Marta Rava
A5063445881- Bladder and Urothelial Cancer Treatments
- Asthma and respiratory diseases
- HIV/AIDS Research and Interventions
- Air Quality and Health Impacts
- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Indoor Air Quality and Microbial Exposure
- Neonatal Respiratory Health Research
- Urinary and Genital Oncology Studies
- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Noise Effects and Management
- Respiratory and Cough-Related Research
- Ferroptosis and cancer prognosis
- Pancreatic and Hepatic Oncology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Cancer, Lipids, and Metabolism
- HIV, Drug Use, Sexual Risk
- Occupational exposure and asthma
- Air Quality Monitoring and Forecasting
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Gut microbiota and health
Instituto de Salud Carlos III
2020-2025
National Center for Epidemiology
2023-2025
Centre for Biomedical Network Research on Rare Diseases
2023-2025
Centro Nacional de Epidemiología
2020-2024
Red de Investigación en Sida
2021-2024
Centro de Investigación Biomédica en Red
2022-2024
Instituto Ramón y Cajal de Investigación Sanitaria
2023
Research Network (United States)
2021
Centro de Investigación del Cáncer
2015-2020
Spanish National Cancer Research Centre
2014-2020
The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern. present study aimed to assess time trends in current asthma, asthma-like symptoms and allergic rhinitis Italian adults from 1990 2010. same screening questionnaire was administered by mail or phone random samples general population (age 20–44 yrs) Italy, frame three multicentre studies: European Community Respiratory Health Survey (ECRHS) (1991–1993; n=6,031); Study on...
Abstract Purpose: Urothelial bladder cancer presents high recurrence rates, mandating continuous monitoring via invasive cystoscopy. The development of noninvasive tests for disease diagnosis and surveillance remains an unmet clinical need. In this study, validation two urine-based biomarker panels detecting primary recurrent urothelial was conducted. Experimental Design: Two studies (total n = 1,357) were performed (n 721) relapsed 636). Cystoscopy applied cancer, while patients negative...
To cite this article: de Marco R, Pesce G, Girardi P, Marchetti Rava M, Ricci Marcon A. Foetal exposure to maternal stressful events increases the risk of having asthma and atopic diseases in childhood. Pediatr Allergy Immunol 2012: 23 : 724–729. Abstract Background: The natural history begins utero . Studies investigating influence foetal life during pregnancy (SLEP) on are lacking. Aim: test whether children mothers who had experienced SLEP at an increased for asthma, eczema allergic...
Objectives To characterise the association between type 2 diabetes mellitus (T2DM) subtypes (new-onset T2DM (NODM) or long-standing (LSDM)) and pancreatic cancer (PC) risk, to explore direction of causation through Mendelian randomisation (MR) analysis assess mediation role body mass index (BMI). Design Information about related factors was collected from 2018 PC cases 1540 controls PanGenEU (European Study into Digestive Illnesses Genetics) study. A subset had glycated haemoglobin,...
Abstract Objectives To assess the effectiveness and tolerability of dolutegravir (DTG)/lamivudine (3TC) among treatment-naive virologically suppressed treatment-experienced individuals in multicentre cohort Spanish HIV/AIDS Research Network (CoRIS) during years 2018–2021. Methods We used multivariable regression models to compare viral suppression (VS) [HIV RNA load (VL) <50 copies/mL] change CD4 cell counts at 24 48 (±12) weeks after initiation with dolutegravir/lamivudine or other...
Platinum-based neoadjuvant chemotherapy (NAC) increases the survival of patients with organ-confined urothelial bladder cancer (UBC). In retrospective studies, basal/squamous (BASQ)-like tumors present more advanced disease and have worse prognosis. Transcriptomics-defined tumor subtypes are associated response to NAC.
