasification technology is proposed in which regenerative unit applied to recover syngas sensible heat generate steam; then, the high-temperature steam used gasify coke from pyrolyzer. Through such thermochemical unit, with lower energy level upgraded into chemical higher level; therefore, high cold gas efficiency (CGE) expected system. aspenplus software selected simulate system, and key parameters are validated by experimentation. Then energy,...

10.1115/1.4039978 article EN Journal of Energy Resources Technology 2018-05-07

Abstract Globally water‐soluble organic nitrogen (WSON) accounts for about one third of total in atmospheric deposition, yet the key factors influencing WSON deposition remain uncertain. In present study, precipitation and aerosol samples were collected during 2016–2018 at a forest site Pearl River Delta, south China. Rainwater concentrations found to elevate significantly fall, wet fall could account 50% its annual deposition. The rainwater K + levoglucosan, which are tracers biomass...

10.1029/2020jd032699 article EN cc-by Journal of Geophysical Research Atmospheres 2020-08-31

Spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and cord injury (SCI). These are currently incurable, while human pluripotent stem cells (hPSCs)-derived promising but suffered from inappropriate regional identity functional immaturity for the study treatment posterior related injuries. In this study, we have established neural progenitor (hSCNPCs) via hPSCs differentiated neuromesodermal...

10.1186/s13619-023-00159-6 article EN cc-by Cell Regeneration 2023-03-23

In a given path with multiple branches, in principle, it can be expected that there are some fork points, where one branch is bifurcated into different or various branches converge several branches. this paper, showed if web formed by such field space, which each responsible for period of slow roll inflation, multiverse separated domain wall network will come being, might corresponds to our observable universe. We discuss scenario and show possible observations observer at late time.

10.1103/physrevd.80.123535 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D, Particles, fields, gravitation, and cosmology 2009-12-29

Gasification is the core unit of coal-based production systems and also site where one largest exergy destruction occurs. This paper reveals mechanism carbon gasification through a combined analysis kinetic method energy utilization diagram (EUD). Instead lumped using traditional “black-box” other models, role each reaction in revealed. The results show that caused by chemical reactions accounts for 86.3% entire process. Furthermore, approximately 90.3% exothermal partial oxidation (reaction...

10.1115/1.4036957 article EN Journal of Energy Resources Technology 2017-06-07
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