A5004607729- Asthma and respiratory diseases
- Schizophrenia research and treatment
- Respiratory and Cough-Related Research
- Traffic and Road Safety
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Psychiatry, Mental Health, Neuroscience
- Psychiatric care and mental health services
- Injury Epidemiology and Prevention
- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Educational and Social Studies
- Occupational Health and Safety Research
- Mental Health Treatment and Access
- Infectious Diseases and Tuberculosis
- Neonatal Respiratory Health Research
- Mental Health and Psychiatry
- Health Systems, Economic Evaluations, Quality of Life
- Safety Warnings and Signage
- Diet and metabolism studies
- Agriculture and Farm Safety
- Hepatitis B Virus Studies
- Tuberculosis Research and Epidemiology
- HIV Research and Treatment
- Autopsy Techniques and Outcomes
- Automotive and Human Injury Biomechanics
University of Milan
1995-2025
University of Pavia
2004-2016
Department of Medical Sciences
2004
Pavia nel Cuore
2003
Hospital Universitário Clementino Fraga Filho
2001
Universidade Federal do Rio de Janeiro
2001
Ospedale L. Bonomo
2000
King's College London
1999
Organizzazione Sociopsichiatrica Cantonale
1997
The Factor V Leiden and prothrombin-gene mutations are independent risk factors for venous thrombosis; it is debated whether a mutation in the gene encoding methylenetetrahydrofolate reductase, an enzyme involved homocysteine metabolism, also increases of thrombosis. Whether any these associated with increased late fetal death not known.
The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern. present study aimed to assess time trends in current asthma, asthma-like symptoms and allergic rhinitis Italian adults from 1990 2010. same screening questionnaire was administered by mail or phone random samples general population (age 20–44 yrs) Italy, frame three multicentre studies: European Community Respiratory Health Survey (ECRHS) (1991–1993; n=6,031); Study on...
<i>Background/Aims:</i> Up to now, few cost-of-illness (COI) studies have estimated the cost of adult asthma at an individual level on general population samples. We sought evaluate current from societal perspective in young Italian adults and determinants variation. <i>Methods:</i> In 2000, a COI study was carried out frame Study Asthma Young Adults 527 asthmatics (20–44 years) screened 15,591 subjects seven centres. Detailed information about direct medical...
Background: Few data are available on the asthma burden in general population. We evaluated level and factors associated with Europe. Methods: In 1999–2002, 1152 adult asthmatics were identified European Community Respiratory Health Survey (ECRHS)‐II socio‐economic (reduced activity days hospital services utilization past 12 months) was assessed. Results: The a light (only few reduced days) 13.2% (95% CI: 11.4–15.3%), whereas those heavy (many and/or utilization) 14.0% 12.1–16.1%). strongly...
Intramammary dry-off treatment is widely considered an effective method for preventing and curing intramammary infection (IMI) in lactating cows; however, it not commonly used small ruminants like goats. Therefore, this study was designed to evaluate the effect of approved cefazolin-based on milk microbiota Alpine dairy goats during dry early lactation periods. Sixty were randomly selected based bacteriological results allocated into control group (CG) or (TG). Cefazolin 250 mg (Cefovet A,...
In the early 1990s a multicentre survey on asthma was performed young adult population (European Community Respiratory Health Survey - ECRHS). This study is to be repeated in order estimate changes prevalence of asthma-like symptoms during last decade and assess social economic costs disease their variations among countries. The self-administered questionnaire devised for this purpose two-page questionnaire. first page contains same items as those used with four additional questions related...
Background: Variations in the prevalence of respiratory symptoms according to geo‐climatic factors could provide important clues knowledge aetiology asthma. Methods: Geo‐climatic variations current asthma, allergic rhinitis and chronic cough, phlegm were assessed on a random sample 18 873 subjects (response rate = 72.7%) from different climatic regions Italy. An ecological analysis, supported by robust statistical methods, was employed investigate potential trends. Results: The all...