With the purpose of reducing well-known negative impact late presentation (LP) on people living with HIV (PLWH), guidelines early diagnosis were published in 2014 Spain, but since then no data LP prevalence have been published. To estimate and risk factors to evaluate their development clinical outcomes Cohort Spanish HIV/AIDS Research Network (CoRIS) during 2004-2018.CoRIS is an open prospective multicenter cohort PLWH, adults, naive ART at entry. was defined as CD4 count ≤350 cells/μL or...
BackgroundWhile a low CD4/CD8 ratio during HIV treatment correlates with immunosenescence, its value in identifying patients at an increased risk for clinical events remains unclear.MethodsWe analyzed data from the CoRIS cohort to determine whether CD4 count, CD8 and year two of antiretroviral therapy (ART) could predict serious non-AIDS (SNAEs) next five years. These included major adverse cardiovascular events, non-AIDS-defining malignancies, non-accidental deaths. We used pooled logistic...
Objective: We assessed the association between early HIV medical care interruption (MCI) and development of AIDS-defining events (ADEs), serious non-AIDS (SNAEs), death among people with (PWH) from CoRIS cohort. Design: included antiretroviral-naive individuals aged at least 18 years enrollment, recruited 1 January 2004 30 May 2021, followed-up until November 2023. Methods: Early MCI was defined as a time interval over 15 months two consecutive visits, where first these visits occurred...
<h3>Background</h3> Cured meat intake—a recent carcinogenic factor—may increase the risk of COPD, but its association with asthma remains unknown. Though body mass index (BMI) is a likely factor for asthma, role in diet–asthma as mediator has never been studied. We investigated between cured intake and worsening symptoms adults, BMI potential mediator. <h3>Methods</h3> Using data from French prospective EGEA study (baseline: 2003–2007; follow-up: 2011–2013), we applied mediation analysis...
8-Hydroxydeoxyguanosine (8-OHdG) is a commonly used marker of DNA oxidative stress in epidemiological studies. The aim this study was to establish whether the urinary concentration 8-OHdG varies during first part day, when clinical tests are usually performed, and it can therefore be measured without bias spot urine samples.Spot samples were collected using convenience sample. A linear mixed-effects model for repeated measurements analyze levels.A significant increasing trend time found...
Family history (FH) of pancreatic cancer (PC) has been associated with an increased risk PC, but little is known regarding the role inherited/environmental factors or that FH other comorbidities in PC risk. We aimed to address these issues using multiple methodological approaches.
Objective: To estimate life expectancy of people with HIV (PWH) and describe causes death. Design: Antiretroviral therapy (ART)-naive adults from the CoRIS cohort starting ART in 2004–2019. Methods: We calculated at age 40 for men women according to their initiation period, stratified by transmission category, CD4 + cell count AIDS diagnosis. estimated 10-year bands using tables constructed mortality rates, through Poisson models. Results: Life increased 65.8 [95% confidence interval (CI)...
Although interest in biomarkers the nitrate–nitrite–NO pathway has recently increased, associations between nitrite (NO 2 − ) and nitrate 3 ), asthma, allergic sensitisation rhinitis remain unclear. The study aimed to evaluate NO /NO exhaled fraction of nitric oxide ( F eNO levels with rhinitis. Plasma breath condensate (EBC) were measured 523 adults French Epidemiological on Genetics Environment Asthma. Allergic was defined by a positive skin prick test for at least one aeroallergen....
Objectives: The aim of this study was to examine the impact late presentation (CD4 + cell count <350 cells/μl or an AIDS-defining event) on effectiveness and safety initial antiretroviral therapy (ART) evaluate whether treatment response depends first-line ART regimen in presenters. Design: ART-naive adults from Cohort Spanish HIV/AIDS Research Network (CoRIS) starting triple between 2010 2018. Methods: We used multivariable models assess differences viral suppression (viral load <50...
Over the past decade, antiretroviral therapy (ART) regimens that include integrase strand inhibitors (INSTIs) have become most commonly used for people with HIV starting ART. Although trials and observational studies compared virological failure on INSTI-based other regimens, few data are available mortality in treated INSTIs routine care. Therefore, we all-cause between different non-INSTI-based adults ART from 2013 to 2018.