A5042866367- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- HIV-related health complications and treatments
- Vitamin D Research Studies
- Bone health and osteoporosis research
- Liver Disease and Transplantation
- Parathyroid Disorders and Treatments
- HIV/AIDS drug development and treatment
- Systemic Lupus Erythematosus Research
- SARS-CoV-2 and COVID-19 Research
- Growth Hormone and Insulin-like Growth Factors
- Digestive system and related health
- Nutrition, Genetics, and Disease
- Urological Disorders and Treatments
- Viral-associated cancers and disorders
- Coffee research and impacts
- Nutrition and Health in Aging
- Tea Polyphenols and Effects
- Radiopharmaceutical Chemistry and Applications
- Congenital heart defects research
- Obesity, Physical Activity, Diet
- Vaccine Coverage and Hesitancy
- Liver Diseases and Immunity
- Bipolar Disorder and Treatment
Bordeaux Population Health
2016-2022
Université de Bordeaux
2017-2022
Clinical Investigation Center Plurithematic Tours
2018-2022
Inserm
2009-2021
Bicêtre Hospital
2014-2021
Assistance Publique – Hôpitaux de Paris
2014-2021
Inserm Transfert
2020
Universidade de Brasília
2018
Université Paris-Sud
2017
Hôpital Saint-Vincent-de-Paul
2009-2010
Background. Human immunodeficiency virus (HIV)/hepatitis C (HCV)–coinfected patients with cirrhosis have long been considered to be difficult treat, and real-life efficacy tolerance data all-oral direct-acting antiviral (DAA) combinations in these are scarce. Methods. Cirrhotic HIV/HCV-coinfected enrolled the French National Agency for Research on AIDS Viral Hepatitis (ANRS) CO13 HEPAVIH cohort initiating an DAA regimen were consecutively included. A negative HCV RNA result at 12 weeks of...
The prevalence of lower limb deformities physiologically decreases after 5 years age. It remains high in some tropical and subtropical regions where it has been associated with severe vitamin D deficiency, low calcium/milk intakes, malnutrition, and/or fluoride overexposure. Very little data is available apparently healthy Caucasian children adolescents.We evaluated the genu varum/valgum other clinical symptoms, assessed status markers calcium metabolism 226 European full-time boarders (7-16...
Coffee intake has been shown to modulate both the effect of ethanol on serum GGT activities in some alcohol consumers and risk alcoholic cirrhosis patients with chronic diseases. This study aimed analyze impact coffee consumption advanced liver fibrosis (ALF) HIV-HCV co-infected patients.ANRS CO13-HEPAVIH is a French, nationwide, multicenter cohort HIV-HCV-co-infected patients. Sociodemographic, behavioral, clinical data including were prospectively collected using annual self-administered...
Few data exist on changes to substance use patterns before and after hepatitis C virus (HCV) treatment. We used longitudinal of HIV-HCV co-infected individuals examine whether receiving pegylated interferon (Peg-IFN)-based therapy irrespective HCV clearance could modify tobacco, cannabis alcohol use.A prospective cohort was enrolled from 2006. Participants' clinical were retrieved medical records socio-demographic behavioural characteristics collected by yearly self-administered...
Background and Aims Human immunodeficiency virus (HIV)–hepatitis C (HCV)–coinfected patients are at high risk of metabolic complications liver‐related events, which both associated with hepatic steatosis its progressive form, nonalcoholic steatohepatitis, a known factor for mortality. The fatty liver index (FLI), noninvasive biomarker, has recently drawn attention clinical prognostic value, although capacity to predict mortality in HIV–HCV‐coinfected never been investigated. Using Cox...
Except after neck surgery, hypoparathyroidism is a rare disease caused by defects in genes involved parathyroid gland development (TBX1/22q11.2 del, GCMB, GATA3, TBCE) or function [calcium sensing receptor (CASR), GNA11, PTH], the autoimmune polyglandular syndrome type 1 (AIRE). Approximately 90% of sporadic cases and 30% familial isolated remain unexplained. Recurrent missense mutations AP2S1, calcium-sensing regulator, have been recently identified hyperparathyroidism.The aim study was to...
An increased risk of cardiovascular disease (CVD) was reported in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C (HCV), without identifying factors associated atherosclerotic CVD (ASCVD) events.HIV-HCV were enrolled the Agence Nationale de Recherches sur le Sida et les hépatites virales (ANRS) CO13 HEPAVIH nationwide cohort. Primary outcome total ASCVD events. Secondary outcomes coronary and/or cerebral events, peripheral artery (PAD) Incidences estimated using...
Hypospadias (H) is a common birth defect affecting the male urinary tract. It has been suggested that exposure to endocrine disrupting chemicals might increase risk of H by altering urethral development. However, whether increased in places heavily exposed agricultural pesticides, such as vineyards, remains debated and difficult ascertain. The objective work test possible association with residential proximity vineyards. Residential address at 8,766 cases born 1980–2011 was taken from 17...
Background The association between liver stiffness measurements (LSM) and mortality has not been fully described. In particular the effect of LSM on all-cause taking sustained virological response (SVR) into account needs further study. Methods HIV/HCV participants in French nation-wide, prospective, multicenter ANRS CO13 HEPAVIH cohort, with ≥1 by FibroScan (FS) a detectable HCV RNA when first valid FS was performed were included. Cox proportional hazards models delayed entry to determine...
To analyze the impact of fatigue on individuals' global, cognitive, physical, and psychosocial functioning in long term after hepatitis C virus (HCV) treatment its relationship with HCV clearance among patients coinfected HIV exposed to peg-interferon/ribavirin-containing regimens.The study sample included 107 treated for during follow-up French ANRS CO13-HEPAVIH cohort. Analyses used scores from Fatigue Impact Scale (FIS), assessed before initiation at last available measure end (2 years...
The International Collaboration on Hepatitis C Elimination in HIV Cohorts (InCHEHC) is a multinational consortium of longitudinal cohorts people with who are at risk hepatitis virus (HCV) infection or infected HCV.InCHEHC has been specifically designed to assess progress towards HCV elimination as public health threat among HIV.• first data merge includes 104 740 participants from 11 Australia (n ¼ 22 033), Canada 2070), France 18 387), Netherlands 24 785), Spain 16 725) and Switzerland 20...
The aim of this study is to document the relationship between anger dimensions (state, trait, expression, and control) quality life (QoL) in patients co-infected with HIV hepatitis C virus (HCV).This a cross-sectional nested ANRS CO13-HEPAVIH French national cohort. Anger QoL were assessed using self-administered questionnaires 536 HIV-HCV-co-infected patients. Correlations scores (STAXI-2 scale) (WHOQOL-HIV BREF Spearman's coefficients. Multiple linear regression models then used test...
Compared to the general population, HIV-infected patients are at higher risk of developing non-AIDS-defining cancers. Chronic HCV infection has also been associated with a than that population cancers other hepatocarcinoma. Evaluation impact HCV-related factors on and non HCV-liver (NANL) related among HIV/HCV co-infected scarce. The aim this study was identify clinical characteristics NANL in large cohort HIV/HCV-coinfected followed from 2005 2017. Cox proportional hazards models delayed...
Background Direct-acting antivirals (DAA) have dramatically increased HCV cure rates with minimal toxicity in HIV-HCV co-infected patients. This study aimed to compare the socio-behavioral characteristics of patients initiating pegylated-interferon (PEG-IFN)-based treatment those DAA-based treatment. Methods ANRS CO13 HEPAVIH is a national multicenter prospective cohort started 2005, which enrolled 1,859 followed up French hospital outpatient units. Both clinical/biological and data were...