The role of genetic and environmental factors, as well their interaction, in the natural history asthma, allergic rhinitis chronic obstructive pulmonary disease (COPD) is largely unknown. This mainly due to lack large-scale analytical epidemiological/genetic studies aimed at investigating these 3 respiratory conditions simultaneously. GEIRD project a collaborative initiative designed collect information on biomarkers inflammation oxidative stress, individual ecological exposures, diet,...
Background: Few data are available on the management of asthma in general population. The aim this study was to evaluate level control Italian patients, a decade after publication international guidelines. Materials and methods: Within framework multicentre, population‐based people aged 20–44 years, 18 873 subjects replied postal screening questionnaire (response rate = 72.7%) presence symptoms exacerbations, their impact daily life. All reporting having ever had doctor diagnosis either...
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines underline that the presence of chronic cough and sputum production before airflow obstruction offers a unique opportunity to identify subjects at risk obstructive pulmonary disease an early intervention. Current epidemiological data on these are scant. Between 1998–2000, authors evaluated prevalence characteristics symptoms by multicentre cross-sectional survey Italian people aged between 20–44 yrs from general...
<i>Background:</i> The guidelines for asthma recommend that the use of anti-inflammatory therapy should be adapted to severity disease. However, few data are available assess adequacy drugs and its influence on control in ‘real life’. <i>Methods:</i> current anti-asthmatic medication according Global Initiative Asthma (GINA) was assessed a random sample 400 asthmatics identified frame Italian Study Young Adults. using GINA criteria; accordingly, patient classified as...
Abstract Background Few longitudinal data exist on the incidence of asthma in young adults and overall mortality risk due to asthma. A 7-year follow-up prospective study was performed assess from all causes a cohort adults. Methods The life status 6031 subjects, aged 20–44 years, who replied respiratory screening questionnaire between 1991 1992, ascertained 1999. new investigating history subsequently sent 5236 subjects were still alive residents areas study. 3880 (74%) second questionnaire....
Mental health and addiction services have traditionally evolved separately in many European countries, with policy reflecting this. Differences severity profiles between users of the community comorbidities mental illness substance misuse those only were studied using a matched case-control study design, regard to main (opiates or cocaine) patients dependent on. Patterns abuse diagnostic features evaluated according Addiction Severity Index (ASI) DSM-IV. Mentally ill abusers are...
We assessed the infectiousness of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative individuals with pulmonary tuberculosis (TB) in a prospective cohort study. enrolled, evaluated, followed 104 close contacts HIV-seropositive TB patients 256 using standardized questionnaire, symptom review, chest radiograph, HIV serology, tuberculin skin testing (TST). Contacts were for ⩾ 12 mo. infection at enrollment was 27% (28/104) among 35% (90/256) (odds ratio [OR] = 0.68, 95%...
Italian data on the prevalence of allergic rhinitis are sparse and with wide variations, maybe because different diagnostic criteria methods investigation. This study analyzes information collected in northern Italy through standardized within European Community Respiratory Health Survey.A screening questionnaire was sent by mail to a random sample general population aged 20-44 years, nonresponders were contacted again phone, achieving final response rate 86% (6031/7000). Among responders,...
Twenty-seven HIV-1-infected patients, 16 at early stage of disease and without concomitant antiretroviral therapy 11 more advanced receiving therapy, have been followed since their enrollment, November 1992 July 1993, respectively, in phase I/II studies to evaluate safety immunogenicity an anti-interferon-alpha (IFN-alpha) vaccine, aimed modulating the impaired cytokine network AIDS patients by counteracting IFN-alpha overproduction. We compared clinical, virological, immunological markers...
The European Community Respiratory Health Survey is an international survey of the general population which aims to establish whether there are significant variations in prevalence asthma among countries. present paper reports and asthma‐like symptoms a sample subjects living three areas northern Italy: Turin, Pavia, Verona. Samples residents 20–44 years old (3000 Turin Verona 1000 Pavia) stratified by sex (M:E= 1/1) were randomly selected from local health authority lists participating...